Search Results - "Ostrowski, Robert"

Subependymal Giant Cell Astrocytoma: The Molecular Landscape and Treatment Advances by Pucko, Emanuela, Sulejczak, Dorota, Ostrowski, Robert P

“…Subependymal giant cell astrocytoma (SEGA) is most often found in patients with TSC (Tuberous Sclerosis Complex). Although it has been classified as a benign…”
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Harnessing oxidative stress for anti-glioma therapy by Ostrowski, Robert P., Pucko, Emanuela B.

“…Glioma cells use intermediate levels of reactive oxygen species (ROS) and reactive nitrogen species (RNS) for growth and invasion, and suppressing these…”
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Hyperbaric oxygen increases glioma cell sensitivity to antitumor treatment with a novel isothiourea derivative in vitro by Zembrzuska, Katarzyna, Ostrowski, Robert P, Matyja, Ewa

“…Glioblastoma (GBM) is the most common primary brain tumor. Tumor hypoxia is a pivotal factor responsible for the progression of this malignant glioma, and its…”
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Hyperbaric oxygen as an adjunctive therapy in treatment of malignancies, including brain tumours by Stępień, Katarzyna, Ostrowski, Robert P., Matyja, Ewa

“…Hyperbaric oxygen (HBO) therapy is widely used as an adjunctive treatment for various pathological states, predominantly related to hypoxic and/or ischaemic…”
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The insights into molecular pathways of hypoxia‐inducible factor in the brain by Ostrowski, Robert P., Zhang, John H.

“…The objectives of this present work were to review recent developments on the role of hypoxia‐inducible factor (HIF) in the survival of cells under normoxic…”
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Isoflurane on brain inflammation by Altay, Orhan, Suzuki, Hidenori, Hasegawa, Yu, Ostrowski, Robert P, Tang, Jiping, Zhang, John H

“…Abstract Brain inflammation may play an important role in the pathophysiology of early brain injury after subarachnoid hemorrhage (SAH). Our aim was to…”
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TDP-43 pathology in subacute sclerosing panencephalitis by Acewicz, Albert, Stępień, Tomasz, Grzegorczyk, Michał, Ostrowski, Robert P, Tarka, Sylwia, Felczak, Paulina, Wierzba-Bobrowicz, Teresa

“…Abstract Subacute sclerosing panencephalitis (SSPE) is a fatal, slowly progressive brain disorder caused by a mutated measles virus. Both subacute inflammatory…”
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Targeting protein kinases for anti-glioma treatment by Pucko, Emanuela, Ostrowski, Robert

“…The genetic alterations related to many kinases are responsible for the formation of glial tumours. In addition it is the cell kinases that keep the cancerous…”
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Novel small molecule protein kinase CK2 inhibitors exert potent antitumor effects on T98G and SEGA cells in vitro by Pucko, Emanuela, Ostrowski, Robert, Matyja, Ewa

“…Tumours of astroglial origin, both malignant glioblastoma (GBM) and benign subependymal giant cell astrocytoma (SEGA), pose a serious medical problem. Casein…”
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Inhibiting CK2 among Promising Therapeutic Strategies for Gliomas and Several Other Neoplasms by Pucko, Emanuela B, Ostrowski, Robert P

“…In gliomas, casein kinase 2 (CK2) plays a dominant role in cell survival and tumour invasiveness and is upregulated in many brain tumours. Among CK2…”
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Editorial: Safety and efficacy of stents and flow diverters used for embolization of acutely-ruptured intracranial aneurysms in the acute stage by Gao, Bulang, Zhang, Hongqi, Lv, Xianli, Ostrowski, Robert P., Li, Conghui

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Thermo-Mechanical Numerical Simulation of Friction Stir Rotation-Assisted Single Point Incremental Forming of Commercially Pure Titanium Sheets by Szpunar, Marcin, Trzepieciński, Tomasz, Ostrowski, Robert, Żaba, Krzysztof, Ziaja, Waldemar, Motyka, Maciej

“…Single point incremental forming (SPIF) is becoming more and more widely used in the metal industry due to its high production flexibility and the possibility…”
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Proteasome and Neuroprotective Effect of Hyperbaric Oxygen Preconditioning in Experimental Global Cerebral Ischemia in Rats by Ostrowski, Robert P, Pucko, Emanuela, Matyja, Ewa

“…We investigated the involvement of the proteasome in the mechanism of preconditioning with hyperbaric oxygen (HBO-PC). The experiments were performed on male…”
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Central Composite Design Optimisation in Single Point Incremental Forming of Truncated Cones from Commercially Pure Titanium Grade 2 Sheet Metals by Szpunar, Marcin, Ostrowski, Robert, Trzepieciński, Tomasz, Kaščák, Ľuboš

“…Single point incremental forming (SPIF) is an emerging process that is well-known to be suited for fabrication in small series production. The aim of this…”
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Potent Antitumour Effects of Novel Pentabromobenzylisothioureas Studied on Human Glial-derived Tumour Cell Lines by Pucko, Emanuela, Matyja, Ewa, Koronkiewicz, Mirosława, Ostrowski, Robert P, Kazimierczuk, Zygmunt

“…Tumours of astroglial origin are the most common primary brain malignancy characterized by infiltrative growth and resistance to standard antitumour therapy…”
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Cyclooxygenase-2 Mediates Hyperbaric Oxygen Preconditioning in the Rat Model of Transient Global Cerebral Ischemia by OUMEI CHENG, OSTROWSKI, Robert P, BIHUA WU, WENWU LIU, CHUNHUA CHEN, ZHANG, John H

“…Hyperbaric oxygen (HBO) preconditioning (PC) allows brain protection against transient global ischemia. In the present study, we hypothesize that the mechanism…”
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Effect of Lubricant Type on the Friction Behaviours and Surface Topography in Metal Forming of Ti-6Al-4V Titanium Alloy Sheets by Szpunar, Marcin, Trzepieciński, Tomasz, Żaba, Krzysztof, Ostrowski, Robert, Zwolak, Marek

“…The aim of the research described in this paper is to analyse the synergistic effect of types of synthetic oil and their density on the value of the…”
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Isoflurane Posttreatment Reduces Neonatal Hypoxic―Ischemic Brain Injury in Rats by the Sphingosine-1-Phosphate/Phosphatidylinositol- 3-Kinase/Akt Pathway by YILIN ZHOU, LEKIC, Tim, FATHALI, Nancy, OSTROWSKI, Robert P, MARTIN, Robert D, JIPING TANG, ZHANG, John H

“…Isoflurane, administered before or during cerebral ischemia, has been shown to exhibit neuroprotection in animal models of ischemic stroke. However, the…”
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Molecular mechanisms of early brain injury after subarachnoid hemorrhage by Ostrowski, Robert P., Colohan, Austin R., Zhang, John H.

“…Objectives: Increasing body of experimental and clinical data indicates that early brain injury after initial bleeding largely contributes to unfavorable…”
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Remote Limb Ischemic Postconditioning Protects Against Neonatal Hypoxic-Ischemic Brain Injury in Rat Pups by the Opioid Receptor/Akt Pathway by YILIN ZHOU, FATHALI, Nancy, LEKIC, Tim, OSTROWSKI, Robert P, CHUNHUA CHEN, MARTIN, Robert D, JIPING TANG, ZHANG, John H

“…Remote ischemic postconditoning, a phenomenon in which brief ischemic stimuli of 1 organ protect another organ against an ischemic insult, has been…”
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