Search Results - "Otoul, C."

Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study by Bretin, F., Bahri, M. A., Bernard, C., Warnock, G., Aerts, J., Mestdagh, N., Buchanan, T., Otoul, C., Koestler, F., Mievis, F., Giacomelli, F., Degueldre, C., Hustinx, R., Luxen, A., Seret, A., Plenevaux, A., Salmon, E.

“…Purpose [ 18 F]UCB-H is a novel radiotracer with a high affinity for synaptic vesicle glycoprotein 2A (SV2A), a protein expressed in synaptic vesicles. SV2A is…”
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Long-term continuation of levetiracetam in patients with refractory epilepsy by KRAKOW, Karsten, WALKER, M, OTOUL, C, SANDER, J. W. A. S

“…The long-term continuation (retention) rate, efficacy, and safety data of the new antiepileptic drug levetiracetam (LEV) was evaluated in all patients with…”
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Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsy by Otoul, Christian, Arrigo, Celestina, van Rijckevorsel, Kenou, French, Jacqueline A

“…Few comparative clinical trials of newer antiepileptic drugs (AEDs) in patients with refractory partial epilepsy are available. Therefore, meta-analysis is a…”
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Dose–response effect of levetiracetam 1000 and 2000 mg/day in partial epilepsy by Boon, P, Chauvel, P, Pohlmann-Eden, B, Otoul, C, Wroe, S

“…Purpose: To evaluate the efficacy, dose–response, tolerability, and withdrawal effects of levetiracetam (Keppra®) as adjunctive therapy in adult patients with…”
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Comparison of plasma and saliva concentrations of levetiracetam following administration orally as a tablet and as a solution in healthy adult volunteers by Lins, R L, Otoul, C, De Smedt, F, Coupez, R, Stockis, A

“…Concentrations in saliva, as an alternative to concentrations in blood, can be advantageous for the monitoring of antiepileptic agents. This study assesses the…”
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Evaluation of pharmacokinetic interaction between cetirizine and ritonavir, an HIV-1 protease inhibitor, in healthy male volunteers by PEYTAVIN, G, GAUTRAN, C, OTOUL, C, CREMIEUX, A. C, MOULAERT, B, DELATOUR, F, MELAC, M, STROLIN-BENEDETTI, M, FARINOTTI, R

“…Serious adverse effects have been observed with some non-sedative H1-antihistamines (terfenadine and astemizole) when they were associated with drugs known to…”
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Single-dose bioavailability of levetiracetam intravenous infusion relative to oral tablets and multiple-dose pharmacokinetics and tolerability of levetiracetam intravenous infusion compared with placebo in healthy subjects by Ramael, Steven, De Smedt, Florence, Toublanc, Nathalie, Otoul, Christian, Boulanger, Pierre, Riethuisen, Jean-Michel, Stockis, Armel

“…Background: Antiepileptic drugs are usually administere dorally, but alternative routes of drug delivery may be required when oral administration is not…”
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90 Safety, efficacy and transcriptional changes following repeated administration of dapirolizumab pegol in patients with systemic lupus erythematosus: results from a phase i study by Chamberlain, C, Colman, P, Ranger, A, Johnson, G, Otoul, C, Stach, C, Dörner, T, Urowitz, M, Hiepe, F

“…Background and aimsBinding of CD40 ligand (CD40L) to CD40 activates B cells, antigen-presenting cells and platelets. Evidence suggests CD40L blockade might…”
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Effect of levetiracetam on the pharmacokinetics of adjunctive antiepileptic drugs: A pooled analysis of data from randomized clinical trials by Gidal, Barry E., Baltès, Eugène, Otoul, Christian, Perucca, Emilio

“…The purpose of this study was to determine the influence of levetiracetam on the steady-state serum concentrations of other commonly used antiepileptic drugs…”
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PI-45Lack of interaction of levetiracetam with other antiepileptic drugs (AEDs) in children with epilepsy by OTOUL, C, DESMEDT, H, STOCKIS, A

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PI-45 by Otoul, C., De Smedt, H., Stockis, A.

“…BACKGROUND To assess levetiracetam (LEV) add‐on treatment effect on plasma concentrations of other antiepileptic drugs (AEDs) in paediatrics with epilepsy…”
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The effects of levetiracetam on objective and subjective sleep parameters in healthy volunteers and patients with partial epilepsy by Bell, Caroline, Vanderlinden, Hilde, Hiersemenzel, Reinhard, Otoul, Christian, Nutt, David, Wilson, Sue

“…Summary Levetiracetam is a novel antiepileptic drug which has recently been released as an adjunctive treatment for partial epilepsy. In the two studies…”
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Double-blind study to assess the efficacy of chlorproguanil given alone or in combination with chloroquine for malaria chemoprophylaxis in an area with Plasmodium falciparum resistance to chloroquine, pyrimethamine and cycloguanil by Coosemans, M H, Barutwanayo, M, Onori, E, Otoul, C, Gryseels, B, Wéry, M

“…In this study the efficacy of chlorproguanil (20 mg base weekly) was compared in schoolchildren with that of chloroquine (200 mg base weekly) and that of both…”
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PIII-81 by Ramael, S., Troenaru, M., Toublanc, N., Daoust, A., Otoul, C., Lu, Z., Stockis, A.

“…BACKGROUND The primary objective was to evaluate the safety, tolerability and pharmacokinetics of levetiracetam (LEV) administered intravenously at a higher…”
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PIII-81Levetiracetam intravenous infusion: A randomised placebo-controlled safety study by RAMAEL, S, TROENARU, M, TOUBLANC, N, DAOUST, A, OTOUL, C, LU, Z, STOCKIS, A

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