Search Results - "Otani, Ryohei"

Selection bias due to delayed comprehensive genomic profiling in Japan by Tamura, Taichi, Ikegami, Masachika, Kanemasa, Yusuke, Yomota, Makiko, Furusawa, Akiko, Otani, Ryohei, Saita, Chiaki, Yonese, Ichiro, Onishi, Tomoko, Kobayashi, Hiroshi, Akiyama, Toru, Shimoyama, Tatsu, Aruga, Tomoyuki, Yamaguchi, Tatsuro

“…Patients with advanced cancer undergo comprehensive genomic profiling in Japan only after treatment options have been exhausted. Patients with a very poor…”
Get full text

Selective Intracellular Delivery of Ganglioside GM3-Binding Peptide through Caveolae/Raft-Mediated Endocytosis by Matsubara, Teruhiko, Otani, Ryohei, Yamashita, Miki, Maeno, Haruka, Nodono, Hanae, Sato, Toshinori

“…Glycosphingolipids are major components of the membrane raft, and several kinds of viruses and bacterial toxins are known to bind to glycosphingolipids in the…”
Get full text

IDH‐mutated astrocytomas with 19q‐loss constitute a subgroup that confers better prognosis by Otani, Ryohei, Uzuka, Takeo, Higuchi, Fumi, Matsuda, Hadzki, Nomura, Masashi, Tanaka, Shota, Mukasa, Akitake, Ichimura, Koichi, Kim, Phyo, Ueki, Keisuke

“…IDH‐mutant gliomas are classified into astrocytic or oligodendroglial tumors by 1p/19q status in the WHO 2016 classification, with the latter presenting with…”
Get full text

Gene expression profiling of 19q-loss astrocytomas suggest a specific pattern associated with the better prognosis by Otani, Ryohei, Mukasa, Akitake, Uzuka, Takeo, Higuchi, Fumi, Matsuda, Hadzki, Nomura, Masashi, Tanaka, Shota, Kim, Phyo, Ueki, Keisuke

“…Purpose We previously reported that there was a subgroup of IDH -mutated astrocytomas harboring only 19q-loss showing oligodendroglioma-like morphology and…”
Get full text

Classification of adult diffuse gliomas by molecular markers-a short review with historical footnote by Otani, Ryohei, Uzuka, Takeo, Ueki, Keisuke

“…Classification of gliomas, first established by Cushing and Bailey in early 20th century, has been based on histological features that were associated with…”
Get full text

Distinct molecular profile of diffuse cerebellar gliomas by Nomura, Masashi, Mukasa, Akitake, Nagae, Genta, Yamamoto, Shogo, Tatsuno, Kenji, Ueda, Hiroki, Fukuda, Shiro, Umeda, Takayoshi, Suzuki, Tomonari, Otani, Ryohei, Kobayashi, Keiichi, Maruyama, Takashi, Tanaka, Shota, Takayanagi, Shunsaku, Nejo, Takahide, Takahashi, Satoshi, Ichimura, Koichi, Nakamura, Taishi, Muragaki, Yoshihiro, Narita, Yoshitaka, Nagane, Motoo, Ueki, Keisuke, Nishikawa, Ryo, Shibahara, Junji, Aburatani, Hiroyuki, Saito, Nobuhito

“…Recent studies have demonstrated that tumor-driving alterations are often different among gliomas that originated from different brain regions and have…”
Get full text

DNA demethylation is associated with malignant progression of lower-grade gliomas by Nomura, Masashi, Saito, Kuniaki, Aihara, Koki, Nagae, Genta, Yamamoto, Shogo, Tatsuno, Kenji, Ueda, Hiroki, Fukuda, Shiro, Umeda, Takayoshi, Tanaka, Shota, Takayanagi, Shunsaku, Otani, Ryohei, Nejo, Takahide, Hana, Taijun, Takahashi, Satoshi, Kitagawa, Yosuke, Omata, Mayu, Higuchi, Fumi, Nakamura, Taishi, Muragaki, Yoshihiro, Narita, Yoshitaka, Nagane, Motoo, Nishikawa, Ryo, Ueki, Keisuke, Saito, Nobuhito, Aburatani, Hiroyuki, Mukasa, Akitake

“…To elucidate the mechanisms of malignant progression of lower-grade glioma, molecular profiling using methylation array, whole-exome sequencing, and RNA…”
Get full text

Brain invasion by chronic lymphocytic leukemia by Otani, Ryohei, Uzuka, Takeo, Matsuda, Hadzki, Higuchi, Fumi, Kim, Phyo, Ueki, Keisuke

“…Brain invasion by chronic lymphocytic leukemia (CLL) is very rare, and only a handful of cases have been reported. We here report a case of 61‐year‐old woman…”
Get full text

Clinical outcomes of brain metastases from hepatocellular carcinoma: a multicenter retrospective study and a literature review by Okuda, Takeshi, Hayashi, Nakamasa, Takahashi, Masamichi, Uzuka, Takeo, Okita, Yoshiko, Otani, Ryohei, Fujinaka, Toshiyuki, Fujita, Mitsugu, Kato, Amami, Narita, Yoshitaka, Nakasu, Yoko

