Search Results - "Ostroff, Gary"

β-Glucan microparticles are good candidates for mucosal antigen delivery in oral vaccination by De Smet, Rebecca, Demoor, Tine, Verschuere, Stephanie, Dullaers, Melissa, Ostroff, Gary R., Leclercq, Georges, Allais, Liesbeth, Pilette, Charles, Dierendonck, Marijke, De Geest, Bruno G., Cuvelier, Claude A.

“…Continuously improving the developmental process and the efficacy of oral vaccines is essential in the fight against intestinal pathogens. A promising strategy…”
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Yeast Particles for Encapsulation of Terpenes and Essential Oils by Soto, Ernesto R, Rus, Florentina, Mirza, Zeynep, Ostroff, Gary R

“…Terpenes and essential oils are materials of great commercial use due to their broad spectra of antibacterial, antifungal, membrane permeation enhancement and…”
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A glucan-particle based tularemia subunit vaccine induces T-cell immunity and affords partial protection in an inhalation rat infection model by Whelan, Adam O, Flick-Smith, Helen C, Walker, Nicola J, Abraham, Ambily, Levitz, Stuart M, Ostroff, Gary R, Oyston, Petra C F

“…Tularemia is a zoonotic disease caused by the facultative intracellular gram-negative bacterium Francisella tularensis. F. tularensis has a very low infection…”
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Spectrum and mechanisms of inflammasome activation by chitosan by Bueter, Chelsea L, Lee, Chrono K, Wang, Jennifer P, Ostroff, Gary R, Specht, Charles A, Levitz, Stuart M

“…Chitosan, the deacetylated derivative of chitin, can be found in the cell wall of some fungi and is used in translational applications. We have shown that…”
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Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation by Aouadi, Myriam, Tesz, Gregory J., Nicoloro, Sarah M., Wang, Mengxi, Chouinard, My, Soto, Ernesto, Ostroff, Gary R., Czech, Michael P.

“…Special delivery for siRNAs The therapeutic potential of gene silencing with siRNAs (short interfering RNAs) is great — in theory. In practice many obstacles…”
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Characterization of Multilayered Nanoparticles Encapsulated in Yeast Cell Wall Particles for DNA Delivery by Soto, Ernesto R, Ostroff, Gary R

“…Nonviral gene delivery technologies have been developed using layer-by-layer self-assembly of nanomaterials held together by electrostatic interactions in…”
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Yeast Particles Hyper-Loaded with Terpenes for Biocide Applications by Soto, Ernesto R, Rus, Florentina, Ostroff, Gary R

“…Yeast particles (YPs) are 3−5 µm hollow and porous microspheres, a byproduct of some food grade yeast (Saccharomyces cerevisiae) extract manufacturing…”
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Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens by Hester, Maureen M., Lee, Chrono K., Abraham, Ambily, Khoshkenar, Payam, Ostroff, Gary R., Levitz, Stuart M., Specht, Charles A.

“…•Cryptococcal protein antigens were recombinantly expressed in E. coli.•Two mouse strains were vaccinated with recombinant protein-filled glucan…”
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Protection induced by a Francisella tularensis subunit vaccine delivered by glucan particles by Whelan, Adam O, Flick-Smith, Helen C, Homan, Jane, Shen, Zu T, Carpenter, Zoe, Khoshkenar, Payam, Abraham, Ambily, Walker, Nicola J, Levitz, Stuart M, Ostroff, Gary R, Oyston, Petra C F

“…Francisella tularensis is an intracellular pathogen causing the disease tularemia, and an organism of concern to biodefence. There is no licensed vaccine…”
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A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles by De Jesus, Magdia, Ostroff, Gary R, Levitz, Stuart M, Bartling, Toni R, Mantis, Nicholas J

“…Glucan particles (GPs) are 2-4 μm hollow, porous shells composed of 1,3-β-D-glucan that have been effectively used for oral targeted-delivery of a wide range…”
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An efficient (nano) silica - In glucan particles protein encapsulation approach for improved thermal stability by Soto, Ernesto R., Specht, Charles A., Rus, Florentina, Lee, Chrono K., Abraham, Ambily, Levitz, Stuart M., Ostroff, Gary R.

