Search Results - "Ossipov, Dmitri"
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Nanostructured hyaluronic acid-based materials for active delivery to cancer
Published in Expert opinion on drug delivery (01-06-2010)“…Active targeting of bioactive molecules by physicochemical association with hyaluronic acid (HA) is an attractive approach in current nanomedicine because HA…”
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Bisphosphonate-modified biomaterials for drug delivery and bone tissue engineering
Published in Expert opinion on drug delivery (2015)“…Bisphosphonates (BPs) were introduced 45 years ago as anti-osteoporotic drugs and during the last decade have been utilized as bone-targeting groups in…”
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Self‐Healing Silk Fibroin‐Based Hydrogel for Bone Regeneration: Dynamic Metal‐Ligand Self‐Assembly Approach
Published in Advanced functional materials (05-10-2017)“…Despite advances in the development of silk fibroin (SF)‐based hydrogels, current methods for SF gelation show significant limitations such as lack of…”
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Hyaluronic acid-fibrin interpenetrating double network hydrogel prepared in situ by orthogonal disulfide cross-linking reaction for biomedical applications
Published in Acta biomaterialia (01-07-2016)“…[Display omitted] To strengthen the mechanical properties of a fibrin gel and improve its applicability as a scaffold for tissue engineering (TE) applications,…”
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Dynamic Coordination Chemistry Enables Free Directional Printing of Biopolymer Hydrogel
Published in Chemistry of materials (25-07-2017)“…Three-dimensional (3D) printing is a promising technology to develop customized biomaterials in regenerative medicine. However, for the majority of printable…”
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Bisphosphonate nanoclay edge-site interactions facilitate hydrogel self-assembly and sustained growth factor localization
Published in Nature communications (13-03-2020)“…Nanoclays have generated interest in biomaterial design for their ability to enhance the mechanics of polymeric materials and impart biological function. As…”
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Self‐Healing Polymeric Hydrogel Formed by Metal–Ligand Coordination Assembly: Design, Fabrication, and Biomedical Applications
Published in Macromolecular rapid communications. (01-04-2019)“…Self‐healing hydrogels based on metal–ligand coordination chemistry provide new and exciting properties that improve injectability, rheological behaviors, and…”
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Hyaluronic Acid Hydrogels Formed in Situ by Transglutaminase-Catalyzed Reaction
Published in Biomacromolecules (09-05-2016)“…Enzymatically cross-linked hydrogels can be formed in situ and permit highly versatile and selective tethering of bioactive molecules, thereby allowing for a…”
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A Modular Approach to Sensitized Two‐Photon Patterning of Photodegradable Hydrogels
Published in Angewandte Chemie International Edition (12-11-2018)“…Photodegradable hydrogels have emerged as useful platforms for research on cell function, tissue engineering, and cell delivery as their physical and chemical…”
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Moldable Hyaluronan Hydrogel Enabled by Dynamic Metal–Bisphosphonate Coordination Chemistry for Wound Healing
Published in Advanced healthcare materials (01-03-2018)“…Biomaterial‐based regenerative approaches would allow for cost‐effective off‐the‐shelf solution for the treatment of wounds. Hyaluronan (HA)‐based hydrogel is…”
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Poly(vinyl alcohol)-Based Hydrogels Formed by “Click Chemistry”
Published in Macromolecules (07-03-2006)“…Novel poly(vinyl alcohols) (PVA) functionalized with pendant acetylene and azide groups were prepared by carbonyldiimidazole (CDI)-mediated couplings of the…”
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Hyaluronan-based delivery of therapeutic oligonucleotides for treatment of human diseases
Published in Expert opinion on drug delivery (03-06-2019)“…Oligonucleotide therapeutics such as antisense oligonucleotides and siRNA requires chemical modifications and nano-sized carriers to circumvent stability…”
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Non-invasive in vitro and in vivo monitoring of degradation of fluorescently labeled hyaluronan hydrogels for tissue engineering applications
Published in Acta biomaterialia (2016)“…[Display omitted] Tracking of degradation of hydrogels-based biomaterials in vivo is very important for rational design of tissue engineering scaffolds that…”
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Injectable hyaluronic acid hydrogels with the capacity for magnetic resonance imaging
Published in Carbohydrate polymers (01-10-2018)“…[Display omitted] •Gadolinium complex modified with “clickable” dithiopyridyl groups was linked to thiolated hyaluronic acid (HA).•Gd-labeled HA was used as an…”
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Bone reservoir: Injectable hyaluronic acid hydrogel for minimal invasive bone augmentation
Published in Journal of controlled release (10-06-2011)“…A strategy has been designed to develop hyaluronic acid (HA) hydrogel for in vivo bone augmentation using minimal invasive technique. A mild synthetic…”
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Biocompatible Injectable Magnetic Hydrogel Formed by Dynamic Coordination Network
Published in ACS applied materials & interfaces (11-12-2019)“…Magnetic hydrogel that can respond to a magnetic stimulus is a promising biomaterial for tissue regeneration and cancer treatment. In this study, a novel…”
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Self-assembled hyaluronic acid nanoparticles for controlled release of agrochemicals and diosgenin
Published in Carbohydrate polymers (01-10-2017)“…•Hyaluronic acid (HA) derivatives were functionalized with bioactive steroids.•Synthesized conjugates formed self-assembled nanoparticles in aqueous…”
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In Situ Cross-Linkable High Molecular Weight Hyaluronan−Bisphosphonate Conjugate for Localized Delivery and Cell-Specific Targeting: A Hydrogel Linked Prodrug Approach
Published in Journal of the American Chemical Society (01-07-2009)“…We present here a novel synthesis route to functionalize high molecular weight hyaluronan (HMW-HA) with a hydrazide group and a bioactive ligand, namely…”
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Improving the osteogenic potential of BMP-2 with hyaluronic acid hydrogel modified with integrin-specific fibronectin fragment
Published in Biomaterials (01-01-2013)“…Abstract While human bone morphogenetic protein-2 (rhBMP-2) is a promising growth factor for bone regeneration, its clinical efficacy has recently shown to be…”
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Differentiating Co-Delivery of Bisphosphonate and Simvastatin by Self-Healing Hyaluronan Hydrogel Formed by Orthogonal “Clicks”: An In-Vitro Assessment
Published in Polymers (26-06-2021)“…Due to its unique properties resembling living tissues, hydrogels are attractive carriers for the localized and targeted delivery of various drugs. Drug…”
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