Search Results - "Otsuki, Yuji"

Glutaminolysis‐related genes determine sensitivity to xCT‐targeted therapy in head and neck squamous cell carcinoma by Okazaki, Shogo, Umene, Kiyoko, Yamasaki, Juntaro, Suina, Kentaro, Otsuki, Yuji, Yoshikawa, Momoko, Minami, Yushi, Masuko, Takashi, Kawaguchi, Sho, Nakayama, Hideki, Banno, Kouji, Aoki, Daisuke, Saya, Hideyuki, Nagano, Osamu

“…Targeting the function of membrane transporters in cancer stemlike cells is a potential new therapeutic approach. Cystine‐glutamate antiporter xCT expressed in…”
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MEK inhibition suppresses metastatic progression of KRAS‐mutated gastric cancer by Yamasaki, Juntaro, Hirata, Yuki, Otsuki, Yuji, Suina, Kentaro, Saito, Yoshiyuki, Masuda, Kenta, Okazaki, Shogo, Ishimoto, Takatsugu, Saya, Hideyuki, Nagano, Osamu

“…Metastatic progression of tumors is driven by genetic alterations and tumor‐stroma interaction. To elucidate the mechanism underlying the oncogene‐induced…”
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Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT‐targeted therapy by Otsuki, Yuji, Yamasaki, Juntaro, Suina, Kentaro, Okazaki, Shogo, Koike, Naoyoshi, Saya, Hideyuki, Nagano, Osamu

“…The major cellular antioxidant glutathione (GSH) protects cancer cells from oxidative damage that can lead to the induction of ferroptosis, an iron‐dependent…”
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Identification of kit-ligand a as the Gene Responsible for the Medaka Pigment Cell Mutant few melanophore by Otsuki, Yuji, Okuda, Yuki, Naruse, Kiyoshi, Saya, Hideyuki

“…The body coloration of animals is due to pigment cells derived from neural crest cells, which are multipotent and differentiate into diverse cell types. Medaka…”
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MEK inhibition preferentially suppresses anchorage‐independent growth in osteosarcoma cells and decreases tumors in vivo by Shimizu, Takatsune, Kimura, Kiyomi, Sugihara, Eiji, Yamaguchi‐Iwai, Sayaka, Nobusue, Hiroyuki, Sampetrean, Oltea, Otsuki, Yuji, Fukuchi, Yumi, Saitoh, Kaori, Kato, Keiko, Soga, Tomoyoshi, Muto, Akihiro, Saya, Hideyuki

“…Osteosarcoma is the most common high‐grade malignancy of bone, and novel therapeutic options are urgently required. Previously, we developed mouse osteosarcoma…”
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Midline Extraperitoneal Approach for Obturator Hernia Repair by Otsuki, Yuji, Konn, Hirofumi, Takeda, Keisa, Koike, Masahiko

“…Obturator hernia (OH) is a rare condition that accounts for 0.073–1% of abdominal hernias and 0.48% of bowel obstructions. OH frequently occurs in elderly…”
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Emergent high-Tc ferroelectric ordering of strongly correlated and frustrated protons in a heteroepitaxial ice film by Sugimoto, Toshiki, Aiga, Norihiro, Otsuki, Yuji, Watanabe, Kazuya, Matsumoto, Yoshiyasu

“…Materials containing strong correlation and frustration have the potential to respond to external perturbations in an unusual way. In the case of common water…”
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Outcomes, safety, and feasibility of video-assisted thoracic surgery in lung cancer patients on hemodialysis: a case series by Otsuki, Yuji, Kuwahara, Hiroaki, Konn, Hirofumi

“…Objective The rate of surgical resection of lung cancer in patients on hemodialysis is expected to increase due to the development of hemodialysis, improved…”
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Prospects for new lung cancer treatments that target EMT signaling by Otsuki, Yuji, Saya, Hideyuki, Arima, Yoshimi

“…Lung cancer is the most common cancer worldwide. Treatment options for lung cancer include surgery, radiation therapy, chemotherapy, molecularly targeted…”
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Abstract 2019: Drug repositioning to induce the synthetic lethality in cancer cells with GSH-depleting therapy by Otsuki, Yuji, Nagano, Osamu, Saya, Hideyuki

“…Abstract The major cellular antioxidant glutathione (GSH) protects cancer cells from oxidative damage that can lead to the induction of ferroptosis. Inhibitor…”
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Emergent high-T sub(c) ferroelectric ordering of strongly correlated and frustrated protons in a heteroepitaxial ice film by Sugimoto, Toshiki, Aiga, Norihiro, Otsuki, Yuji, Watanabe, Kazuya, Matsumoto, Yoshiyasu

“…Materials containing strong correlation and frustration have the potential to respond to external perturbations in an unusual way. In the case of common water…”
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Establishment and Characterization of a New Lung Cancer Cell Line (MI‐4) Producing High Levels of Granulocyte Colony Stimulating Factor by Harada, Ryoji, Uemura, Yoshiki, Kobayashi, Makoto, Zamecnikova, Adriana, Nakata, Hideshi, Taguchi, Takahiro, Furihata, Mutsuo, Otsuki, Yuji, Taguchi, Hirokuni

“…We established a human lung cancer cell line, MI‐4 from the pleural effusion of a 69‐year‐old male with advanced large cell undifferentiated carcinoma of the…”
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Abstract 4639: SLC7A11 expression confers cancer stem-like properties in small cell lung cancer cells by Kamenori, Shohei, Suina, Kentaro, Yamasaki, Juntaro, Shintani, Subaru, Otsuki, Yuji, Hirata, Yuki, Okazaki, Shogo, Tsuchihashi, Kenji, Sampetrean, Oltea, Mitsuishi, Yoichiro, Takahashi, Fumiyuki, Takahashi, Kazuhisa, Saya, Hideyuki, Nagano, Osamu

“…Abstract Small Cell Lung Cancer (SCLC) which accounts for 15 % of primary lung cancers is known to grow fast and metastasize easily to whole body at early…”
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Abstract 1254: Integration of human omics analysis and new syngeneic tumor organoid models reveals that aberrant RAS/PI3K crosstalk triggers refractoriness in high-grade serous carcinoma by Tamura, Tomohiro, Masuda, Kenta, Nagai, Shimpei, Imaeda, Keiyo, Yamasaki, Juntaro, Sugihara, Eiji, Nobusue, Hiroyuki, Otsuki, Yuji, Yamaguchi, Rui, Sakurada, Kazuhiro, Yamagami, Wataru, Saya, Hideyuki, Nagano, Osamu

“…Abstract Refractory high-grade serous carcinoma (HGSC) is one of the most severe clinical problems in gynecology, but we have barely grasped the underlying…”
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A case of spindle cell carcinoma of the penis by Shimamoto, Tsutomu, Iiyama, Tatsuo, Karashima, Takashi, Inoue, Keiji, Shuin, Taro, Matsumoto, Manabu, Otsuki, Yuji

“…Spindle cell carcinoma of the penis is extremely rare. The present case report is the nineth case in the world literature. A 71-year-old man was referred to…”
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A case of localized solitary microscopic honeycombing in the lung : An unusual appearance on CT by MURATA, Y, INOMATA, T, OTSUKI, Y, HAMAGUCHI, K, YOSHIDA, S

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