“…Glucan particles (GPs) are hollow, porous microspheres derived from Saccharomyces cerevisiae (Baker's yeast). The hollow cavity of GPs allows for efficient…”
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A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection by Noon, Jason B, Schwarz, Erich M, Ostroff, Gary R, Aroian, Raffi V

“…Human hookworms (Necator americanus, Ancylostoma duodenale, and Ancylostoma ceylanicum) are intestinal blood-feeding parasites that infect ~500 million people…”
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One Step Purification-Vaccine Delivery System by Soto, Ernesto R, Specht, Charles A, Lee, Chrono K, Levitz, Stuart M, Ostroff, Gary R

“…Glucan particles (GPs) are hollow, porous 3-5 µm microspheres derived from the cell walls of Baker's yeast ( ). Their 1,3-β-glucan outer shell allows for…”
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Exploiting fungal cell wall components in vaccines by Levitz, Stuart M., Huang, Haibin, Ostroff, Gary R., Specht, Charles A.

“…Innate recognition of fungi leads to strong adaptive immunity. Investigators are trying to exploit this observation in vaccine development by combining…”
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Beta-glucan-induced inflammatory monocytes mediate antitumor efficacy in the murine lung by Alexander, Matthew P., Fiering, Steven N., Ostroff, Gary R., Cramer, Robert A., Mullins, David W.

“…β-Glucan is a naturally occurring glucose polysaccharide with immunostimulatory activity in both infection and malignancy. β-Glucan’s antitumor effects have…”
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HTT-lowering reverses Huntington's disease immune dysfunction caused by NFκB pathway dysregulation by TRÄGER, Ulrike, ANDRE, Ralph, MOSER, Roger, HUMMERICH, Holger, ANTONIOU, Michael, BATES, Gillian P, LUTHI-CARTER, Ruth, LOWDELL, Mark W, BJÖRKQVIST, Maria, OSTROFF, Gary R, ARONIN, Neil, TABRIZI, Sarah J, LAHIRI, Nayana, MAGNUSSON-LIND, Anna, WEISS, Andreas, GRUENINGER, Stephan, MCKINNON, Chris, SIRINATHSINGHJI, Eva, KAHLON, Shira, PFISTER, Edith L

“…Huntington's disease is an inherited neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin gene. The peripheral innate immune system…”
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Anthelmintic Activity of Yeast Particle-Encapsulated Terpenes by Mirza, Zeynep, Soto, Ernesto R, Hu, Yan, Nguyen, Thanh-Thanh, Koch, David, Aroian, Raffi V, Ostroff, Gary R

“…Soil-transmitted nematodes (STN) infect 1-2 billion of the poorest people worldwide. Only benzimidazoles are currently used in mass drug administration, with…”
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Characterization and Optimization of the Glucan Particle-Based Vaccine Platform by Huang, Haibin, Ostroff, Gary R, Lee, Chrono K, Specht, Charles A, Levitz, Stuart M

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection by Hung, Chiung-Yu, Zhang, Hao, Castro-Lopez, Natalia, Ostroff, Gary R, Khoshlenar, Payam, Abraham, Ambily, Cole, Garry T, Negron, Austin, Forsthuber, Thomas, Peng, Tao, Galgiani, John N, Ampel, Neil M, Yu, Jieh-Juen

“…Developing an effective and safe recombinant vaccine requires microbe-specific antigens combined with an adjuvant/delivery system to strengthen protective…”
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Yeast Particle Encapsulation of Azole Fungicides for Enhanced Treatment of Azole-Resistant Candida albicans by Soto, Ernesto R, Rus, Florentina, Ostroff, Gary R

“…Addressing the growing problem of antifungal resistance in medicine and agriculture requires the development of new drugs and strategies to preserve the…”
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