Search Results - "Otis, James"

Neuropathic Pain by Macone, Amanda, Otis, James A D

“…Neuropathic pain management is challenging, and typically requires a multifaceted approach. There are several treatment options, both pharmacologic and…”
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Reversal of Cocaine-Associated Synaptic Plasticity in Medial Prefrontal Cortex Parallels Elimination of Memory Retrieval by Otis, James M, Mueller, Devin

“…Addiction is characterized by abnormalities in prefrontal cortex that are thought to allow drug-associated cues to drive compulsive drug seeking and taking…”
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Heterogeneity in the Paraventricular Thalamus: The Traffic Light of Motivated Behaviors by McGinty, Jacqueline F, Otis, James M

“…The paraventricular thalamic nucleus (PVT) is highly interconnected with brain areas that control reward-seeking behavior. Despite this known connectivity,…”
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Prefrontal cortex output circuits guide reward seeking through divergent cue encoding by Otis, James M., Namboodiri, Vijay M. K., Matan, Ana M., Voets, Elisa S., Mohorn, Emily P., Kosyk, Oksana, McHenry, Jenna A., Robinson, J. Elliott, Resendez, Shanna L., Rossi, Mark A., Stuber, Garret D.

“…The prefrontal cortex is a critical neuroanatomical hub for controlling motivated behaviours across mammalian species 1 , 2 , 3 . In addition to intra-cortical…”
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Hormonal gain control of a medial preoptic area social reward circuit by McHenry, Jenna A, Otis, James M, Rossi, Mark A, Robinson, J Elliott, Kosyk, Oksana, Miller, Noah W, McElligott, Zoe A, Budygin, Evgeny A, Rubinow, David R, Stuber, Garret D

“…Social behaviors require neural circuits to process social cues and orchestrate motivational states. This study identifies a subpopulation of hypothalamic…”
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Myofascial Pain by Weller, Jason L, Comeau, Douglas, Otis, James A D

“…Myofascial pain syndromes arise from acute and chronic musculoskeletal pain and often have a referred neuropathic component. It affects more than three…”
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Social Stimuli Induce Activation of Oxytocin Neurons Within the Paraventricular Nucleus of the Hypothalamus to Promote Social Behavior in Male Mice by Resendez, Shanna L, Namboodiri, Vijay Mohan K, Otis, James M, Eckman, Louisa E H, Rodriguez-Romaguera, Jose, Ung, Randall L, Basiri, Marcus L, Kosyk, Oksana, Rossi, Mark A, Dichter, Gabriel S, Stuber, Garret D

“…Oxytocin (OT) is critical for the expression of social behavior across a wide array of species; however, the role of this system in the encoding of socially…”
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Noradrenergic regulation of fear and drug-associated memory reconsolidation by Otis, James M, Werner, Craig T, Mueller, Devin

“…Emotional and traumatic experiences lead to the development of particularly strong memories that can drive neuropsychiatric disorders, such as posttraumatic…”
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Obesity remodels activity and transcriptional state of a lateral hypothalamic brake on feeding by Rossi, Mark A, Basiri, Marcus L, McHenry, Jenna A, Kosyk, Oksana, Otis, James M, van den Munkhof, Hanna E, Bryois, Julien, Hübel, Christopher, Breen, Gerome, Guo, Wilson, Bulik, Cynthia M, Sullivan, Patrick F, Stuber, Garret D

“…The current obesity epidemic is a major worldwide health concern. Despite the consensus that the brain regulates energy homeostasis, the neural adaptations…”
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Visualization of cortical, subcortical and deep brain neural circuit dynamics during naturalistic mammalian behavior with head-mounted microscopes and chronically implanted lenses by Resendez, Shanna L, Jennings, Josh H, Ung, Randall L, Namboodiri, Vijay Mohan K, Zhou, Zhe Charles, Otis, James M, Nomura, Hiroshi, McHenry, Jenna A, Kosyk, Oksana, Stuber, Garret D

“…This protocol describes how to use miniature, integrated microscopes in conjunction with an implantable microendoscopic lens to guide light into and out of the…”
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Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models by Guo, Jiami, Otis, James M., Suciu, Sarah K., Catalano, Christy, Xing, Lei, Constable, Sandii, Wachten, Dagmar, Gupton, Stephanie, Lee, Janice, Lee, Amelia, Blackley, Katherine H., Ptacek, Travis, Simon, Jeremy M., Schurmans, Stephane, Stuber, Garret D., Caspary, Tamara, Anton, E.S.

