Search Results - "Otsuji, Mikiya"
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Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties
Published in Nature communications (30-01-2020)“…Tumor-associated macrophages affect tumor progression and resistance to immune checkpoint therapy. Here, we identify the chemokine signal regulator FROUNT as a…”
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Assessment of the relationship between central venous pressure waveform and the severity of tricuspid valve regurgitation using data science
Published in Scientific reports (22-10-2024)“…Purpose The relationship between the height of the V wave in the central venous pressure (CVP) waveform and the severity of tricuspid regurgitation (TR) is…”
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3
Tracking of intertissue migration reveals the origins of tumor-infiltrating monocytes
Published in Proceedings of the National Academy of Sciences - PNAS (27-05-2014)“…Myeloid cells such as monocytes and monocyte-derived macrophages promote tumor progression. Recent reports suggest that extramedullary hematopoiesis sustains a…”
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4
Comparison of leak fraction between the laryngeal mask airway and endotracheal tube during anesthesia: a single-center retrospective study
Published in Journal of anesthesia (01-08-2024)“…The use of the laryngeal mask airway (LMA), which offers the benefits of ease in insertion and prevention of tracheal damage, is associated with a risk of flow…”
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5
Quantitative relationship between anteriorization of alpha oscillations and level of general anesthesia
Published in Journal of clinical monitoring and computing (01-04-2023)“…A typical electroencephalogram (EEG) change induced by general anesthesia is anteriorization—disappearance of occipital alpha oscillations followed by the…”
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A mass conserved reaction-diffusion system captures properties of cell polarity
Published in PLoS computational biology (01-06-2007)“…Cell polarity is a general cellular process that can be seen in various cell types such as migrating neutrophils and Dictyostelium cells. The Rho small…”
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Reliability of cardiac output measurements using LiDCOrapid™ and FloTrac/Vigileo™ across broad ranges of cardiac output values
Published in Journal of clinical monitoring and computing (01-08-2017)“…Knowing a patient’s cardiac output (CO) could contribute to a safe, optimized hemodynamic control during surgery. Precise CO measurements can serve as a guide…”
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Quantitative evaluation of stress in Japanese anesthesiology residents based on heart rate variability and psychological testing
Published in Journal of clinical monitoring and computing (01-04-2020)“…Clinical anesthesiologists, particularly residents, work in stressful environments. However, evidence-based physiological and psychological tests to evaluate…”
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Reduced Supply of Monocyte-Derived Macrophages Leads to a Transition from Nodular to Diffuse Lesions and Tissue Cell Activation in Silica-Induced Pulmonary Fibrosis in Mice
Published in The American journal of pathology (01-11-2015)“…Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Lung macrophages have been reported to regulate both progression and remission of…”
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Transcriptome network analysis identifies protective role of the LXR/SREBP-1c axis in murine pulmonary fibrosis
Published in JCI insight (10-01-2019)“…Pulmonary fibrosis (PF) is an intractable disorder with a poor prognosis. Although lung fibroblasts play a central role in PF, the key regulatory molecules…”
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11
Temperature-dependent inotropic and lusitropic indices based on half-logistic time constants for four segmental phases in isovolumic left ventricular pressure-time curve in excised, cross-circulated canine heart
Published in Canadian journal of physiology and pharmacology (01-02-2017)“…Varying temperature affects cardiac systolic and diastolic function and the left ventricular (LV) pressure-time curve (PTC) waveform that includes information…”
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A conceptual molecular network for chemotactic behaviors characterized by feedback of molecules cycling between the membrane and the cytosol
Published in Science signaling (14-12-2010)“…Cell chemotaxis has been characterized as the formation of a front-back axis that is triggered by a gradient of chemoattractant; however, chemotaxis is…”
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Half-Logistic Function Model for First Half of Descending Phase of Cardiomyocyte Cytoplasmic Ca2+ Concentration ([Ca2+]i)-Time Curve (CaTCIII) in Isolated Aequorin-Injected Mouse Left Ventricular Papillary Muscle
Published in Acta Cardiologica Sinica (01-01-2016)“…Background: Myocardial contraction and relaxation are regulated by increases and decreases in cytoplasmic calcium concentration ([Ca2+]i). In previous studies,…”
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Half-Logistic Function Model for First Half of Descending Phase of Cardiomyocyte Cytoplasmic Ca^(2+) Concentration ([Ca^(2+)]_i)-Time Curve (CaTCIII) in Isolated Aequorin-Injected Mouse Left Ventricular Papillary Muscle
Published in Acta Cardiologica Sinica (01-01-2016)“…Myocardial contraction and relaxation are regulated by increases and decreases in cytoplasmic calcium concentration ([Ca(2+)]i). In previous studies, we found…”
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Calcium-induced calcium release from the sarcoplasmic reticulum can be evaluated with a half-logistic function model in aequorin-injected cardiac muscles
Published in Journal of anesthesia (01-12-2011)“…Purpose Release of calcium (Ca 2+ ) from the sarcoplasmic reticulum (SR) induced by Ca 2+ influx through voltage-dependent sarcolemmal L-type Ca 2+ channels…”
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Half-Logistic Time Constants as Inotropic and Lusitropic Indices for Four Sequential Phases of Isometric Tension Curves in Isolated Rabbit and Mouse Papillary Muscles
Published in International Heart Journal (2009)“…The waveforms of myocardial tension and left ventricular (LV) pressure curves are useful for evaluating myocardial and LV performance, and especially for…”
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Superior Logistic Model for Decay of Ca2+ Transient and Isometric Relaxation Force Curve in Rabbit and Mouse Papillary Muscles
Published in International Heart Journal (01-03-2007)“…A decrease in myocardial intracellular calcium concentration ([Ca2+]i) precedes relaxation, and a monoexponential function is typically used for fitting the…”
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18
Characterization of intracellular Ca2+ transient by the hybrid logistic function in aequorin-injected rabbit and mouse papillary muscles
Published in The journal of physiological sciences (2007)“…Myocardial intracellular calcium (Ca2+) transients (CaTs) regulate tension generation and relaxation. Isometric tension curves are often analyzed using…”
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Attenuation of phrenic nerve palsy associated with brachial plexus block by modified supra costal approach under fluoroscopic guidance
Published in Masui. The Japanese journal of anesthesiology (01-06-2010)“…Brachial plexus block (BPB) frequently accompanies phrenic nerve palsy (PNP). Thirty six patients scheduled for upper-limb surgery were allocated to 2 groups;…”
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Evaluation of cardiac and myocardial inotropism and lusitropism using half-logistic curve-fitting
Published in Masui. The Japanese journal of anesthesiology (01-04-2010)“…Half-logistic (h-L) function, which is half of the sigmoidal, logistic function with a boundary at the inflection point, curve-fits the isovolumic relaxation…”
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