Search Results - "Otsuka, Kuniko"

Predictive Evaluation of Pharmaceutical Properties of Ulinastatin-Containing Vaginal Suppositories as a Hospital Preparation by Near-Infrared Spectroscopy by Kishino, Tohru, Inoue, Yoshihiro, Inoue, Kayoko, Saito, Kenichi, Kondo, Masami, Otsuka, Kuniko, Terukina, Takayuki, Hattori, Yusuke, Otsuka, Makoto

“…A vaginal suppository containing ulinastatin (UTI) was developed as a hospital pharmacy product from UTI injection solution and Witepsol® S-55. After mixing at…”
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Non-destructive prediction of the drug content of an acetaminophen suppository by near-infrared spectroscopy and X-ray computed tomography by Otsuka, Kuniko, Uchino, Tomohiro, Otsuka, Makoto

“…Abstract The purpose of this study is to develop non-destructive methods to determine the drug content of suppositories using near-infrared (NIR) spectrometry…”
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Application of NIR spectroscopy for the quality control of mangosteen pericarp powder: quantitative analysis of alpha-mangostin in mangosteen pericarp powder and capsule by Peerapattana, Jomjai, Otsuka, Kuniko, Otsuka, Makoto

“…Near-infrared spectroscopy (NIR) was applied to the quantitative analysis of the concentration of alpha-mangostin (aM) in mangosteen pericarp powder (MP). The…”
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Chemoinformetrical evaluation of dissolution property of indomethacin tablets by near-infrared spectroscopy by Otsuka, Makoto, Tanabe, Hideaki, Osaki, Kazuo, Otsuka, Kuniko, Ozaki, Yukihiro

“…The purpose of this study was to use near-infrared spectrometry (NIR) with chemoinformetrics to predict the change of dissolution properties in indomethacin…”
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Quantitative Evaluation of the Disintegration of Orally Rapid Disintegrating Tablets by X-Ray Computed Tomography by Otsuka, Makoto, Yamanaka, Azusa, Uchino, Tomohiro, Otsuka, Kuniko, Sadamoto, Kiyomi, Ohshima, Hiroyuki

“…To measure the rapid disintegration of Oral Disintegrating Tablets (ODT), a new test (XCT) was developed using X-ray computing tomography (X-ray CT). Placebo…”
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Pharmaceutical evaluation of hospital-prepared, ulinastatin-containing vaginal suppositories by Kishino, Tohru, Inoue, Yoshihiro, Inoue, Kayoko, Saito, Kenichi, Kondo, Masami, Otsuka, Kuniko, Terukina, Takayuki, Hattori, Yusuke, Otsuka, Makoto

“…Ulinastatin (UTI) is a trypsin inhibitor derived from human urine. UTI has inhibitory activities against many enzymes, and is clinically effective and safe for…”
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Efficacy of the injectable calcium phosphate ceramics suspensions containing magnesium, zinc and fluoride on the bone mineral deficiency in ovariectomized rats by Otsuka, Makoto, Oshinbe, Ayako, Legeros, Racquel Z, Tokudome, Yoshihiro, Ito, Atsuo, Otsuka, Kuniko, Higuchi, William I

“…The purpose of this study was to evaluate the therapeutic efficacy of a new calcium phosphate (CaP)-based formulation in improving the bone mineral deficiency…”
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Effect of geometrical structure on the in vivo quality change of a three-dimensionally perforated porous bone cell scaffold made of apatite/collagen composite by Otsuka, Makoto, Nakagawa, Hidenori, Otsuka, Kuniko, Ito, Atsuo, Higuchi, William I.

