Search Results - "Ostankovitch, M"

Post-translational modifications of naturally processed MHC-binding epitopes by Engelhard, Victor H, Altrich-Vanlith, Michelle, Ostankovitch, Marina, Zarling, Angela L

“…A variety of different post-translational modifications of peptides displayed by class I and II MHC molecules have now been described. Some modifications…”
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CDR3 size analysis of T cell receptor V beta transcripts: follow-up study in a patient with T cell acute lymphoblastic leukemia by Prevost-Blondel, A, Ostankovitch, M, Melle, J, Pannetier, C, Macintyre, E, Dreyfus, F, Guillet, J G

“…T cell acute lymphoblastic leukemia (T-ALL) is generally considered to be a clonal disorder arising as an expansion of committed lymphoid precursors. The…”
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Regulated Folding of Tyrosinase in the Endoplasmic Reticulum Demonstrates That Misfolded Full-Length Proteins Are Efficient Substrates for Class I Processing and Presentation by Ostankovitch, Marina, Robila, Valentina, Engelhard, Victor H

“…Short-lived protein translation products have been proposed to be the principal substrates that enter the class I MHC processing and presentation pathway…”
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Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells by Lauvau, G, Kakimi, K, Niedermann, G, Ostankovitch, M, Yotnda, P, Firat, H, Chisari, F V, van Endert, P M

“…Antigen presentation by major histocompatibility complex (MHC) class I molecules requires peptide supply by the transporters associated with antigen processing…”
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Membrane-Bound Fas (Apo-1/CD95) Ligand on Leukemic Cells: A Mechanism of Tumor Immune Escape in Leukemia Patients by Buzyn, Agnès, Petit, Frederic, Ostankovitch, Marina, Figueiredo, Suzanne, Varet, Bruno, Guillet, Jean-Gérard, Ameisen, Jean-Claude, Estaquier, Jérôme

“…There is evidence from bone marrow transplantation that T cells may be involved in the immunologic control of leukemia. But many patients relapse despite a…”
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Peptides derived from the whole sequence of BCR-ABL bind to several class I molecules allowing specific induction of human cytotoxic T lymphocytes by Buzyn, A, Ostankovitch, M, Zerbib, A, Kemula, M, Connan, F, Varet, B, Guillet, J G, Choppin, J

“…Chronic myeloid leukemia (CML) is characterized cytogenetically by a t(9;22) translocation which generates a hybrid bcr-abl gene, encoding a p210(bcr-abl)…”
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A Partially Modified Retro-Inverso Pseudopeptide Modulates the Cytokine Profile of CTL Specific for an Influenza Virus Epitope by Ostankovitch, Marina, Guichard, Gilles, Connan, Francine, Muller, Sylviane, Chaboissier, Aude, Hoebeke, Johan, Choppin, Jeannine, Briand, Jean-Paul, Guillet, Jean-Gerard

“…There is considerable evidence that peptides corresponding to MHC class I-restricted epitopes can be used as immunogens or immunomodulators. Pseudopeptides…”
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Dendritic cells transfected with the nef genes of HIV‐1 primary isolates specifically activate cytotoxic T lymphocytes from seropositive subjects by Chassin, Dorine, Andrieu, Muriel, Cohen, William, Culmann‐Penciolelli, Béatrice, Ostankovitch, Marina, Hanau, Daniel, Guillet, Jean‐Gérard

“…The HIV‐1 Nef protein down‐modulates surface expression of MHC class I proteins. Primary infected T lymphocytes thus escape lysis by cytotoxic T lymphocytes…”
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Partially Modified Retro-Inverso Pseudopeptides as Non-natural Ligands for the Human Class I Histocompatibility Molecule HLA-A2 by Guichard, Gilles, Connan, Francine, Graff, Roland, Ostankovitch, Marina, Muller, Sylviane, Guillet, Jean-Gérard, Choppin, Jeannine, Briand, Jean-Paul

“…Syntheses of a series of partially modified retro-inverso analogues of the antigenic peptide M58-66 derived from the influenza virus matrix protein are…”
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Antileukemic HLA-restricted T-cell clones generated with naturally processed peptides eluted from acute myeloblastic leukemia blasts by OSTANKOVITCH, M, BUZYN, A, BONHOMME, D, CONNAN, F, BOUSCARY, D, HESHMATI, F, DREYFUS, F, CHOPPIN, J, GUILLET, J.-G

“…Recent studies have shown that transfusions of HLA-compatible donor lymphocytes may induce complete remission in marrow-grafted patients with relapses of acute…”
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Generation of Melan‐A/MART‐1‐specific CD8+ cytotoxic T lymphocytes from human naive precursors: Helper effect requirement for efficient primary cytotoxic T lymphocyte induction in vitro by Ostankovitch, Marina, Le Gal, Frédérique‐Anne, Connan, Francine, Chassin, Dorine, Choppin, Jeannine, Guillet, Jean‐Gérard

“…This study investigates the generation of primary melanoma cell‐specific cytotoxic T lymphocytes (CTLs) in vitro. Induction of peptide‐specific CTLs from…”
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Generation of Melan-A/MART-1-specific CD8 super(+) cytotoxic T lymphocytes from human naive precursors: Helper effect requirement for efficient primary cytotoxic T lymphocyte induction in vitro by Ostankovitch, M, Le Gal, F-A, Connan, F, Chassin, D, Choppin, J, Guillet, J-G

“…This study investigates the generation of primary melanoma cell-specific cytotoxic T lymphocytes (CTLs) in vitro. Induction of peptide-specific CTLs from…”
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HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4 by Houlgatte, R, Scarmato, P, el Marhomy, S, Martin, M, Ostankovitch, M, Lafosse, S, Vervisch, A, Auffray, C, Platier-Tonneau, D

“…Although the HIV gp120 binding site of CD4 is well characterized, its interaction site with HLA class II molecules is still controversial. Sixty-seven…”
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Membrane-Bound Fas (Apo-1/CD95) Ligand on Leukemic Cells: A Mechanism of Tumor Immune Escape in Leukemia Patients by Buzyn, Agnès, Petit, Frederic, Ostankovitch, Marina, Figueiredo, Suzanne, Varet, Bruno, Guillet, Jean-Gérard, Ameisen, Jean-Claude, Estaquier, Jérôme

“…There is evidence from bone marrow transplantation that T cells may be involved in the immunologic control of leukemia. But many patients relapse despite a…”
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Outlook for cellular adoptive or vaccine immunotherapy for chronic myeloid leukemia by Buzyn, A, Ostankovitch, M, Varet, B, Guillet, J G

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Perspectives d'immunothérapie des hémopathies malignes by BUZYN, A, OSTANKOVITCH, M, KEMULA, M, CHOPPIN, J, VARET, B, GUILLET, J.-G

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Tumor cell antigenicity: cancers and vaccines by Ostankovitch, M, Choppin, J, Guillet, J G

“…Tumor-specific immunity is partly linked to the observation that cancerous cells express some proteins that are not present in normal cells. In the past, one…”
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Immunité antitumorale et perspectives d'immunothérapie by OSTANKOVITCH, M, BUZYN, A, GNJATIC, S, CHOPPIN, J, GUILLET, J.-G

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