Search Results - "Otero González, Anselmo"
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Antimicrobial magnetic nanoparticles based-therapies for controlling infectious diseases
Published in International journal of pharmaceutics (30-01-2019)“…[Display omitted] •Induction.•Magnetic nanoparticles (MNPs) synthesis and functionalization.•Antimicrobial activity of MNPs.•Antimicrobial drug delivery by…”
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A Cerberus‐Inspired Anti‐Infective Multicomponent Gatekeeper Hydrogel against Infections with the Emerging “Superbug” Yeast Candida auris
Published in Macromolecular bioscience (01-04-2020)“…The pathogenic yeast Candida auris has received increasing attention due to its ability to cause fatal infections, its resistance toward important fungicides,…”
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Host defense peptides as immunomodulators: The other side of the coin
Published in Peptides (New York, N.Y. : 1980) (01-12-2021)“…Host defense peptides (HDPs) exhibit a broad range of antimicrobial and immunomodulatory activities. In this sense, both functions are like different sides of…”
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Aminocatalysis-Mediated on-Resin Ugi Reactions: Application in the Solid-Phase Synthesis of N‑Substituted and Tetrazolo Lipopeptides and Peptidosteroids
Published in Organic letters (05-06-2015)“…A new solid-phase protocol for the synthesis of N-substituted and tetrazolo peptides is described. The strategy relies on the combination of…”
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Cm‐p5: an antifungal hydrophilic peptide derived from the coastal mollusk Cenchritis muricatus (Gastropoda: Littorinidae)
Published in The FASEB journal (01-08-2015)“…Antimicrobial peptides form part of the first line of defense against pathogens formany organisms. Current treatments for fungal infections are limited by drug…”
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A multicomponent macrocyclization strategy to natural product-like cyclic lipopeptides: synthesis and anticancer evaluation of surfactin and mycosubtilin analogues
Published in Organic & biomolecular chemistry (03-05-2017)“…A multicomponent macrocyclization strategy towards cyclic lipopeptides is described. The approach relies on the utilization of the Ugi and Passerini…”
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Discovery, Optimization, and Clinical Application of Natural Antimicrobial Peptides
Published in Biomedicines (03-10-2021)“…Antimicrobial peptides (AMPs) are widespread in multicellular organisms. These structurally diverse molecules are produced as the first line of defense against…”
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Host defense peptides: An alternative as antiinfective and immunomodulatory therapeutics
Published in Biopolymers (2012)“…Host defense peptides are conserved components of innate immune response present among all classes of life. These peptides are potent, broad spectrum…”
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Design of a Helical-Stabilized, Cyclic, and Nontoxic Analogue of the Peptide Cm-p5 with Improved Antifungal Activity
Published in ACS omega (19-11-2019)“…Following the information obtained by a rational design study, a cyclic and helical-stabilized analogue of the peptide Cm-p5 was synthetized. The cyclic…”
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Functional characterization of a synthetic hydrophilic antifungal peptide derived from the marine snail Cenchritis muricatus
Published in Biochimie (01-04-2012)“…Antimicrobial peptides have been found in mollusks and other sea animals. In this report, a crude extract of the marine snail Cenchritis muricatus was…”
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Antifungal nanofibers made by controlled release of sea animal derived peptide
Published in Nanoscale (01-01-2015)“…Candida albicans is a common human-pathogenic fungal species with the ability to cause several diseases including surface infections. Despite the clear…”
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New Antibacterial Peptides from the Freshwater Mollusk Pomacea poeyana (Pilsbry, 1927)
Published in Biomolecules (Basel, Switzerland) (23-10-2020)“…Antimicrobial peptides (AMPs) are biomolecules with antimicrobial activity against a broad group of pathogens. In the past few decades, AMPs have represented…”
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LPS inmobilization on porous and non-porous supports as an approach for the isolation of anti-LPS host-defense peptides
Published in Frontiers in microbiology (17-12-2013)“…Lipopolysaccharides (LPSs) are the major molecular component of the outer membrane of Gram-negative bacteria. This molecule is recognized as a sign of…”
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Identification and Characterization of Three New Antimicrobial Peptides from the Marine Mollusk Nerita versicolor (Gmelin, 1791)
Published in International journal of molecular sciences (14-02-2023)“…Mollusks have been widely investigated for antimicrobial peptides because their humoral defense against pathogens is mainly based on these small biomolecules…”
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Antimicrobial Peptides Pom-1 and Pom-2 from Pomacea poeyana Are Active against Candida auris , C. parapsilosis and C. albicans Biofilms
Published in Pathogens (Basel) (20-04-2021)“…Recently two peptides isolated from the Cuban freshwater snail (Pilsbry, 1927) were described to have antimicrobial activity against bacterial pathogens. Here…”
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Cm-p5 Peptide Dimers Inhibit Biofilms of Candida albicans Clinical Isolates, C. parapsilosis and Fluconazole-Resistant Mutants of C. auris
Published in International journal of molecular sciences (06-06-2023)“…Antimicrobial peptides (AMPs) represent a promising class of therapeutic biomolecules that show antimicrobial activity against a broad range of microorganisms,…”
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The intrinsic antimicrobial activity of citric acid-coated manganese ferrite nanoparticles is enhanced after conjugation with the antifungal peptide Cm-p5
Published in International journal of nanomedicine (01-01-2016)“…Diseases caused by bacterial and fungal pathogens are among the major health problems in the world. Newer antimicrobial therapies based on novel molecules…”
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Structural and functional evaluation of the palindromic alanine-rich antimicrobial peptide Pa-MAP2
Published in Biochimica et biophysica acta (01-07-2016)“…Recently, several peptides have been studied regarding the defence process against pathogenic microorganisms, which are able to act against different targets,…”
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The Designed Pore-Forming Antimicrobial Peptide C14R Combines Excellent Activity against the Major Opportunistic Human Pathogen Pseudomonas aeruginosa with Low Cytotoxicity
Published in Pharmaceuticals (Basel, Switzerland) (09-01-2024)“…The diminishing portfolio of mankind's available antibiotics urges science to develop novel potent drugs. Here, we present a peptide fitting the typical…”
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Antimicrobial Peptides Pom-1 and Pom-2 from Pomacea poeyana Are Active against Candidaauris, C. parapsilosis and C. albicans Biofilms
Published in Pathogens (Basel) (20-04-2021)“…Recently two peptides isolated from the Cuban freshwater snail Pomacea poeyana (Pilsbry, 1927) were described to have antimicrobial activity against bacterial…”
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