Search Results - "Ott, John L"

Orally absorbable cephalosporin antibiotics. 2. Structure-activity studies of bicyclic glycine derivatives of 7-aminodeacetoxycephalosporanic acid by Kukolja, Stjepan, Draheim, Susan E, Graves, Bernard J, Hunden, David C, Pfeil, Janice L, Cooper, Robin D. G, Ott, John L, Counter, Fred T

“…Three positional analogues (4-, 5-, and 7-) of benzothienylglycine and (N-acetylindolinyl)-5-glycine were prepared and coupled to…”
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Oral absorption of cephalosporin antibiotics. 1. Synthesis, biological properties and oral bioavailability of 7-arylacetamido-3-chloro cephalosporins in animals by Kukolja, Stjepan, Wright, Walter E, Quay, John F, Pfeil-Doyle, Janice, Draheim, Susan E, Eudaly, Judith Ann, Johnson, Roderick J, Ott, John L, Counter, Fred T

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Lack of Correlation Between β-Lactamase Production and Susceptibility to Cefamandole or Cefoxitin Among Spontaneous Mutants of Enterobacteriaceae by Ott, J L, Turner, J R, Mahoney, D F

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Chemistry of cephalosporin antibiotics. 28. Preparation and biological activity of 3-(substituted)vinyl cephalosporins by Webber, J. Alan, Ott, John L, Vasileff, Robert T

“…3-(Substituted)vinylcephem nuclei have been prepared by the reaction of 3-formylcephem derivatives with stabilized phosphoranes. Appropriate synthetic steps…”
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Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: the synthesis and evaluation of daptomycin (LY146032) by Debono, M, Abbott, B J, Molloy, R M, Fukuda, D S, Hunt, A H, Daupert, V M, Counter, F T, Ott, J L, Carrell, C B, Howard, L C

“…The novel lipopeptide antibiotic A21978C complex is active against Gram-positive organisms. This complex consists of a common peptide nucleus with various…”
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Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives by Debono, M, Willard, K E, Kirst, H A, Wind, J A, Crouse, G D, Tao, E V, Vicenzi, J T, Counter, F T, Ott, J L, Ose, E E

“…A series of 20-deoxo-20-cyclic (alkylamino) derivatives of tylosin, desmycosin, macrocin and lactenocin was prepared by reductive amination of the C-20…”
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Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics by Kirst, Herbert A, Toth, John E, Debono, Manuel, Willard, Kevin E, Truedell, Brenda A, Ott, John L, Counter, Fred T, Felty-Duckworth, Anna M, Pekarek, Robert S

“…Modification of the aldehyde group in tylosin and related macrolide antibiotics dramatically enhanced the oral efficacy of the derivatives against experimental…”
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Oral absorption of cephalosproin antibiotics 2. Expanded structure-activity relationships of 7-arylacetamido-3-substituted cephalosporins by Pfeil-Doyle, Janice, Draheim, Susan E, Kukolja, Stjepan, Ott, John L, Counter, Fred T

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Orally absorbable cephalosporin antibiotics. 3. Preparation of biologically active R-isomer of 7-(3-benzothienylglycylamido)deacetoxycephalosporanic acid by Kukolja, Stjepan, Pfeil, Janice L, Draheim, Susan E, Ott, John L

“…The methyl and isopropyl esters of (RS)-3-benzothienylglycine were resolved with (+)- and (-)-tartaric acid in acetonitrile to give the corresponding R and S…”
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Examination of model enzyme and penetration systems in relation to antibacterial activity by Boyd, D B, Ott, J L

“…Recent work has shown that the activity of cephalosporins in inhibiting exocellular DD-peptidases from Streptomyces R61 and Actinomadura R39 are, at best, only…”
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The synthesis and biological evaluation of some novel aminoheterocyclic methoxime monobactam derivatives by Wheeler, W J, Finley, D R, Ott, J L

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Formation of adenosine by cell-free extracts of Escherichia coli by OTT, J L, WERKMAN, C H

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Coupled nucleoside phosphorylase reactions in Escherichia coli by OTT, J L, WERKMAN, C H

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ASPARAGINASE FROM MYCOBACTERIA12 by Ott, John L.

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Synthesis and biological evaluation of a series of parenteral 3'-quaternary ammonium cephalosporins by Brown, Raymond F, Kinnick, Michael D, Morin, John M, Vasileff, Robert T, Counter, Fred T, Davidson, Edward O, Ensminger, Paul W, Eudaly, Judith A, Kasher, Jeffrey S

“…The preparation and biological evaluation of a series of 7 beta-[2-(2-aminothiazol-4-yl)-2(Z)-methoximinoacetamido]cep halosporins, substituted at the…”
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Synthesis and structure-activity relationships of new 9-N-alkyl derivatives of 9(S)-erythromycylamine by Kirst, Herbert A, Wind, Julie A, Leeds, James P, Willard, Kevin E, Debono, Manuel, Bonjouklian, Rosanne, Greene, James M, Sullivan, Kevin A, Paschal, Jonathan W

“…A series of new 9-N-alkyl derivatives of 9(S)-erythromycylamine has been synthesized by reductive alkylation of erythromycylamine with aliphatic aldehydes and…”
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Oral absorption of cephalosporin antibiotics. 2. Expanded structure-activity relationships of 7-(arylacetamido)-3-substituted cephalosporins by Pfeil-Doyle, J, Draheim, S E, Kukolja, S, Ott, J L, Counter, F T

“…The structure-activity relationship for 7-arylacetamido cephalosporins has been extended. Modifications of the 7-aryl group led to improvements in…”
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Oral absorption of cephalosporin antibiotics. 1. Synthesis, biological properties, and oral bioavailability of 7-(arylacetamido)-3-chloro cephalosporins in animals by Kukolja, S, Wright, W E, Quay, J F, Pfeil-Doyle, J, Draheim, S E, Eudaly, J A, Johnson, R J, Ott, J L, Counter, F T, Cooper, R D

“…A number of 7-(arylacetamido)-3-substituted cephalosporins were prepared and tested in animals for oral absorbability. Bioavailability in mice, rats, dogs, and…”
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Asparaginase from mycobacteria by OTT, J L

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