Search Results - "Ostrow, L."

PML-IRIS in patients with HIV infection : Clinical manifestations and treatment with steroids by TAN, K, RODA, R, OSTROW, L, MCARTHUR, J, NATH, A

“…Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection that develops in immunosuppressed patients with HIV infection. Paradoxically,…”
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Global alterations to the choroid plexus blood-CSF barrier in amyotrophic lateral sclerosis by Saul, J, Hutchins, E, Reiman, R, Saul, M, Ostrow, L. W, Harris, B. T, Van Keuren-Jensen, K, Bowser, R, Bakkar, N

“…Abstract The choroid plexus (CP) is a highly vascularized structure located in the ventricles that forms the blood-CSF barrier (BCSFB) and separates the blood…”
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Cancer evolution is associated with pervasive positive selection on globally expressed genes by Ostrow, Sheli L, Barshir, Ruth, DeGregori, James, Yeger-Lotem, Esti, Hershberg, Ruth

“…Cancer is an evolutionary process in which cells acquire new transformative, proliferative and metastatic capabilities. A full understanding of cancer requires…”
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The varicella zoster virus vasculopathies : Clinical, CSF, imaging, and virologic features by NAGEL, M. A, COHRS, R. J, GREENBERG, B, RUSSMAN, A. N, KATZAN, I, GARDNER, C. J, HÄUSLER, M, NAU, R, SARAYA, T, WADA, H, GOTO, H, DE MARTINO, M, MAHALINGAM, R, UENO, M, BROWN, W. D, TERBORG, C, GILDEN, D. H, WELLISH, M. C, FORGHANI, B, SCHILLER, A, SAFDIEH, J. E, KAMENKOVICH, E, OSTROW, L. W, LEVY, M

“…Varicella zoster virus (VZV) vasculopathy produces stroke secondary to viral infection of cerebral arteries. Not all patients have rash before cerebral…”
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An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA by BEGUM, Shahnaz, BRAIT, Mariana, SIDRANSKY, David, DASGUPTA, Santanu, OSTROW, Kimberly L, ZAHURAK, Marianna, CARVALHO, André L, CALIFANO, Joseph A, GOODMAN, Steven N, WESTRA, William H, MOHAMMAD OBAIDUL HOQUE

“…We investigated the feasibility of detecting aberrant DNA methylation of some novel and known genes in the serum of lung cancer patients. To determine the…”
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Coordinated activation of candidate proto-oncogenes and cancer testes antigens via promoter demethylation in head and neck cancer and lung cancer by Smith, Ian M, Glazer, Chad A, Mithani, Suhail K, Ochs, Michael F, Sun, Wenyue, Bhan, Sheetal, Vostrov, Alexander, Abdullaev, Ziedulla, Lobanenkov, Victor, Gray, Andrew, Liu, Chunyan, Chang, Steven S, Ostrow, Kimberly L, Westra, William H, Begum, Shahnaz, Dhara, Mousumi, Califano, Joseph

“…Epigenetic alterations have been implicated in the pathogenesis of solid tumors, however, proto-oncogenes activated by promoter demethylation have been…”
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KIF1A and EDNRB are differentially methylated in primary HNSCC and salivary rinses by Demokan, Semra, Chang, Xiaofei, Chuang, Alice, Mydlarz, Wojciech K., Kaur, Jatinder, Huang, Peng, Khan, Zubair, Khan, Tanbir, Ostrow, Kimberly L., Brait, Mariana, Hoque, Mohammad O., Liegeois, Nanette J., Sidransky, David, Koch, Wayne, Califano, Joseph A.

“…Silencing of tumor suppressor genes plays a vital role in head and neck carcinogenesis. In this study, we aimed to evaluate to the utility of aberrant promoter…”
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Correlation between BRAF mutation and promoter methylation of TIMP3, RARβ2 and RASSF1A in thyroid cancer by Brait, Mariana, Loyo, Myriam, Rosenbaum, Eli, Ostrow, Kimberly L., Markova, Alina, Papagerakis, Silvana, Zahurak, Marianna, Goodman, Steven M., Zeiger, Martha, Sidransky, David, Umbricht, Christopher B., Hoque, Mohammad O.

