Search Results - "Otterson, M F"

Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition by Binion, D G, Otterson, M F, Rafiee, P

“…Angiogenesis, the growth of new blood vessels, is a critical homeostatic mechanism which regulates vascular populations in response to physiological…”
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Radiation induced small bowel “web” formation is associated with acquired microvascular dysfunction by Hatoum, O A, Binion, D G, Phillips, S A, O’Loughlin, C, Komorowski, R A, Gutterman, D D, Otterson, M F

“…Background and aims: Radiation therapy of abdominal and pelvic solid tumours results in late intestinal toxicity of a severe nature in approximately 5% of…”
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Propagation of giant migrating contractions between the small intestine, cecum and colon during radiation by Otterson, M. F., Leming, S. C., Fox, C. J., Moulder, J. E.

“…Background  Radiation increases the frequency of small intestinal and colonic giant migrating contractions (GMCs). These contractions contribute to the…”
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Gastrointestinal motor effects of erythromycin by Otterson, M F, Sarna, S K

“…We studied the small intestinal motor effects of oral and intravenous (iv) erythromycin in 10 conscious dogs. After control recordings with placebo, oral or iv…”
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Angiogenic Effects of Interleukin 8 (CXCL8) in Human Intestinal Microvascular Endothelial Cells Are Mediated by CXCR2 by Heidemann, Jan, Ogawa, Hitoshi, Dwinell, Michael B, Rafiee, Parvaneh, Maaser, Christian, Gockel, Henning R, Otterson, Mary F, Ota, David M, Lugering, Norbert, Domschke, Wolfram, Binion, David G

“…Angiogenesis plays a critical role in metastasis and tumor growth. Human tumors, including colorectal adenocarcinoma, secrete angiogenic factors, inducing…”
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Nitric oxide production is diminished in colonic circular muscle from acquired megacolon by Koch, T R, Otterson, M F, Telford, G L

“…Nitric oxide modulates human colonic smooth muscle function. To determine whether nitric oxide production is altered in colon from acquired megacolon, we…”
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Normal physiology of small intestinal motility by Otterson, M F, Sarr, M G

“…The small intestine produces a number of different contractions in various spatial and temporal patterns that promote efficient digestion, absorption, and…”
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Radiation Induces Endothelial Dysfunction in Murine Intestinal Arterioles via Enhanced Production of Reactive Oxygen Species by Hatoum, Ossama A, Otterson, Mary F, Kopelman, Doron, Miura, Hiroto, Sukhotnik, Igor, Larsen, Brandon T, Selle, Rebecca M, Moulder, John E, Gutterman, David D

“…OBJECTIVE—Endothelial dysfunction and vascular dysregulation contribute to the pathological effects of radiation on tissues. The objectives of this study were…”
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Neural control of small intestinal giant migrating contractions by Otterson, M F, Sarna, S K

“…We investigated the neural mechanisms of control of giant migrating contractions (GMCs) in five conscious dogs. After control recordings, a Thiry-Vella loop…”
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Fractionated irradiation alters enteric neuroendocrine products by OTTERSON, M. F, KOCH, T. R, ZHENG ZHANG, LEMING, S. C, MOULDER, J. E

“…Radiation profoundly alters the contractile activity of the small intestine and colon. We hypothesized that some motor changes of the gut might be secondary to…”
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Mechanisms of Endotoxin Tolerance in Human Intestinal Microvascular Endothelial Cells by Ogawa, Hitoshi, Rafiee, Parvaneh, Heidemann, Jan, Fisher, Pamela J, Johnson, Nathan A, Otterson, Mary F, Kalyanaraman, Balaraman, Pritchard, Kirkwood A., Jr, Binion, David G

“…Lipopolysaccharide (endotoxin) tolerance is well described in monocytes and macrophages, but is less well characterized in endothelial cells. Because…”
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Altered motility causes the early gastrointestinal toxicity of irradiation by Erickson, B A, Otterson, M F, Moulder, J E, Sarna, S K

“…Total abdominal radiation produces symptoms of nausea, vomiting abdominal cramping and diarrhea. Each of these symptoms is associated with disordered…”
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Small intestinal amyogenesia and dysmyogenesia induced by morphine and loperamide by Sarna, S K, Otterson, M F

“…We studied the effects of morphine and loperamide on small bowel myoelectric and contractile activity in 12 conscious dogs. After initially producing premature…”
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Gene expression and transcript size of the prepro-peptide VIP/PHM-27 in normal human tissue by Schulte-Bockholt, A, Meier, D A, Hopp, K, Stadelmann, A, Otterson, M F, Telford, G L, Koch, T R

“…The transcript size of VIP/PHM-27 mRNA (vasoactive intestinal peptide/peptide histidine methionine) and the relative distribution of VIP/PHM-27 gene expression…”
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Decreased vasoactive intestinal peptide levels and glutathione depletion in acquired megacolon by KOCH, T. R, SCHULTE-BOCKHOLT, A, OTTERSON, M. F, TELFORD, G. L, STRYKER, S. J, BALLARD, T, OPARA, E. C

“…We reported decreased vasoactive intestinal peptide levels in acquired megacolon. The origin of altered neuropeptide levels is unknown, but recent work…”
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Effects of fractionated doses of ionizing radiation on small intestinal motor activity by Otterson, M F, Sarna, S K, Moulder, J E

“…The small intestinal motor effects of fractionated doses of ionizing radiation were studied in 6 conscious dogs. Eight strain-gauge transducers were implanted…”
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Effects of fractionated doses of ionizing radiation on colonic motor activity by Otterson, M F, Sarna, S K, Leming, S C, Moulder, J E, Fink, J G

“…The colonic motor effects of fractionated irradiation were studied in five conscious dogs. Seven colonic and two ileal strain gauge transducers were implanted…”
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Novel Mechanism of Vasodilation in Inflammatory Bowel Disease by Hatoum, Ossama A, Gauthier, Kathryn M, Binion, David G, Miura, Hiroto, Telford, Gordon, Otterson, Mary F, Campbell, William B, Gutterman, David D

“…OBJECTIVE—Endothelium-dependent dilation to acetylcholine (Ach) is reduced in mucosal arterioles from patients with inflammatory bowel disease (IBD). The…”
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Fractionated doses of ionizing radiation alter postprandial small intestinal motor activity by OTTERSON, M. F, SARNA, S. K, LEE, M. B

“…We investigated the effects of total abdominal fractionated irradiation on postprandial small intestinal motor activity in five dogs. Five strain-gauge…”
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Characterization of neuropeptides extracted from canine intestine by Koch, T R, Otterson, M F, Roddy, D R, Go, V L

“…Quantitative determination of neuropeptides in biologic tissues by radioimmunoassay requires both an efficient extraction of neuropeptides as well as…”
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