Search Results - "Otani, Hiroto"

Structural Basis for Substrate Recognition and Hydrolysis by Mouse Carnosinase CN2 by Unno, Hideaki, Yamashita, Tetsuo, Ujita, Sayuri, Okumura, Nobuaki, Otani, Hiroto, Okumura, Akiko, Nagai, Katsuya, Kusunoki, Masami

“…l-Carnosine is a bioactive dipeptide (β-alanyl-l-histidine) present in mammalian tissues, including the central nervous system, and has potential…”
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Lineage-specific positive selection at the merozoite surface protein 1 (msp1) locus of Plasmodium vivax and related simian malaria parasites by Sawai, Hiromi, Otani, Hiroto, Arisue, Nobuko, Palacpac, Nirianne, de Oliveira Martins, Leonardo, Pathirana, Sisira, Handunnetti, Shiroma, Kawai, Satoru, Kishino, Hirohisa, Horii, Toshihiro, Tanabe, Kazuyuki

“…The 200 kDa merozoite surface protein 1 (MSP-1) of malaria parasites, a strong vaccine candidate, plays a key role during erythrocyte invasion and is a target…”
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Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves by Nagai, Katsuya, Niijima, Akira, Yamano, Toshihiko, Otani, Hiroto, Okumra, Nobuaki, Tsuruoka, Nobuo, Nakai, Masaaki, Kiso, Yoshinobu

“…Mammalian muscles synthesize L-carnosine, but its roles were unknown. Previously, we found in rats that the administration of a certain amount of L-carnosine…”
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Effects of central injection of l-carnosine on sympathetic nerve activity innervating brown adipose tissue and body temperature in rats by Tanida, Mamoru, Gotoh, Hitoshi, Taniguchi, Hiroyuki, Otani, Hiroto, Shen, Jiao, Nakamura, Takuo, Tsuruoka, Nobuo, Kiso, Yoshinobu, Okumura, Nobuaki, Nagai, Katsuya

“…In the present study, using urethane-anesthetized rats, we examined the effects of intralateral cerebral ventricular (LCV) injection of various doses of…”
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Identification and Characterization of a Mouse Dipeptidase That Hydrolyzes l-Carnosine by Otani, Hiroto, Okumura, Nobuaki, Hashida-Okumura, Akiko, Nagai, Katsuya

“…l-Carnosine is a bioactive dipeptide present in mammalian tissues including the central nervous system. We have recently shown that l-carnosine is involved in…”
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1C-10 Natural selection on the merozoite surface protein 1 gene (msp1) of human malaria parasites by SAWAI Hiromi, OTANI Hiroto, TANABE Kazuyuki

“…Malaria, caused by malaria parasites the genus Plasmodium, affects 300-500 million people annually with over one million deaths. The Plasmodium merozoite…”
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Stimulation of BIT induces a circadian phase shift of locomotor activity in rats by Nakahata, Yasukazu, Okumura, Nobuaki, Otani, Hiroto, Hamada, Juri, Numakawa, Tadahiro, Sano, Shin-ichiro, Nagai, Katsuya

“…Circadian rhythms of mammals are generated by a circadian oscillation of master pacemaker genes in the suprachiasmatic nucleus of the hypothalamus (SCN), and…”
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Colocalization of a carnosine-splitting enzyme, tissue carnosinase (CN2)/cytosolic non-specific dipeptidase 2 (CNDP2), with histidine decarboxylase in the tuberomammillary nucleus of the hypothalamus by Otani, Hiroto, Okumura, Akiko, Nagai, Katsuya, Okumura, Nobuaki

“…Carnosine is a naturally occurring dipeptide (β-alanyl- l-histidine) present in mammalian tissues such as the brain and skeletal muscles. Carnosine is not only…”
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Big Bang in the Evolution of Extant Malaria Parasites by Hayakawa, Toshiyuki, Culleton, Richard, Otani, Hiroto, Horii, Toshihiro, Tanabe, Kazuyuki

“…Malaria parasites (genus Plasmodium) infect all classes of terrestrial vertebrates and display host specificity in their infections. It is therefore assumed…”
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Lineage-specific positive selection at the merozoite surface protein 1 by Sawai, Hiromi, Otani, Hiroto, Arisue, Nobuko, Palacpac, Nirianne, de Oliveira Martins, Leonardo, Pathirana, Sisira, Handunnetti, Shiroma, Kawai, Satoru, Kishino, Hirohisa, Horii, Toshihiro, Tanabe, Kazuyuki

“…The 200 kDa merozoite surface protein 1 (MSP-1) of malaria parasites, a strong vaccine candidate, plays a key role during erythrocyte invasion and is a target…”
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Effects of central injection of L-camosine on sympathetic nerve activity innervating brown adipose tissue and body temperature in rats by TANIDA, Mamoru, GOTOH, Hitoshi, TANIGUCHI, Hiroyuki, OTANI, Hiroto, JIAO SHEN, NAKAMURA, Takuo, TSURUOKA, Nobuo, KISO, Yoshinobu, OKUMURA, Nobuaki, NAGAI, Katsuya

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Crystallization and preliminary crystallographic study of carnosinase CN2 from mice by Yamashita, Tetsuo, Unno, Hideaki, Ujita, Sayuri, Otani, Hiroto, Nagai, Katsuya, Okumura, Nobuaki, Hashida-Okumura, Akiko, Kusunoki, Masami

“…Mammalian tissues contain several histidine‐containing dipeptides, of which l‐­carnosine is the best characterized and is found in various tissues including…”
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