“…Appropriate axonal growth and connectivity are essential for functional wiring of the brain. Joubert syndrome-related disorders (JSRD), a group of ciliopathies…”
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Primary Cilia Signaling Shapes the Development of Interneuronal Connectivity by Guo, Jiami, Otis, James M., Higginbotham, Holden, Monckton, Chase, Cheng, JrGang, Asokan, Aravind, Mykytyn, Kirk, Caspary, Tamara, Stuber, Garret D., Anton, E.S.

“…Appropriate growth and synaptic integration of GABAergic inhibitory interneurons are essential for functional neural circuits in the brain. Here, we…”
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Neurobiological dissociation of retrieval and reconsolidation of cocaine-associated memory by Otis, James M, Dashew, Kidane B, Mueller, Devin

“…Drug use is provoked by the presentation of drug-associated cues, even following long periods of abstinence. Disruption of these learned associations would…”
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Single-cell activity tracking reveals that orbitofrontal neurons acquire and maintain a long-term memory to guide behavioral adaptation by Namboodiri, Vijay Mohan K., Otis, James M., van Heeswijk, Kay, Voets, Elisa S., Alghorazi, Rizk A., Rodriguez-Romaguera, Jose, Mihalas, Stefan, Stuber, Garret D.

“…Learning to predict rewards based on environmental cues is essential for survival. The orbitofrontal cortex (OFC) contributes to such learning by conveying…”
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Paraventricular Thalamus Projection Neurons Integrate Cortical and Hypothalamic Signals for Cue-Reward Processing by Otis, James M., Zhu, ManHua, Namboodiri, Vijay M.K., Cook, Cory A., Kosyk, Oksana, Matan, Ana M., Ying, Rose, Hashikawa, Yoshiko, Hashikawa, Koichi, Trujillo-Pisanty, Ivan, Guo, Jiami, Ung, Randall L., Rodriguez-Romaguera, Jose, Anton, E.S., Stuber, Garret D.

“…The paraventricular thalamus (PVT) is an interface for brain reward circuits, with input signals arising from structures, such as prefrontal cortex and…”
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Infralimbic BDNF/TrkB enhancement of GluN2B currents facilitates extinction of a cocaine-conditioned place preference by Otis, James M, Fitzgerald, Michael K, Mueller, Devin

“…Brain-derived neurotrophic factor (BDNF) regulates synaptic activity and behavioral flexibility, and reduction of BDNF strongly predicts psychiatric disorders…”
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Inhibition of β-Adrenergic Receptors Induces a Persistent Deficit in Retrieval of a Cocaine-Associated Memory Providing Protection against Reinstatement by OTIS, James M, MUELLER, Devin

“…Drug-seeking behavior is maintained by encounters with drug-associated cues. Preventing retrieval of drug-associated memories that these cues provoke would…”
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A Paranigral VTA Nociceptin Circuit that Constrains Motivation for Reward by Parker, Kyle E., Pedersen, Christian E., Gomez, Adrian M., Spangler, Skylar M., Walicki, Marie C., Feng, Shelley Y., Stewart, Sarah L., Otis, James M., Al-Hasani, Ream, McCall, Jordan G., Sakers, Kristina, Bhatti, Dionnet L., Copits, Bryan A., Gereau, Robert W., Jhou, Thomas, Kash, Thomas J., Dougherty, Joseph D., Stuber, Garret D., Bruchas, Michael R.

“…Nociceptin and its receptor are widely distributed throughout the brain in regions associated with reward behavior, yet how and when they act is unknown. Here,…”
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Inhibition of Hippocampal β-Adrenergic Receptors Impairs Retrieval But Not Reconsolidation of Cocaine-Associated Memory and Prevents Subsequent Reinstatement by OTIS, James M, FITZGERALD, Michael K, MUELLER, Devin

“…Retrieval of drug-associated memories is critical for maintaining addictive behaviors, as presentation of drug-associated cues can elicit drug seeking and…”
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Increased Excitability and Synaptic Plasticity of Drd1- and Drd2-Expressing Prelimbic Neurons Projecting to Nucleus Accumbens after Heroin Abstinence Are Reversed by Cue-Induced Relapse and Protein Kinase A Inhibition by Kokane, Saurabh S, Cole, Robert D, Bordieanu, Bogdan, Ray, Chevin M, Haque, Ishraq A, Otis, James M, McGinty, Jacqueline F

“…Dysregulation of the input from the prefrontal cortex (PFC) to the nucleus accumbens (NAc) contributes to cue-induced opioid seeking but the heterogeneity in,…”
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