Search Results - "Otaki, Shizuo"

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  1. 1

    Structural Comparison of Fucosylated and Nonfucosylated Fc Fragments of Human Immunoglobulin G1 by Matsumiya, Shigeki, Yamaguchi, Yoshiki, Saito, Jun-ichi, Nagano, Mayumi, Sasakawa, Hiroaki, Otaki, Shizuo, Satoh, Mitsuo, Shitara, Kenya, Kato, Koichi

    Published in Journal of molecular biology (04-05-2007)
    “…Removal of the fucose residue from the oligosaccharides attached to Asn297 of human immunoglobulin G1 (IgG1) results in a significant enhancement of…”
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    Journal Article
  2. 2

    UCS1025A and B, New Antitumor Antibiotics from the Fungus Acremonium Species by Agatsuma, Tsutomu, Akama, Tsutomu, Nara, Shinji, Matsumiya, Shigeki, Nakai, Ryuichiro, Ogawa, Harumi, Otaki, Shizuo, Ikeda, Shun-ichi, Saitoh, Yutaka, Kanda, Yutaka

    Published in Organic letters (12-12-2002)
    “…UCS1025A and B, novel pentacyclic polyketides with an unprecedented furopyrrolizidine skeleton, were isolated from the fungus Acremonium sp. KY4917. The…”
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  3. 3

    Discovery and Structure−Activity Relationships of Novel Piperidine Inhibitors of Farnesyltransferase by Nara, Shinji, Tanaka, Rieko, Eishima, Jun, Hara, Mitsunobu, Takahashi, Yuichi, Otaki, Shizuo, Foglesong, Robert J, Hughes, Philip F, Turkington, Shelley, Kanda, Yutaka

    Published in Journal of medicinal chemistry (05-06-2003)
    “…A novel piperidine series of farnesyltransferase (FTase) inhibitors is described. Systematic medicinal chemistry studies starting with the lead compound,…”
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  4. 4

    Unique binding pocket for KW-4679 in the histamine H1 receptor by NONAKA, H, OTAKI, S, OHSHIMA, E, KONO, M, KASE, H, OHTA, K, FUKUI, H, ICHIMURA, M

    Published in European journal of pharmacology (12-03-1998)
    “…The histamine H1 receptor has an aspartate (Asp) residue in transmembrane helix 3 (TM3), which is well-conserved among biogenic amine receptors. The Asp…”
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  5. 5

    Synthesis and antiallergic activity of 11-(aminoalkylidene)-6,11-dihydrodibenz[b,e]oxepin derivatives by Ohshima, Etsuo, Otaki, Shizuo, Sato, Hideyuki, Kumazawa, Toshiaki, Obase, Hiroyuki, Ishii, Akio, Ishii, Hidee, Ohmori, Kenji, Hirayama, Noriaki

    Published in Journal of medicinal chemistry (01-05-1992)
    “…A new series of 11-substituted 6,11-dihydrodibenz[b,e]oxepin-2-carboxylic acid derivatives was synthesized and demonstrated to be orally active antiallergic…”
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    Unique binding pocket for KW-4679 in the histamine H 1 receptor by Nonaka, Hiromi, Otaki, Shizuo, Ohshima, Etsuo, Kono, Motomichi, Kase, Hiroshi, Ohta, Kazumi, Fukui, Hiroyuki, Ichimura, Michio

    Published in European journal of pharmacology (12-03-1998)
    “…The histamine H 1 receptor has an aspartate (Asp) residue in transmembrane helix 3 (TM3), which is well-conserved among biogenic amine receptors. The Asp…”
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    Journal Article