Search Results - "Ost, Anita"

Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Antioxidants & Redox Signaling by Öst, Anita

Get more information

Epigenetic modulation of metabolic decisions by Öst, Anita, Pospisilik, John Andrew

“…In the recent years there has been a tremendous increase in our understanding of chromatin, transcription and the importance of metabolites in their…”
Get full text

Human sperm displays rapid responses to diet by Nätt, Daniel, Kugelberg, Unn, Casas, Eduard, Nedstrand, Elizabeth, Zalavary, Stefan, Henriksson, Pontus, Nijm, Carola, Jäderquist, Julia, Sandborg, Johanna, Flinke, Eva, Ramesh, Rashmi, Örkenby, Lovisa, Appelkvist, Filip, Lingg, Thomas, Guzzi, Nicola, Bellodi, Cristian, Löf, Marie, Vavouri, Tanya, Öst, Anita

“…The global rise in obesity and steady decline in sperm quality are two alarming trends that have emerged during recent decades. In parallel, evidence from…”
Get full text

Paternal Diet Defines Offspring Chromatin State and Intergenerational Obesity by Öst, Anita, Lempradl, Adelheid, Casas, Eduard, Weigert, Melanie, Tiko, Theodor, Deniz, Merdin, Pantano, Lorena, Boenisch, Ulrike, Itskov, Pavel M., Stoeckius, Marlon, Ruf, Marius, Rajewsky, Nikolaus, Reuter, Gunter, Iovino, Nicola, Ribeiro, Carlos, Alenius, Mattias, Heyne, Steffen, Vavouri, Tanya, Pospisilik, J. Andrew

“…The global rise in obesity has revitalized a search for genetic and epigenetic factors underlying the disease. We present a Drosophila model of…”
Get full text

Seqpac: a framework for sRNA-seq analysis in R using sequence-based counts by Skog, Signe, Örkenby, Lovisa, Kugelberg, Unn, Öst, Anita, Nätt, Daniel

“…Abstract Motivation Feature-based counting is commonly used in RNA-sequencing (RNA-seq) analyses. Here, sequences must align to target features (like genes or…”
Get full text

Dietary Sugar Shifts Mitochondrial Metabolism and Small RNA Biogenesis in Sperm by Ramesh, Rashmi, Skog, Signe, Örkenby, Lovisa, Kugelberg, Unn, Nätt, Daniel, Öst, Anita

“…Increasing concentrations of dietary sugar results in a linear accumulation of triglycerides in male while inducing a U-shaped obesity response in their…”
Get more information

Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes by Ost, Anita, Svensson, Kristoffer, Ruishalme, Iida, Brännmark, Cecilia, Franck, Niclas, Krook, Hans, Sandström, Per, Kjolhede, Preben, Strålfors, Peter

“…Type 2 diabetes (T2D) is strongly linked to obesity and an adipose tissue unresponsive to insulin. The insulin resistance is due to defective insulin…”
Get full text

The concentration of β-carotene in human adipocytes, but not the whole-body adipocyte stores, is reduced in obesity by Östh, Martin, Öst, Anita, Kjolhede, Preben, Strålfors, Peter

“…We have examined the concentration of β-carotene in the fat of isolated abdominal subcutaneous adipocytes obtained from lean (BMI<23 kg/m²), non-obese with…”
Get full text

5´XP sRNA-seq: efficient identification of transcripts with and without 5´ phosphorylation reveals evolutionary conserved small RNA by Kugelberg, Unn, Nätt, Daniel, Skog, Signe, Kutter, Claudia, Öst, Anita

“…Small RNA (sRNA) sequencing has been critical for our understanding of many cellular processes, including gene regulation. Nonetheless, the varying biochemical…”
Get full text

Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis by Örkenby, Lovisa, Skog, Signe, Ekman, Helen, Gozzo, Alessandro, Kugelberg, Unn, Ramesh, Rashmi, Magadi, Srivathsa, Zambanini, Gianluca, Nordin, Anna, Cantú, Claudio, Nätt, Daniel, Öst, Anita

“…Early‐life stress can result in life‐long effects that impact adult health and disease risk, but little is known about how such programming is established and…”
Get full text

