Search Results - "Otsuka, Hirotada"
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Histidine decarboxylase deficiency inhibits NBP-induced extramedullary hematopoiesis by modifying bone marrow and spleen microenvironments
Published in International journal of hematology (01-03-2021)“…Histidine decarboxylase (HDC), a histamine synthase, is expressed in various hematopoietic cells and is induced by hematopoietic cytokines such as granulocyte…”
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Dynamics of Platelet Behaviors as Defenders and Guardians: Accumulations in Liver, Lung, and Spleen in Mice
Published in Biological & pharmaceutical bulletin (01-08-2019)“…Systemic platelet behaviors in experimental animals are often assessed by infusion of isotope-labeled platelets and measuring them under anesthesia. However,…”
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3
Expressions of vascular endothelial growth factor receptors, Flk1 and Flt1, in rat skin mast cells during development
Published in Journal of Veterinary Medical Science (2020)“…Vascular endothelial growth factor-A (VEGF-A) is a principal regulator of hematopoiesis as well as angiogenesis. However, the functions of VEGF-A and its…”
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4
Symmetrical retrograde actin flow in the actin fusion structure is involved in osteoclast fusion
Published in Biology open (15-07-2017)“…The aim of this study was to elucidate the role of the zipper-like structure (ZLS), a podosome-related structure that transiently appears at the cell contact…”
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5
Regulation of Osteoclast Multinucleation by the Actin Cytoskeleton Signaling Network
Published in Journal of cellular physiology (01-02-2015)“…Although it is known that osteoclasts are multinucleated cells that are responsible for bone resorption, the mechanism by which their size is regulated is…”
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6
Decisive differences in the bone repair processes of the metaphysis and diaphysis in young mice
Published in Bone Reports (01-06-2018)“…Fractures are common traumatic injuries that mainly occur in the metaphyses of long bones such as the proximal humerus, distal radius, and proximal femur…”
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7
Changes in histidine decarboxylase expression influence extramedullary hematopoiesis in postnatal mice
Published in Anatomical record (Hoboken, N.J. : 2007) (01-05-2021)“…Histidine decarboxylase (HDC), histamine synthase, is expressed in hematopoietic stem cells and in lineage‐committed progenitors in the bone marrow (BM)…”
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8
Dynamics of Platelet Behaviors as Defenders and Guardians : Accumulations in Liver, Lung, and Spleen in Mice
Published in Biological and Pharmaceutical Bulletin (01-08-2019)“…Systemic platelet behaviors in experimental animals are often assessed by infusion of isotope-labeled platelets and measuring them under anesthesia. However,…”
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9
Big Insulin-like Growth Factor 2–Producing Tumor in a Hypoglycemic Dog
Published in Veterinary pathology (01-05-2020)“…A 10-year-old female Papillon dog that had previously developed a mammary tumor was admitted for treatment of a hypoglycemic attack. Blood examination showed…”
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10
Nitrogen-containing bisphosphonate induces a newly discovered hematopoietic structure in the omentum of an anemic mouse model by stimulating G-CSF production
Published in Cell and tissue research (01-02-2017)“…We previously reported that the injection of nitrogen-containing bisphosphonate (NBP) induced the site of erythropoiesis to shift from the bone marrow (BM) to…”
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11
In situ proliferation and differentiation of macrophages in dental pulp
Published in Cell and tissue research (01-10-2011)“…The presence of macrophages in dental pulp is well known. However, whether these macrophages proliferate and differentiate in the dental pulp in situ, or…”
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12
Pulmonary platelet accumulation induced by catecholamines: Its involvement in lipopolysaccharide-induced anaphylaxis-like shock
Published in International immunopharmacology (01-02-2017)“…Intravenously injected lipopolysaccharides (LPS) rapidly induce pulmonary platelet accumulation (PPA) and anaphylaxis-like shock (ALS) in mice. Macrophages…”
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13
Kupffer cells support extramedullary erythropoiesis induced by nitrogen-containing bisphosphonate in splenectomized mice
Published in Cellular immunology (2011)“…► We examined the change of erythropoiesis in the splenectomized mice by NBP treatment. ► In splenectomized mice, erythropoiesis moved to the liver without…”
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14
Roles of platelets and macrophages in the protective effects of lipopolysaccharide against concanavalin A-induced murine hepatitis
Published in Biochimica et biophysica acta (01-09-2011)“…Platelets are reportedly causal in hepatitis. We previously showed that in mice, lipopolysaccharide (LPS) induces a reversible and macrophage-dependent hepatic…”
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15
Comprehensive genetic exploration of selective tooth agenesis of mandibular incisors by exome sequencing
Published in Human genome variation (23-02-2017)“…Tooth agenesis is described as the absence of one or more teeth. It is caused by a failure in tooth development and is one of the most common human…”
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Analysis of periapical alveolar bone resorption after the removal of interdental wire ligation
Published in Pediatric dental journal (01-04-2015)“…Periapical bone resorption is mainly induced by inflammation resulting from an infected root canal. However, chemical and physical stimuli (e.g., traumatic…”
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17
Histological identification of cells directly participating calcified tissue resorption and destruction
Published in The FASEB journal (01-04-2017)“…Abstract only Introduction It is well established that multinucleated osteoclasts are the main cells to resorb calcified tissues. However, it still remains the…”
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18
Expression of type VI collagen α3 chain in canine mammary carcinomas
Published in Research in veterinary science (01-06-2023)“…This study aimed to investigate the expression of type VI collagen α3 chain (COL6a3) in neoplastic cells of canine mammary gland carcinomas (CMGCs) using…”
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Histamine deficiency inhibits lymphocyte infiltration in the submandibular gland of aged mice via increased anti-aging factor Klotho
Published in Journal of oral biosciences (01-09-2023)Get full text
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20
Expression of receptor-type tumour endothelial marker 8 in carcinoma cells showing luminal progenitor-like phenotypes in canine mammary gland carcinomas
Published in Journal of comparative pathology (01-01-2023)“…This study aimed to investigate the expression of receptor-type tumour endothelial marker 8 (TEM8RT) in canine mammary gland carcinomas (CMGCs) using…”
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