“…Introduction The introduction of systemic chemotherapy for advanced hepatocellular carcinoma in recent years has led to the prediction that cases of brain…”
Get full text

Intravascular Lymphoma with an Acute Course of Cerebellar Hemorrhage: A Case Report by UZUKA, Takeo, HIGUCHI, Fumi, MATSUDA, Hadzuki, OTANI, Ryohei, KIM, Phyo, UEKI, Keisuke

“…Intravascular lymphoma (IVL) has been characterized in many case reports by multiple white matter lesions reflecting ischemic changes. In contrast, there are…”
Get full text

Pial Arteriovenous Fistula Caused by Trauma: A Case Report by NOMURA, Seiji, ISHIKAWA, Osamu, TANAKA, Kentaro, OTANI, Ryohei, MIURA, Keisuke, MAEDA, Keiichiro

“…We report an extremely rare case of pial arteriovenous fistula (AVF) caused by trauma. A 61-year-old man suffered from brain contusion by a traffic accident…”
Get full text

Publisher Correction: DNA demethylation is associated with malignant progression of lower-grade gliomas by Nomura, Masashi, Saito, Kuniaki, Aihara, Koki, Nagae, Genta, Yamamoto, Shogo, Tatsuno, Kenji, Ueda, Hiroki, Fukuda, Shiro, Umeda, Takayoshi, Tanaka, Shota, Takayanagi, Shunsaku, Otani, Ryohei, Nejo, Takahide, Hana, Taijun, Takahashi, Satoshi, Kitagawa, Yosuke, Omata, Mayu, Higuchi, Fumi, Nakamura, Taishi, Muragaki, Yoshihiro, Narita, Yoshitaka, Nagane, Motoo, Nishikawa, Ryo, Ueki, Keisuke, Saito, Nobuhito, Aburatani, Hiroyuki, Mukasa, Akitake

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
Get full text

Damage to the right dorsal anterior cingulate cortex induces panic disorder by Shinoura, Nobusada, Yamada, Ryozi, Tabei, Yusuke, Otani, Ryohei, Itoi, Chihiro, Saito, Seiko, Midorikawa, Akira

“…Abstract Brain imaging studies suggest that panic disorder (PD) is mediated by several brain regions, including the anterior cingulate cortex (ACC). In the…”
Get full text

Rapid Growth Hormone Measurement During Transsphenoidal Surgery: Analysis of 252 Acromegalic Patients by OTANI, Ryohei, FUKUHARA, Noriaki, OCHI, Takashi, OYAMA, Kenichi, YAMADA, Shozo

“…The usefulness of rapid growth hormone (GH) measurement was retrospectively evaluated as an indicator of total tumor removal during surgery and compared with…”
Get full text

Update Knowledge for Brain Tumors (4) Oligodendroglial Tumors by Uzuka, Takeo, Otani, Ryohei, Ueki, Keisuke

Get more information

Mitochondrial respiratory complex I can be inhibited via bypassing the ubiquinone‐accessing tunnel by Otani, Ryohei, Masuya, Takahiro, Miyoshi, Hideto, Murai, Masatoshi

“…Mitochondrial NADH–ubiquinone oxidoreductase (complex I) couples electron transfer from NADH to ubiquinone with proton translocation in its membrane part…”
Get full text

Characterization of the ubiquinone reaction cavity in mitochondrial respiratory complex I using artificial ligands by Masuya, Takahiro, Otani, Ryohei, Ikunishi, Ryo, Shinzawa-Itoh, Kyoko, Shiba, Tomoo, Murai, Masatoshi, Miyoshi, Hideto

Get full text

Genetic Characteristics of Mismatch Repair-deficient Glioblastoma by KAWAGUCHI, Kei, OTANI, Ryohei, KIKUCHI, Miyu, KUSHIHARA, Yoshihiro, FUNATA, Nobuaki, YAMADA, Ryoji, SHINOURA, Nobusada

“…Mismatch repair (MMR) gene deficiency is rarely observed in gliomas, a constitutional defect is associated with tumorigenesis in Lynch syndrome, and an…”
Get full text

Brachyury gene copy number gain and activation of the PI3K/Akt pathway: association with upregulation of oncogenic Brachyury expression in skull base chordoma by Otani, Ryohei, Mukasa, Akitake, Shin, Masahiro, Omata, Mayu, Takayanagi, Shunsaku, Tanaka, Shota, Ueki, Keisuke, Saito, Nobuhito

“…OBJECTIVE Chordoma is a slow-growing but clinically malignant tumor, and the prognosis remains poor in many cases. There is a strong impetus to develop more…”
Get full text

CHD5 gene variant predicts leptomeningeal metastasis after surgical resection of brain metastases of breast cancer by Otani, Ryohei, Sadato, Daichi, Yamada, Ryoji, Yajima, Hirohisa, Kawamura, Shinji, Shimizu, Sakura, Tanaka, Shota, Takayanagi, Shunsaku, Takami, Hirokazu, Yamaguchi, Tatsuro

“…Purpose Leptomeningeal metastasis (LM) is a complication of surgery for brain metastasis and is a risk factor of poor prognosis. The risk of LM is particularly…”
Get full text