Retinol-binding protein-4 attenuates insulin-induced phosphorylation of IRS1 and ERK1/2 in primary human adipocytes by Öst, Anita, Danielsson, Anna, Lidén, Martin, Eriksson, Ulf, Nystrom, Fredrik H, Strålfors, Peter

“…Reduced sensitivity to insulin in adipose, muscle, and liver tissues is a hallmark of type 2 diabetes. Animal models and patients with type 2 diabetes exhibit…”
Get full text

Triacylglycerol Is Synthesized in a Specific Subclass of Caveolae in Primary Adipocytes by Öst, Anita, Örtegren, Unn, Gustavsson, Johanna, Nystrom, Fredrik H., Strålfors, Peter

“…A principal metabolic function of adipocytes is to synthesize triacylglycerol (TG) from exogenous fatty acids. The level of fatty acids has to be tightly…”
Get full text

A new role for caveolae as metabolic platforms by Örtegren, Unn, Aboulaich, Nabila, Öst, Anita, Strålfors, Peter

“…The plasma membrane of cells functions as a barrier to the environment. Caveolae are minute invaginations of the membrane that selectively carry out the…”
Get full text

Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level of phosphorylation of IRS1 in type 2 diabetes by Danielsson, Anna, Öst, Anita, Lystedt, Erika, Kjolhede, Preben, Gustavsson, Johanna, Nystrom, Fredrik H., Strålfors, Peter

“…Insulin resistance is a cardinal feature of type 2 diabetes and also a consequence of trauma such as surgery. Directly after surgery and cell isolation,…”
Get full text

Short-term overeating induces insulin resistance in fat cells in lean human subjects by Danielsson, Anna, Fagerholm, Siri, Ost, Anita, Franck, Niclas, Kjolhede, Preben, Nystrom, Fredrik H, Strålfors, Peter

“…Insulin resistance and type 2 diabetes (T2D) are closely linked to obesity. Numerous prospective studies have reported on weight gain, insulin resistance, and…”
Get full text

Attenuation of Insulin-stimulated Insulin Receptor Substrate-1 Serine 307 Phosphorylation in Insulin Resistance of Type 2 Diabetes by Danielsson, Anna, Öst, Anita, Nystrom, Fredrik H., Strålfors, Peter

“…Insulin resistance is a primary characteristic of type 2 diabetes and likely causally related to the pathogenesis of the disease. It is a result of defects in…”
Get full text

Separation and characterization of caveolae subclasses in the plasma membrane of primary adipocytes; segregation of specific proteins and functions by Örtegren, Unn, Yin, Lan, Öst, Anita, Karlsson, Helen, Nystrom, Fredrik H., Strålfors, Peter

“…Caveolae are nearly ubiquitous plasma membrane domains that in adipocytes vary in size between 25 and 150 nm. They constitute sites of entry into the cell as…”
Get full text

Colocalization of insulin receptor and insulin receptor substrate-1 to caveolae in primary human adipocytes. Cholesterol depletion blocks insulin signalling for metabolic and mitogenic control by Karlsson, Margareta, Thorn, Hans, Danielsson, Anna, Stenkula, Karin G, Ost, Anita, Gustavsson, Johanna, Nystrom, Fredrik H, Strålfors, Peter

“…Caveolae are plasma membrane invaginations with several functions, one of which appears to be to organize receptor mediated signalling. Here we report that in…”
Get full text

Male reproductive health and intergenerational metabolic responses from a small RNA perspective by Nätt, D., Öst, A.

“…The world has recently experienced a decline in male reproductive (e.g. sperm counts and motility) and metabolic (e.g. obesity and diabetes) health…”
Get full text

Colocalization of insulin receptor and insulin receptor substrate‐1 to caveolae in primary human adipocytes by Karlsson, Margareta, Thorn, Hans, Danielsson, Anna, Stenkula, Karin G., Öst, Anita, Gustavsson, Johanna, Nystrom, Fredrik H., Strålfors, Peter

“…Caveolae are plasma membrane invaginations with several functions, one of which appears to be to organize receptor mediated signalling. Here we report that in…”
Get full text