Search Results - "Ottersen, O.P"

Expression and functional characterization of transient receptor potential vanilloid-related channel 4 (TRPV4) in rat cortical astrocytes by Benfenati, V, Amiry-Moghaddam, M, Caprini, M, Mylonakou, M.N, Rapisarda, C, Ottersen, O.P, Ferroni, S

“…Abstract Cell–cell communication in astroglial syncytia is mediated by intracellular Ca2+ ([Ca2+ ]i ) responses elicited by extracellular signaling molecules…”
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Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes by Bergersen, L H, Morland, C, Ormel, L, Rinholm, J E, Larsson, M, Wold, J F H, Røe, A T, Stranna, A, Santello, M, Bouvier, D, Ottersen, O P, Volterra, A, Gundersen, V

“…Glutamate and the N-methyl-D-aspartate receptor ligand D-serine are putative gliotransmitters. Here, we show by immunogold cytochemistry of the adult…”
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Anchoring of aquaporin-4 in brain: Molecular mechanisms and implications for the physiology and pathophysiology of water transport by Amiry-Moghaddam, M., Frydenlund, D.S., Ottersen, O.P.

“…Astrocytes show an enrichment of aquaporin-4 (AQP4) in those parts of the plasma membrane that are apposed to pial or perivascular basal laminae. This…”
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Presynaptic PICK1 facilitates trafficking of AMPA-receptors between active zone and synaptic vesicle pool by Haglerød, C, Hussain, S, Nakamura, Y, Xia, J, Haug, F.M, Ottersen, O.P, Henley, J.M, Davanger, S

“…Highlights • AMPA receptors are present at the active zone and on presynaptic vesicles. • GluA2 subunit colocalizes with PICK1 on presynaptic vesicles. •…”
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Global Governance for Health: how to motivate political change? by McNeill, D, Ottersen, O.P

“…Abstract In this article, we address a central theme that was discussed at the Durham Health Summit: how can politics be brought back into global health…”
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Genome instability and DNA repair in brain, ageing and neurological disease by Bohr, V.A, Ottersen, O.P, Tønjum, T

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Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain by Rafiki, A, Boulland, J.L, Halestrap, A.P, Ottersen, O.P, Bergersen, L

“…Monocarboxylate transporters (MCTs) play an important role in the metabolism of all cells. They mediate the transport of lactate and pyruvate but also some…”
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Aquaporins: multifarious roles in brain by Amiry-Moghaddam, M, Hoddevik, E.H, Ottersen, O.P

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Beta-amyloid causes downregulation of calcineurin in neurons through induction of oxidative stress by Celsi, F, Svedberg, M, Unger, C, Cotman, C.W, Carrì, M.T, Ottersen, O.P, Nordberg, A, Torp, R

“…Abstract Calcineurin is an abundant cytosolic protein that is implicated in the modulation of glutamate release. Here we show that the expression level of this…”
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Towards a molecular understanding of water homeostasis in the brain by Agre, P., Nielsen, S., Ottersen, O.P.

“…Editorial…”
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Ascorbate attenuates trimethyltin-induced oxidative burden and neuronal degeneration in the rat hippocampus by maintaining glutathione homeostasis by Shin, E.-J., Suh, S.K., Lim, Y.K., Jhoo, W.-K., Hjelle, O.P., Ottersen, O.P., Shin, C.Y., Ko, K.H., Kim, W.-K., Kim, D.S., Chun, W., Ali, S., Kim, H.-C.

“…The specific role of endogenous glutathione in response to neuronal degeneration induced by trimethyltin (TMT) in the hippocampus was examined in rats. A…”
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New insights in cerebellar function by Strata, P, Thach, W.T, Ottersen, O.P

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Protein interacting with C kinase 1 (PICK1) and GluR2 are associated with presynaptic plasma membrane and vesicles in hippocampal excitatory synapses by Haglerød, C, Kapic, A, Boulland, J.-L, Hussain, S, Holen, T, Skare, Ø, Laake, P, Ottersen, O.P, Haug, F.-M.S, Davanger, S

“…Abstract AMPA receptors have been identified in different populations of presynaptic terminals and found to be involved in the modulation of neurotransmitter…”
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Increased Aquaporin-4 Immunoreactivity in Rat Brain in Response to Systemic Hyponatremia by Vajda, Z., Promeneur, D., Dóczi, T., Sulyok, E., Frøkiær, J., Ottersen, O.P., Nielsen, S.

“…The present study was undertaken to assess whether the protein and mRNA expression levels of the glial water channel aquaporin-4 (AQP4) undergo downregulation…”
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Neuronal enriched endosomal protein of 21 kDa colocalizes with glutamate receptor subunit GLUR2/3 at the postsynaptic membrane by Utvik, J.K, Haglerød, C, Mylonakou, M.N.I, Holen, T, Kropf, M, Hirling, H, Skare, Ø, Laake, P, Ottersen, O.P, Haug, F.-M.S, Davanger, S

“…Abstract Functional evidence suggests that neuronal enriched endosomal protein of 21 kDa (NEEP21) takes part in facilitating transport of AMPA receptors…”
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Protein trafficking, targeting, and interaction at the glutamate synapse by Davanger, S, Manahan-Vaughan, D, Mulle, C, Storm-Mathisen, J, Ottersen, O.P

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Cellular and subcellular expression of monocarboxylate transporters in the pigment epithelium and retina of the rat by Bergersen, L, Jóhannsson, E, Veruki, M.L, Nagelhus, E.A, Halestrap, A, Sejersted, O.M, Ottersen, O.P

“…The cellular and subcellular expression of the monocarboxylate transporters MCT1, MCT2 and MCT4 [corresponding to MCT3 of Price N. T. et al. (1998) Biochem. J…”
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Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum by Ottersen, O P, Zhang, N, Walberg, F

“…An electron microscopic, double-labelling immunocytochemical procedure was used to assess the level of fixed glutamate and glutamine in different cell profiles…”
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The distribution of inhibitory and excitatory synapses on single, reconstructed jaw-opening motoneurons in the cat by Shigenaga, Y., Moritani, M., Oh, S.J., Park, K.P., Paik, S.K., Bae, J.Y., Kim, H.N., Ma, S.K., Park, C.W., Yoshida, A., Ottersen, O.P., Bae, Y.C.

“…In a previous study, we reported that the distribution of inhibitory input, in contrast to excitatory input, decreased somatofugally along dendrites of cat…”
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Postembedding light- and electron microscopic immunocytochemistry of amino acids: description of a new model system allowing identical conditions for specificity testing and tissue processing by OTTERSEN, O. P

“…Specificity testing should be performed under conditions identical to or closely similar to those of the immunocytochemical procedure. This paper describes a…”
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