Search Results - "Ostroff, Gary R."

Yeast Particles for Encapsulation of Terpenes and Essential Oils by Soto, Ernesto R, Rus, Florentina, Mirza, Zeynep, Ostroff, Gary R

“…Terpenes and essential oils are materials of great commercial use due to their broad spectra of antibacterial, antifungal, membrane permeation enhancement and…”
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Spectrum and mechanisms of inflammasome activation by chitosan by Bueter, Chelsea L, Lee, Chrono K, Wang, Jennifer P, Ostroff, Gary R, Specht, Charles A, Levitz, Stuart M

“…Chitosan, the deacetylated derivative of chitin, can be found in the cell wall of some fungi and is used in translational applications. We have shown that…”
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Characterization of Multilayered Nanoparticles Encapsulated in Yeast Cell Wall Particles for DNA Delivery by Soto, Ernesto R, Ostroff, Gary R

“…Nonviral gene delivery technologies have been developed using layer-by-layer self-assembly of nanomaterials held together by electrostatic interactions in…”
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Yeast Particles Hyper-Loaded with Terpenes for Biocide Applications by Soto, Ernesto R, Rus, Florentina, Ostroff, Gary R

“…Yeast particles (YPs) are 3−5 µm hollow and porous microspheres, a byproduct of some food grade yeast (Saccharomyces cerevisiae) extract manufacturing…”
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Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens by Hester, Maureen M., Lee, Chrono K., Abraham, Ambily, Khoshkenar, Payam, Ostroff, Gary R., Levitz, Stuart M., Specht, Charles A.

“…•Cryptococcal protein antigens were recombinantly expressed in E. coli.•Two mouse strains were vaccinated with recombinant protein-filled glucan…”
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Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung by Alexander, Matthew P., Fiering, Steven N., Ostroff, Gary R., Cramer, Robert A., Mullins, David W.

“…β-Glucan is a naturally occurring glucose polysaccharide with immunostimulatory activity in both infection and malignancy. β-Glucan’s antitumor effects have…”
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Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes by Mirza, Zeynep, Soto, Ernesto R, Hu, Yan, Nguyen, Thanh-Thanh, Koch, David, Aroian, Raffi V, Ostroff, Gary R

“…Soil-transmitted nematodes (STN) infect 1-2 billion of the poorest people worldwide. Only benzimidazoles are currently used in mass drug administration, with…”
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Characterization and Optimization of the Glucan Particle-Based Vaccine Platform by Huang, Haibin, Ostroff, Gary R, Lee, Chrono K, Specht, Charles A, Levitz, Stuart M

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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One Step Purification-Vaccine Delivery System by Soto, Ernesto R, Specht, Charles A, Lee, Chrono K, Levitz, Stuart M, Ostroff, Gary R

“…Glucan particles (GPs) are hollow, porous 3-5 µm microspheres derived from the cell walls of Baker's yeast ( ). Their 1,3-β-glucan outer shell allows for…”
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Yeast Particle Encapsulation of Azole Fungicides for Enhanced Treatment of Azole-Resistant Candida albicans by Soto, Ernesto R, Rus, Florentina, Ostroff, Gary R

“…Addressing the growing problem of antifungal resistance in medicine and agriculture requires the development of new drugs and strategies to preserve the…”
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Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites by Hoang, Duy, Flanagan, Kelly, Ding, Qian, Cazeault, Nicholas R, Li, Hanchen, Díaz-Valerio, Stefani, Rus, Florentina, Darfour, Esther A, Kass, Elizabeth, Petersson, Katherine H, Nielsen, Martin K, Liesegang, Heiko, Ostroff, Gary R, Aroian, Raffi V

“…Bacillus thuringiensis crystal (Cry) proteins have been expressed in commercial transgenic crops for nearly 30 years, providing safe and effective control of…”
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Protection of Mice against Experimental Cryptococcosis by Synthesized Peptides Delivered in Glucan Particles by Specht, Charles A, Homan, E Jane, Lee, Chrono K, Mou, Zhongming, Gomez, Christina L, Hester, Maureen M, Abraham, Ambily, Rus, Florentina, Ostroff, Gary R, Levitz, Stuart M

“…The high global burden of cryptococcosis has made development of a protective vaccine a public health priority. We previously demonstrated that a vaccine…”
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Cross-reactivity between vaccine antigens from the chitin deacetylase protein family improves survival in a mouse model of cryptococcosis by Hester, Maureen M, Oliveira, Lorena V N, Wang, Ruiying, Mou, Zhongming, Lourenco, Diana, Ostroff, Gary R, Specht, Charles A, Levitz, Stuart M

“…Meningitis due to the fungal pathogen is estimated to cause nearly 200,000 deaths annually, mostly in resource-limited regions. We previously identified…”
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Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles by Whelan, Adam O, Flick-Smith, Helen C, Homan, Jane, Shen, Zu T, Carpenter, Zoe, Khoshkenar, Payam, Abraham, Ambily, Walker, Nicola J, Levitz, Stuart M, Ostroff, Gary R, Oyston, Petra C F

“…Francisella tularensis is an intracellular pathogen causing the disease tularemia, and an organism of concern to biodefence. There is no licensed vaccine…”
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Construction and Evaluation of a Novel Recombinant T Cell Epitope-Based Vaccine against Coccidioidomycosis by HURTGEN, Brady J, HUNG, Chiung-Yu, OSTROFF, Gary R, LEVITZ, Stuart M, COLE, Garry T

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles by De Jesus, Magdia, Ostroff, Gary R, Levitz, Stuart M, Bartling, Toni R, Mantis, Nicholas J

“…Glucan particles (GPs) are 2-4 μm hollow, porous shells composed of 1,3-β-D-glucan that have been effectively used for oral targeted-delivery of a wide range…”
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Robust stimulation of humoral and cellular immune responses following vaccination with antigen-loaded beta-glucan particles by Huang, Haibin, Ostroff, Gary R, Lee, Chrono K, Specht, Charles A, Levitz, Stuart M

“…beta-Glucan particles (GPs) are purified Saccharomyces cerevisiae cell walls treated so that they are primarily beta1,3-d-glucans and free of mannans and…”
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Distinct Patterns of Dendritic Cell Cytokine Release Stimulated by Fungal β-Glucans and Toll-Like Receptor Agonists by Huang, Haibin, Ostroff, Gary R, Lee, Chrono K, Wang, Jennifer P, Specht, Charles A, Levitz, Stuart M

“…β-Glucans derived from fungal cell walls have potential uses as immunomodulating agents and vaccine adjuvants. Yeast glucan particles (YGPs) are highly…”
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A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection by Noon, Jason B, Schwarz, Erich M, Ostroff, Gary R, Aroian, Raffi V

“…Human hookworms (Necator americanus, Ancylostoma duodenale, and Ancylostoma ceylanicum) are intestinal blood-feeding parasites that infect ~500 million people…”
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Glucan particles for selective delivery of siRNA to phagocytic cells in mice by Tesz, Gregory J, Aouadi, Myriam, Prot, Matthieu, Nicoloro, Sarah M, Boutet, Emilie, Amano, Shinya U, Goller, Anca, Wang, Mengxi, Guo, Chang-An, Salomon, William E, Virbasius, Joseph V, Baum, Rebecca A, O'Connor, Jr, Mark J, Soto, Ernesto, Ostroff, Gary R, Czech, Michael P

“…Phagocytic macrophages and dendritic cells are desirable targets for potential RNAi (RNA interference) therapeutics because they often mediate pathogenic…”
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