“…Biodegradable artificial bone blocks with interconnective pores were prepared using a self‐setting apatite/collagen composite cement as a cell scaffold for…”
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Partial Least Square Discriminant Analysis of Mangosteen Pericarp Powder by near Infrared Spectroscopy by Peerapattana, Jomjai, Shinzawa, Hideyuki, Otsuka, Kuniko, Hattori, Yusuke, Otsuka, Makoto

“…Partial least square discriminant analysis (PLS-DA) was applied to sort out the difference between mangosteen powder and fake samples measured by near infrared…”
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Theoretical Analysis of Tablet Hardness Prediction Using Chemoinformetric Near-Infrared Spectroscopy by TANABE, Hideaki, OTSUKA, Kuniko, OTSUKA, Makoto

“…In order to clarify the theoretical basis of the variability in the measurement of tablet hardness by compression pressure, NIR spectroscopic methods were used…”
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Comparative evaluation of bioactivity change of crystalline trypsin during compression by chemoinformatics and 2-D Fourier-transform infrared spectroscopy by Otsuka, Makoto, Fukui, Yuya, Otsuka, Kuniko, Ozaki, Yukihiro

“…The purpose of this study is to develop a method of evaluating the enzymatic activity of trypsin in a solid-state based on Fourier transform infrared (FT-IR)…”
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Effect of nanostructure on biodegradation behaviors of self-setting apatite/collagen composite cements containing vitamin K2 in rats by Otsuka, Makoto, Kuninaga, Tomoaki, Otsuka, Kuniko, Higuchi, William I.

“…Apatite cement and collagen were combined by a mechanochemical method to create a new self‐setting apatite/collagen composite cement, and menatetrenone (VK2)…”
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Determination of Cephalexin Crystallinity and Investigation of Formation of its Amorphous Solid by Chemoinformetrical near Infrared Spectroscopy by Otsuka, Makoto, Fukui, Yuya, Otsuka, Kuniko, Kim, Hyo-Jin, Ozaki, Yukihiro

“…The crystallinity of cephalexin (CEX) was evaluated by chemoinformetrical near infrared (NIR) spectroscopy. The molecular interaction of ground amorphous solid…”
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Quantitative analysis of α-mangostin in hydrophilic ointment using near-infrared spectroscopy by Peerapattana, Jomjai, Otsuka, Kuniko, Hattori, Yusuke, Otsuka, Makoto

“…Abstract The objective of this research was to quantify the α-mangostin content in mangosteen pericarp (MP) ointment as a colloidal dispersion using…”
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Therapeutic effect of zinc-containing calcium phosphate suspension injection in thermal burn-rats by Otsuka, Makoto, Shikamura, Masayuki, Otsuka, Kuniko, Sogo, Yu, Ito, Atsuo

“…The aim of this study was to evaluate the efficacy of suspensions of zinc‐containing tricalcium phosphate (TCP) in the healing of thermal burns in rats…”
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Effect of compression temperature on the consolidation mechanism of chlorpropamide polymorphs by Otsuka, M, Matsumoto, T, Higuchi, S, Otsuka, K, Kaneniwa, N

“…The effect of environmental temperature on the compression mechanism of chlorpropamide (CPM) polymorph, forms A and C, was investigated with an eccentric type…”
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Therapeutic effects of transdermal systems containing zinc-related materials on thermal burn rats by Otsuka, Makoto, Hatakeyama, Haruna, Shikamura, Masayuki, Otsuka, Kuniko, Ito, Atsuo

“…The aim of the present study is to evaluate the efficacy of slow zinc (Zn) release from β-tricalcium phosphate powder (ZnTCP) containing 10 mol% Zn on rats…”
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Effect of geometric factors on hydration kinetics of theophylline anhydrate tablets by Otsuka, M, Kaneniwa, N, Otsuka, K, Kawakami, K, Umezawa, O, Matsuda, Y

“…The effect of tablet thickness on the hydration kinetics of types I and II theophylline anhydrate tablets at 95% relative humidity and 35 degrees C was studied…”
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Effect of nanostructure on biodegradation behaviors of self‐setting apatite/collagen composite cements containing vitamin K 2 in rats by Otsuka, Makoto, Kuninaga, Tomoaki, Otsuka, Kuniko, Higuchi, William I.

“…Apatite cement and collagen were combined by a mechanochemical method to create a new self‐setting apatite/collagen composite cement, and menatetrenone (VK2)…”
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Toward Freedom from Cancer Pain in Japan by Otsuka, Kuniko, Yasuhara, Hajime

“…Life expectancy in Japan is highest in the world. Cancer is the leading cause of mortality in Japan, accounting for about 30 percent of all deaths. Many…”
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