Search Results - "Othumpangat, Sreekumar"

MicroRNA-221 modulates RSV replication in human bronchial epithelium by targeting NGF expression by Othumpangat, Sreekumar, Walton, Cheryl, Piedimonte, Giovanni

“…Early-life infection by respiratory syncytial virus (RSV) is associated with aberrant expression of the prototypical neurotrophin nerve growth factor (NGF) and…”
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β-Defensin-1 Regulates Influenza Virus Infection in Human Bronchial Epithelial Cells through the STAT3 Signaling Pathway by Othumpangat, Sreekumar, Noti, John D

“…Understanding the host response to influenza A virus (IAV) infection is vital for developing intervention strategies. The primary barriers for invading…”
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ICAM-1 regulates the survival of influenza virus in lung epithelial cells during the early stages of infection by Othumpangat, Sreekumar, Noti, John D, McMillen, Cynthia M, Beezhold, Donald H

“…Abstract Intercellular cell adhesion molecule-1 (ICAM-1) is an inducible cell surface glycoprotein that is expressed on many cell types. Influenza virus…”
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Viable influenza A virus in airborne particles expelled during coughs versus exhalations by Lindsley, William G., Blachere, Francoise M., Beezhold, Donald H., Thewlis, Robert E., Noorbakhsh, Bahar, Othumpangat, Sreekumar, Goldsmith, William T., McMillen, Cynthia M., Andrew, Michael E., Burrell, Carmen N., Noti, John D.

“…Background To prepare for a possible influenza pandemic, a better understanding of the potential for the airborne transmission of influenza from person to…”
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Influenza Virus-Induced Novel miRNAs Regulate the STAT Pathway by Othumpangat, Sreekumar, Beezhold, Donald H, Umbright, Christina M, Noti, John D

“…MicroRNAs (miRNAs) are essential regulators of gene expression in humans and can control pathogenesis and host-virus interactions. Notably, the role of…”
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Topical exposure to triclosan inhibits Th1 immune responses and reduces T cells responding to influenza infection in mice by Shane, Hillary L, Othumpangat, Sreekumar, Marshall, Nikki B, Blachere, Francoise, Lukomska, Ewa, Weatherly, Lisa M, Baur, Rachel, Noti, John D, Anderson, Stacey E

“…Healthcare workers concurrently may be at a higher risk of developing respiratory infections and allergic disease, such as asthma, than the general public…”
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Respiratory syncytial virus infection in human bone marrow stromal cells by Rezaee, Fariba, Gibson, Laura F, Piktel, Debbie, Othumpangat, Sreekumar, Piedimonte, Giovanni

“…Respiratory syncytial virus (RSV) is the most common respiratory pathogen in infants and young children. The pathophysiology of this infection in the…”
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Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival by Othumpangat, Sreekumar, Bryan, Nicole B, Beezhold, Donald H, Noti, John D

“…Influenza A virus (IAV) infection remains a significant cause of morbidity and mortality worldwide. One key transcription factor that is activated upon IAV…”
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Inhibition of influenza A virus matrix and nonstructural gene expression using RNA interference by McMillen, Cynthia M, Beezhold, Donald H, Blachere, Francoise M, Othumpangat, Sreekumar, Kashon, Michael L, Noti, John D

“…Abstract Influenza antiviral drugs that use protein inhibitors can lose their efficacy as resistant strains emerge. As an alternative strategy, we investigated…”
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NGF is an essential survival factor for bronchial epithelial cells during respiratory syncytial virus infection by Othumpangat, Sreekumar, Gibson, Laura F, Samsell, Lennie, Piedimonte, Giovanni

“…Overall expression of neurotrophins in the respiratory tract is upregulated in infants infected by the respiratory syncytial virus (RSV), but it is unclear…”
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Differential Expression of Serum Exosome microRNAs and Cytokines in Influenza A and B Patients Collected in the 2016 and 2017 Influenza Seasons by Othumpangat, Sreekumar, Lindsley, William G, Beezhold, Donald H, Kashon, Michael L, Burrell, Carmen N, Mubareka, Samira, Noti, John D

“…MicroRNAs (miRNAs) have remarkable stability and are key regulators of mRNA transcripts for several essential proteins required for the survival of cells and…”
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Eukaryotic Translation Initiation Factor 4E Is a Cellular Target for Toxicity and Death Due to Exposure to Cadmium Chloride by Othumpangat, Sreekumar, Kashon, Michael, Joseph, Pius

“…Whether translation initiation factor 4E (eIF4E), the mRNA cap binding and rate-limiting factor required for translation, is a target for cytotoxicity and cell…”
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β-defensin-1 regulates influenza virus infection in human bronchial epithelial cells through the STAT3 signaling Pathway by Othumpangat, Sreekumar, Noti, John D

“…To develop intervention strategies it is necessary to understand the host response to influenza A virus (IAV) infection. The primary barriers for invading…”
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Data-based analysis, modelling and forecasting of the COVID-19 outbreak by Anastassopoulou, Cleo, Russo, Lucia, Tsakris, Athanasios, Siettos, Constantinos

“…Since the first suspected case of coronavirus disease-2019 (COVID-19) on December 1st, 2019, in Wuhan, Hubei Province, China, a total of 40,235 confirmed cases…”
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Nerve growth factor modulates human rhinovirus infection in airway epithelial cells by controlling ICAM-1 expression by Othumpangat, Sreekumar, Regier, Michael, Piedimonte, Giovanni

“…Human rhinoviruses (HRV) are the most common agent of upper respiratory infections and an important cause of lower respiratory tract symptoms. Our previous…”
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Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome c oxidase VIc which is modulated by miRNA 4276 by Othumpangat, Sreekumar, Noti, John D, Beezhold, Donald H

“…Abstract Influenza virus infection induces several changes in host miRNA profile, host cell death and tissue damage. Cytochrome c is a regulator of the…”
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Expression of chemokines and cytokines in influenza A and B patients have a significant correlation to the levels of serum miRNAs by Othumpangat, Sreekumar, William, Lindsley G, Beezhold, Donald H, Kashon, Michael L, Burrell, Carmen N, Mubareka, Samira, Noti, John D

“…Several host cytokines display differential expression in blood plasma and serum levels during influenza virus infection. Influenza may induce a T helper 2…”
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Influenza virus infection modulates the death receptor pathway during early stages of infection in human bronchial epithelial cells by Othumpangat, Sreekumar, Beezhold, Donald H, Noti, John D

“…Host-viral interaction occurring throughout the infection process between the influenza A virus (IAV) and bronchial cells determines the success of infection…”
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Lung epithelial cells resist influenza A infection by inducing the expression of cytochrome VI C oxidase that is regulated by hsa‐miR‐4276 (1138.4) by Othumpangat, Sreekumar, Noti, John, Beezhold, Donald

“…MicroRNAs regulate at least one third of all human genes and are phylogenetically well conserved. Influenza A virus infection induces several changes in host…”
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ICAM1 regulates influenza A survival in lung epithelial cells during the early stages of infection (796.5) by Othumpangat, Sreekumar, Noti, John, Beezhold, Donald

“…Intercellular cell adhesion molecule‐1 (CD54 or ICAM‐1) is an inducible cell surface glycoprotein that is expressed at low levels on many cell types including…”
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