Search Results - "Osterloh, Jeannette M"

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    Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly by Neukomm, Lukas J., Burdett, Thomas C., Seeds, Andrew M., Hampel, Stefanie, Coutinho-Budd, Jaeda C., Farley, Jonathan E., Wong, Jack, Karadeniz, Yonca B., Osterloh, Jeannette M., Sheehan, Amy E., Freeman, Marc R.

    Published in Neuron (Cambridge, Mass.) (05-07-2017)
    “…Axon degeneration is a hallmark of neurodegenerative disease and neural injury. Axotomy activates an intrinsic pro-degenerative axon death signaling cascade…”
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    Manipulating cell fate while confronting reproducibility concerns by Osterloh, Jeannette M., Mullane, Kevin

    Published in Biochemical pharmacology (01-05-2018)
    “…[Display omitted] Biomedical research is being transformed by the discovery and use of human pluripotent stem cells (hPSCs). Remarkable progress has been made,…”
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    Neuronal death or dismemberment mediated by Sox14 by Osterloh, Jeannette M, Freeman, Marc R

    Published in Nature neuroscience (01-12-2009)
    “…The pruning of unneeded axons and dendrites is crucial for circuitry maturation, but poorly understood on the molecular level. During Drosophila metamorphosis,…”
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    Loss of Sarm1 does not suppress motor neuron degeneration in the SOD1G93A mouse model of amyotrophic lateral sclerosis by Peters, Owen M, Lewis, Elizabeth A, Osterloh, Jeannette M, Weiss, Alexandra, Salameh, Johnny S, Metterville, Jake, Brown, Robert H, Freeman, Marc R

    Published in Human molecular genetics (01-11-2018)
    “…Axon degeneration occurs in all neurodegenerative diseases, but the molecular pathways regulating axon destruction during neurodegeneration are poorly…”
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