Search Results - "Oteiza, P I"

Zinc and the ERK Kinases in the Developing Brain by Nuttall, J. R., Oteiza, P. I.

“…This article reviews evidence in support of the hypothesis that impaired activation of the extracellular signal-regulated kinases (ERK1/2) contributes to the…”
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Flavonoids and the gastrointestinal tract: Local and systemic effects by Oteiza, P.I., Fraga, C.G., Mills, D.A., Taft, D.H.

“…The gastrointestinal (GI) tract plays a central role in the absorption, distribution, metabolism, and excretion of flavonoids, which ultimately define the…”
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Lead intoxication: antioxidant defenses and oxidative damage in rat brain by Adonaylo, V.N, Oteiza, P.I

“…Oxidative damage associated with the presence of lead (Pb) in the brain has been proposed as one possible mechanism involved in Pb toxicity. To investigate…”
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The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects by Erlejman, A G, Verstraeten, S V, Fraga, C G, Oteiza, P I

“…Twenty six phenolic substances including representatives of the families, flavanones, flavanols and procyanidins, flavonols, isoflavones, phenolic acids and…”
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Nutritional marginal zinc deficiency disrupts placental 11β-hydroxysteroid dehydrogenase type 2 modulation by Huang, Y L, Supasai, S, Kucera, H, Gaikwad, N W, Adamo, A M, Mathieu, P, Oteiza, P I

“…This paper investigated if marginal zinc nutrition during gestation could affect fetal exposure to glucocorticoids as a consequence of a deregulation of…”
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Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes by Oteiza, P I, Olin, K L, Fraga, C G, Keen, C L

“…To investigate the effects of zinc deficiency on oxidative damage to testes proteins, lipids and DNA, weanling male rats were allowed free access to low (0.5…”
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Zinc and the modulation of Nrf2 in human neuroblastoma cells by Kaufman, Z., Salvador, G.A., Liu, X., Oteiza, P.I.

“…Zinc plays a key role in the modulation of neuronal redox homeostasis. A decreased zinc availability is associated with neuronal NADPH oxidase and nitric oxide…”
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Pb2+ promotes lipid oxidation and alterations in membrane physical properties by ADONAYLO, V. N, OTEIZA, P. I

“…Experimental evidence suggests that cellular damage mediated by oxidants could be involved in the pathology associated with lead (Pb) toxicity. We investigated…”
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A mechanism for the stimulatory effect of aluminum on iron-induced lipid peroxidation by Oteiza, P I

“…This study was conducted to determine whether Al, a metal without redox capacity in biological systems, can stimulate Fe(2+)-supported lipid peroxidation…”
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Cadmium-induced testes oxidative damage in rats can be influenced by dietary zinc intake by Oteiza, Patricia I., Adonaylo, Viviana N., Keen, Carl L.

“…We tested the hypothesis that zinc deficient animals would be characterized by an increased sensitivity to cadmium-induced oxidative damage to the testes…”
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Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms by Supasai, S., Aimo, L., Adamo, A.M., Mackenzie, G.G., Oteiza, P.I.

“…Zinc deficiency affects the development of the central nervous system (CNS) through mechanisms only partially understood. We previously showed that zinc…”
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The antioxidant properties of zinc: interactions with iron and antioxidants by Zago, M.Paola, Oteiza, Patricia I

“…Potential mechanisms underlying zinc’s capacity to protect membranes from lipid oxidation were examined in liposomes. Using lipid oxidation initiators with…”
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Aluminum enhances melanin-induced lipid peroxidation by MEGLIO, L, OTEIZA, P. I

“…The present study was conducted to characterize the possible interaction of Al3+ and Fe2+ with synthetic melanin in the potentiation of lipid peroxidation in…”
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5-aminolevulinic acid induces lipid peroxidation in cardiolipin-rich liposomes by Oteiza, P I, Bechara, E J

“…5-Aminolevulinic acid (ALA), a heme precursor accumulated in lead poisoning and acute intermittent porphyria, is known to undergo metal-catalyzed aerobic…”
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Aluminum has both oxidant and antioxidant effects in mouse brain membranes by Oteiza, P I, Fraga, C G, Keen, C L

“…The in vitro effects of aluminum (Al) on lipid peroxidation were studied in mouse brain homogenates and purified brain subcellular fractions. In brain…”
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Zinc deficiency induces oxidative stress and AP-1 activation in 3T3 cells by Oteiza, Patricia I, Clegg, Michael S, Zago, M.Paola, Keen, Carl L

“…It has been postulated that one mechanism underlying zinc deficiency–induced tissue alterations is excessive cellular oxidative damage. In the present study we…”
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Aluminum accumulation and neurotoxicity in Swiss-Webster mice after long-term dietary exposure to aluminum and citrate by Oteiza, P I, Keen, C L, Han, B, Golub, M S

“…The present study was performed to determine aluminum uptake, retention, and neurotoxic effects in the presence of dietary citrate. Six-week-old female…”
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Evaluation of antioxidants, protein, and lipid oxidation products in blood from sporadic amiotrophic lateral sclerosis patients by OTEIZA, P. I, UCHITEL, O. D, CARRASQUEDO, F, DUBROVSKI, A. L, ROMA, J. C, FRAGA, C. G

“…Issue Title: Dedicated to Dr. Eduardo Soto Several parameters indicators of oxidative stress were evaluated in blood from individuals with the sporadic form of…”
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The oxidant defense system in human neuroblastoma IMR-32 cells predifferentiation and postdifferentiation to neuronal phenotypes by ERLEJMAN, Alejandra G, OTEIZA, Patricia I

“…Differentiated neurons were investigated for their susceptibility to oxidative damage based on variations in the oxidant defense system occurring during…”
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Zinc in the prevention of Fe2+-initiated lipid and protein oxidation by Zago, M P, Verstraeten, S V, Oteiza, P I

“…In the present study we characterized the capacity of zinc to protect lipids and proteins from Fe2+-initiated oxidative damage. The effects of zinc on lipid…”
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