Search Results - "Ostrowski, Matthew P."
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Ruminococcus torques is a keystone degrader of intestinal mucin glycoprotein, releasing oligosaccharides used by Bacteroides thetaiotaomicron
Published in mBio (14-08-2024)“…Symbiotic interactions between humans and our communities of resident gut microbes (microbiota) play many roles in health and disease. Some gut bacteria…”
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Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases
Published in Journal of antibiotics (01-07-2016)“…Ketoreductases (KRs) are the most widespread tailoring domains found in individual modules of assembly line polyketide synthases (PKSs), and are responsible…”
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Glycan processing in gut microbiomes
Published in Current opinion in microbiology (01-06-2022)“…[Display omitted] •Gut microbiomes and their enzymes enable processing of glycans consumed or secreted by the host.•Common mechanisms of glycan utilization are…”
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Protein-Protein Interactions, Not Substrate Recognition, Dominate the Turnover of Chimeric Assembly Line Polyketide Synthases
Published in The Journal of biological chemistry (29-07-2016)“…The potential for recombining intact polyketide synthase (PKS) modules has been extensively explored. Both enzyme-substrate and protein-protein interactions…”
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Mechanistic insights into consumption of the food additive xanthan gum by the human gut microbiota
Published in Nature microbiology (01-04-2022)“…Processed foods often include food additives such as xanthan gum, a complex polysaccharide with unique rheological properties, that has established widespread…”
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Widespread consumption of the common food additive xanthan gum by the human gut microbiota
Published in Nature microbiology (01-04-2022)“…The diets of industrialized countries reflect the increasing use of processed foods, often with the inclusion of novel food additives. Xanthan gum is a complex…”
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