Search Results - "Ostergaard, Sharon Dietz"
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Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model
Published in mSphere (03-02-2021)“…Smallpox, caused by (VARV), was eradicated in 1980; however, VARV bioterrorist threats still exist, necessitating readily available therapeutics. Current…”
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Teaching a new mouse old tricks: Humanized mice as an infection model for Variola virus
Published in PLoS pathogens (01-09-2021)“…Smallpox, caused by the solely human pathogen Variola virus (VARV), was declared eradicated in 1980. While known VARV stocks are secure, smallpox remains a…”
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Progestin‐based contraception regimens modulate expression of putative HIV risk factors in the vaginal epithelium of pig‐tailed Macaques
Published in American journal of reproductive immunology (1989) (01-10-2018)“…Problem In women, the use of progestin‐based contraception may increase the risk of vaginal HIV acquisition. We previously showed in macaques that there is a…”
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Correction for Hutson et al., "Pharmacokinetics and Efficacy of a Potential Smallpox Therapeutic, Brincidofovir, in a Lethal Monkeypox Virus Animal Model"
Published in mSphere (17-02-2021)Get full text
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A combined oral contraceptive affects mucosal SHIV susceptibility factors in a pigtail macaque (Macaca nemestrina) model
Published in Journal of medical primatology (01-04-2015)“…Background Injectable hormonal contraception may increase women's risk of HIV acquisition and can affect biological risk factors in animal models of HIV. We…”
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Use of live Variola virus to determine whether CAST/EiJ mice are a suitable surrogate animal model for human smallpox
Published in Virus research (02-01-2020)“…•Cast mice challenged with 105 or 106 pfu of variola virus(VARV) manifest mild clinical illness.•A greater number of younger animals had viable virus in their…”
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Relationship of Estimated SHIV Acquisition Time Points During the Menstrual Cycle and Thinning of Vaginal Epithelial Layers in Pigtail Macaques
Published in Sexually transmitted diseases (01-12-2015)“…BACKGROUNDHIV acquisition in the female genital tract remains incompletely understood. Quantitative data on biological HIV risk factors, the influence of…”
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