Search Results - "Otten, U."

Interleukin-6 (IL-6)—A molecule with both beneficial and destructive potentials by Gadient, Reto A., Otten, Uwe H.

“…Interleukin-6 (IL-6), a member of the neuropoietic cytokine family, initially was described in terms of its activities in the immune system and during…”
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Age-dependent time course of cerebral brain-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 in APP23 transgenic mice by Schulte-Herbrüggen, O., Eckart, S., Deicke, U., Kühl, A., Otten, U., Danker-Hopfe, H., Abramowski, D., Staufenbiel, M., Hellweg, R.

“…Neurotrophins, including brain‐derived neurotrophic factor (BDNF), nerve growth factor (NGF), and neurotrophin‐3 (NT‐3), have repeatedly been shown to be…”
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Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development by Gadient, R A, Otten, U

“…Using RT-PCR, the development profile of interleukin-6 (IL-6) and its receptor (IL-6R) mRNAs in rat brain was investigated. Our results indicate that IL-6 and…”
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GABAB receptor expression and cellular localization in gerbil hippocampus after transient global ischemia by VOLLENWEIDER, F, BENDFELDT, K, MAETZLER, W, OTTEN, U, NITSCH, C

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Interleukin-6 (IL-6) and its soluble receptor support survival of sensory neurons by Thier, M., März, P., Otten, U., Weis, J., Rose-John, S.

“…The cytokine interleukin‐6 (IL‐6) has multiple functions in the immune and hematopoietic systems. IL‐6 is related to ciliary neurotrophic factor (CNTF), a…”
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Nerve Growth Factor Induces Growth and Differentiation of Human B Lymphocytes by Otten, Uwe, Ehrhard, Patricia, Peck, Richard

“…Nerve growth factor (NGF) is known to affect peripheral sympathetic and sensory neurons as well as defined populations of neurons in the central nervous…”
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Expression of Nerve Growth Factor and Nerve Growth Factor Receptor Tyrosine Kinase Trk in Activated CD4-Positive T-Cell Clones by Ehrhard, Patricia B., Erb, Peter, Graumann, Ursula, Otten, Uwe

“…Recent evidence suggests that nerve growth factor (NGF), in addition to its neurotrophic functions, acts as an immunomodulator mediating "cross-talk" between…”
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Cytokines and Neurotrophins Interact in Normal and Diseased States by OTTEN, U., MÄRZ, P., HEESE, K., HOCK, C., KUNZ, D., ROSE-JOHN, S.

“…: Neurotrophins (NTs) such as nerve growth factor (NGF) as well as cytokines, for example, interleukin‐6 (IL‐6), are communicators between the nervous and…”
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An enzyme-linked immunoassay for nerve growth factor (NGF): a tool for studying regulatory mechanisms involved in NGF production in brain and in peripheral tissues by Weskamp, G, Otten, U

“…A sensitive enzyme-linked immunosorbent assay (ELISA) for nerve growth factor (NGF) has been developed. The sensitivity of this assay (0.1 pg/well) permits the…”
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β-amyloid modulates tyrosine kinase B receptor expression in SHSY5Y neuroblastoma cells: influence of the antioxidant melatonin by Olivieri, G, Otten, U, Meier, F, Baysang, G, Dimitriades-Schmutz, B, Müller-Spahn, F, Savaskan, E

“…Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in humans and is characterized by neuronal loss, neurofibrillary tangles and β-amyloid…”
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Multiple sclerosis patients express increased levels of beta-nerve growth factor in cerebrospinal fluid by Laudiero, L B, Aloe, L, Levi-Montalcini, R, Buttinelli, C, Schilter, D, Gillessen, S, Otten, U

“…We describe the measurement of beta-nerve growth factor (NGF) content in cerebrospinal fluid (CSF) from multiple sclerosis (MS) patients compared with CSF from…”
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Expression of Functional trk Protooncogene in Human Monocytes by Ehrhard, Patricia B., Ganter, Ursula, Bauer, Joachim, Otten, Uwe

“…There is increasing evidence that neurotrophins, including nerve growth factor (NGF), exert specific effects on cells of the immune system in addition to their…”
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Identification of interleukin-6 (IL-6)-expressing neurons in the cerebellum and hippocampus of normal adult rats by Gadient, R A, Otten, U

“…The cellular source of interleukin-6 (IL-6) in brain has not been identified. Using a sensitive, non-radioactive in situ hybridization technique, the cellular…”
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Increased cerebrospinal fluid levels of neurotrophin 3 (NT-3) in elderly patients with major depression by HOCK, C, HEESE, K, MÜLLER-SPAHN, F, HUBER, P, RIESEN, W, NITSCH, R. M, OTTEN, U

“…Neurotrophin 3 (NT-3) is a member of the neurotrophin gene family which supports the survival of specific neurons. NT-3 was shown to prevent the death of adult…”
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Increased CSF levels of nerve growth factor in patients with Alzheimer's disease by HOCK, C, HEESE, K, MÜLLER-SPAHN, F, HUBER, P, RIESEN, W, NITSCH, R. M, OTTEN, U

“…The authors quantitated CSF levels of nerve growth factor (NGF) in patients with AD, nondemented control subjects (CTR), and age-matched patients with major…”
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Basophil priming by neurotrophic factors. Activation through the trk receptor by Burgi, B, Otten, UH, Ochensberger, B, Rihs, S, Heese, K, Ehrhard, PB, Ibanez, CF, Dahinden, CA

“…There is increasing evidence that nerve growth factor (NGF) acts on cells of the immune system, apart from its neurotrophic effects. In human basophils, NGF…”
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Increased levels of NGF in sera of systemic lupus erythematosus patients by Bracci-Laudiero, L, Aloe, L, Levi-Montalcini, R, Galeazzi, M, Schilter, D, Scully, J L, Otten, U

“…Using a specific enzyme-linked immunosorbent assay (ELISA) for human nerve growth factor (NGF), serum levels in patients with systemic lupus erythematosus…”
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Postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in rat sympathetic and sensory ganglia by Gadient, R.A., Otten, U.

“…The postnatal expression of interleukin-6 (IL-6) and IL-6 receptor (IL-6R) mRNAs in superior cervical ganglia (SCG) and dorsal root ganglia (DRG) of normal…”
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Neurotrophins and cytokines--intermediaries between the immune and nervous systems by Otten, U, Gadient, R A

“…Neurotrophins (NTs), including nerve growth factor (NGF), are multifunctional: in addition to their well-characterized neurotrophic functions they are known to…”
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Differential expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat hypothalamus by Gadient, R A, Otten, U

“…Using the sensitive technique of reverse transcription followed by polymerase chain reaction (RT-PCR), the expression of interleukin-6 (IL-6) and its receptor…”
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