“…Our aim was to comprehensively analyze promoter hypermethylation of a panel of novel and known methylation markers for thyroid neoplasms and to establish their…”
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A survey of methylated candidate tumor suppressor genes in nasopharyngeal carcinoma by Loyo, Myriam, Brait, Mariana, Kim, Myoung S., Ostrow, Kimberly L., Jie, Chunfa C., Chuang, Alice Y., Califano, Joseph A., Liégeois, Nanette J., Begum, Shahnaz, Westra, William H., Hoque, Mohammad O., Tao, Qian, Sidransky, David

“…Nasopharyngeal carcinoma (NPC) is a rare malignancy with unique genetic, viral and environmental characteristic that distinguishes it from other head and neck…”
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Relation of Contraceptive and Reproductive History to Ovarian Cancer Risk in Carriers and Noncarriers of BRCA1 Gene Mutations by McGuire, V., Felberg, A., Mills, M., Ostrow, K. L., DiCioccio, R., John, E. M., West, D. W., Whittemore, A. S.

“…In the general population, ovarian cancer risk is inversely associated with oral contraceptive use, tubal ligation, and childbearing. Among carriers of BRCA1…”
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Prevalence of BRCA1 Mutation Carriers among U.S. Non-Hispanic Whites by Whittemore, Alice S, Gong, Gail, John, Esther M, McGuire, Valerie, Li, Frederick P, Ostrow, Kimberly L, Dicioccio, Richard, Felberg, Anna, West, Dee W

“…Data from several countries indicate that 1% to 2% of Ashkenazi Jews carry a pathogenic ancestral mutation of the tumor suppressor gene BRCA1 . However, the…”
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Hickam's dictum and the rare convergence of antisynthetase syndrome and hemoglobin SC disease by Wilkinson, S T, Grunwald, M R, Paik, J J, Ostrow, L W, Gelber, A C

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Immunohistochemistry of affected tissue may guide cGVHD treatment decisions by Williams, K M, Ostrow, L W, Loeb, D M, Chung, T, Cohn, R D, Corse, A M, Mammen, A L, Chen, A R

“…Chronic graft-vs-host disease (cGVHD) myositis is a rare complication of hematopoietic SCT, for which the pathogenesis and optimal therapy are unclear. We…”
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ssDNA-Binding Protein 2 Is Frequently Hypermethylated and Suppresses Cell Growth in Human Prostate Cancer by LIU, Jun-Wei, NAGPAL, Jatin K, CHU SO MOON, CALIFANO, Joseph A, TRINK, Barry, SIDRANSKY, David, WENYUE SUN, LEE, Juna, MYOUNG SOOK KIM, OSTROW, Kimberly L, SHAOYU ZHOU, JERONIMO, Carmen, HENRIQUE, Rui, VAN CRIEKINGE, Wim

“…Purpose: Prostate cancer is a major cause of cancer death among men and the development of new biomarkers is important to augment current detection approaches…”
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Breast and Ovarian Cancer in Relatives of Cancer Patients, with and without BRCA Mutations by LEE, Jennifer S, JOHN, Esther M, MCGUIRE, Valerie, FELBERG, Anna, OSTROW, Kimberly L, DICIOCCIO, Richard A, LI, Frederick P, MIRON, Alexander, WEST, Dee W, WHITTEMORE, Alice S

“…Background: First-degree relatives of patients with breast or ovarian cancer have increased risks for these cancers. Little is known about how their risks vary…”
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Informatics Solutions for Driving an Effective and Efficient Radiology Practice by Doshi, Ankur M, Moore, William H, Kim, Danny C, Rosenkrantz, Andrew B, Fefferman, Nancy R, Ostrow, Dana L, Recht, Michael P

“…Radiologists are facing increasing workplace pressures that can lead to decreased job satisfaction and burnout. The increasing complexity and volumes of cases…”
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P.174 TRIM32 related muscular dystrophy mimicking inflammatory myopathy: Clinical and histopathological features in two siblings by Orbach, R., Ostrow, L., Roda, R.

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The Somatic Nature of Cancer Allows It to Affect Highly Constrained Genes by Ostrow, Sheli L, Hershberg, Ruth

“…Cancer is special among genetic disorders in two major ways: first, cancer is a disease of the most basic of cellular functions, such as cell proliferation,…”
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Variation in KRAS driver substitution distributions between tumor types is determined by both mutation and natural selection by Ostrow, Sheli L., Simon, Einav, Prinz, Elad, Bick, Tova, Shentzer, Talia, Nagawkar, Sima S., Sabo, Edmond, Ben-Izhak, Ofer, Hershberg, Ruth, Hershkovitz, Dov

“…Different tumor types vary greatly in their distribution of driver substitutions. Here, we analyzed how mutation and natural selection contribute to…”
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Mechanosensation and endothelin in astrocytes—hypothetical roles in CNS pathophysiology by Ostrow, Lyle W., Sachs, Frederick

“…Endothelin (ET) is a potent autocrine mitogen produced by reactive and neoplastic astrocytes. ET has been implicated in the induction of astrocyte…”
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