Search Results - "Otieno, Michael F."

Socio-demographic and sexual practices associated with HIV infection in Kenyan injection and non-injection drug users by Budambula, Valentine, Matoka, Charles, Ouma, James, Ahmed, Aabid A, Otieno, Michael F, Were, Tom

“…Substance use is increasingly becoming prevalent on the African continent, fueling the spread of HIV infection. Although socio-demographic factors influence…”
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CD4 T-cell expression of IFN-γ and IL-17 in pediatric malarial anemia by Raballah, Evans, Kempaiah, Prakasha, Karim, Zachary, Orinda, George O, Otieno, Michael F, Perkins, Douglas J, Ong'echa, John Michael

“…In Plasmodium falciparum holoendemic transmission regions of western Kenya, life-threatening pediatric malaria manifests primarily as severe malarial anemia…”
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Combining Evidence of Natural Selection with Association Analysis Increases Power to Detect Malaria-Resistance Variants by Ayodo, George, Price, Alkes L., Keinan, Alon, Ajwang, Arthur, Otieno, Michael F., Orago, Alloys S.S., Patterson, Nick, Reich, David

“…Statistical power to detect disease variants can be increased by weighting candidates by their evidence of natural selection. To demonstrate that this…”
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Polymorphic Variability in the Interleukin (IL)-1β Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1β Production by Ouma, Collins, Davenport, Gregory C., Awandare, Gordon A., Keller, Christopher C., Were, Tom, Otieno, Michael F., Vulule, John M., Martinson, Jeremy, Ong'echa, John M., Ferrell, Robert E., Perkins, Douglas J.

“…Interleukin (IL)-1β is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1β polymorphic…”
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Levels of CD16/Fcγ Receptor IIIA on CD14⁺ CD16⁺ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia than in Children with Cerebral or Uncomplicated Malaria by Ogonda, Lilian A, Orago, Alloys S.S, Otieno, Michael F, Adhiambo, Christine, Otieno, Walter, Stoute, José A

“…Fc gamma receptor IIIA (CD16/FcγRIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting…”
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Novel Functional Variant in the Stem Cell Growth Factor Promoter Protects against Severe Malarial Anemia by Ouma, Collins, Keller, Christopher C, Davenport, Gregory C, Were, Tom, Konah, Stephen, Otieno, Michael F, Hittner, James B, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J

“…Plasmodium falciparum malaria is a leading global cause of infectious disease burden. In areas in which P. falciparum transmission is holoendemic, such as…”
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Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production by Ouma, Collins, Davenport, Gregory C, Were, Tom, Otieno, Michael F, Hittner, James B, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J

“…Plasmodium falciparum malaria is one of the leading global causes of morbidity and mortality with African children bearing the highest disease burden. Among…”
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Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism by Were, Tom, Davenport, Gregory C., Yamo, Emmanuel O., Hittner, James B., Awandare, Gordon A., Otieno, Michael F., Ouma, Collins, Orago, Alloys S.S., Vulule, John M., Ong'echa, John M., Perkins, Douglas J.

“…Regulated upon activation, normal T-cell expressed, and secreted (RANTES, CCL-5) is an important immunoregulatory mediator that is suppressed in children with…”
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The levels of CD16/Fc gamma receptor III A on CD14+CD16+ monocytes are higher in children with severe Plasmodium falciparum anemia than in children with cerebral or uncomplicated malaria by Ogonda, Lilian A, Orago, Alloys SS, Otieno, Michael F, Adhiambo, Christine, Otieno, Walter, Stoute, José A

“…Background Fc gamma receptor IIIA (CD16/FCγRIIIA) on monocytes/macro-phages may play an important role in the pathogenesis of severe malarial anemia (SMA) by…”
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The Levels of CD16/Fc Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia than in Children with Cerebral or Uncomplicated Malaria by Ogonda, Lilian A, Orago, Alloys SS, Otieno, Michael F, Adhiambo, Christine, Otieno, Walter, Stoute, Jose A

“…Fc gamma receptor IIIA (CD16/FcRIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting…”
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Polymorphic variability in the IL-1β promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1β production by Ouma, Collins, Davenport, Gregory C., Awandare, Gordon A., Keller, Christopher C., Were, Tom, Otieno, Michael F., Vulule, John M., Martinson, Jeremy, Ong'echa, John M., Ferrell, Robert E., Perkins, Douglas J.

“…Interleukin (IL)-1β is a cytokine released as part of innate immune response to Plasmodium falciparum . Since the role of IL-1β polymorphic variability in…”
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Polymorphic variability in the interleukin (IL)-1beta promoter conditions susceptibility to severe malarial anemia and functional changes in IL-1beta production by Ouma, Collins, Davenport, Gregory C, Awandare, Gordon A, Keller, Christopher C, Were, Tom, Otieno, Michael F, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J

“…Interleukin (IL)-1beta is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1beta polymorphic…”
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Polymorphic Variability in the Interleukin (IL)-1b Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1b Production by Ouma, Collins, Davenport, Gregory C, Awandare, Gordon A, Keller, Christopher C, Were, Tom, Otieno, Michael F, Vulule, John M, Martinson, Jeremy, Ong'echa, John M, Ferrell, Robert E, Perkins, Douglas J

“…Interleukin (IL)-1b is a cytokine released as part of the innate immune response to Plasmodium falciparum. Because the role played by IL-1b polymorphic…”
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Association of FCgamma receptor IIA (CD32) polymorphism with malarial anemia and high-density parasitemia in infants and young children by Ouma, Collins, Keller, Christopher C, Opondo, Dorothy A, Were, Tom, Otieno, Richard O, Otieno, Michael F, Orago, Alloys S S, Ong'Echa, John M, Vulule, John M, Ferrell, Robert E, Perkins, Douglas J

“…Protective immunity against Plasmodium falciparum is partially mediated through binding of malaria-specific IgG antibodies to Fcgamma receptors. Polymorphic…”
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