Search Results - "Ospelnikova, T P"
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Biological activity of interferons in the novel coronavirus infection COVID-19
Published in Voprosy virusologiĭ (05-05-2022)“…Introduction. The immunopathogenesis of the novel coronavirus infection COVID-19 is usually associated with the development of imbalance in the immune response…”
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Interferon-regulating activity of the celagrip antiviral drug and its influence on formation of reactive oxygen species and expression of innate immunity genes in the follicular lymphoma patients
Published in Voprosy virusologiĭ (15-11-2020)“…Introduction. Medicines from the group of interferon inducers (IFNs) “swith on” the synthesis of type 1 interferons (IFN-I) and induce the expression of…”
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Neuroinflammation in the Pathogenesis of Neuropathic Pain Syndrome
Published in Neuroscience and behavioral physiology (2023)“…The problem of chronic pain is relevant in modern medicine due to its high prevalence and, in many cases, the low efficacy of available treatment methods…”
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Interferon status as a method of determination of nonspecific biomarkers of human immunopathology
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (22-08-2019)“…For more than 60 years, the study of interferons (IFN) system has continued, as a complex network system. IFNs of 3 types are discovered: I (α/β), II (ƴ), III…”
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Interferon status in estimating the therapy of bronchial asthma with immunomodulating preparations
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (21-08-2019)“…Aim: to investigate the violations of the interferon status and to evaluate the clinical and immunological efficacy of immunoactive drugs in patients with…”
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Cytokine-regulating activity of anti-virus preparation CelAgripus in Burkitt's lym-phoma stable B-cell lines
Published in Voprosy virusologiĭ (20-08-2019)“…Introduction. Cytokines activated in response to immunosuppressive viral infections can directly or indirectly affect the neoplastic transformation of B cells…”
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INFLUENZA INFLAMMATION BIOMARKERS FEATURES
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-08-2019)“…Aim. Analysis of inflammation biomarkers using reverse transcription with real time PCR (RT-PCR-RT) and multiplex immunofluorescent analysis xMAP with magnetic…”
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Cytokine-regulating activity of anti-virus preparation CelAgripus in Burkitt's lymphoma stable B-cell lines.
Published in Voprosy virusologii (2019)“…Cytokines activated in response to immunosuppressive viral infections can directly or indirectly affect the neoplastic transformation of B cells. In this…”
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Microbiological features of bronchial asthma and chronic obstructive pulmonary disease during remission
Published in Kliničeskaâ praktika (15-12-2018)“…Background: Bronchial asthma and chronic obstructive pulmonary disease are currently the fifth leading cause of death in the world. The combination of…”
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THERAPEUTIC POTENTIAL OF ALPHA-INTERFERON PREPARATIONS DURING SOCIALLY-SIGNIFICANT HUMAN DISEASES OF VIRAL ETIOLOGY
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (28-10-2016)“…Interferons (IFN) belong to key cytokine? of innate and adaptive immune response and play an important role in anti-viral and anti-tumor protection. At the…”
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THE MICROBIOTA OF LOWER AIRWAYS IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASES
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (28-10-2018)“…Aim. We aimed to estimate the composition and the detection frequency of bacterial species in induced sputum samples from patients with bronchial asthma (BA),…”
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Development of hybrid human interferon alfa-2 strain-producers and the use of enteropeptidase for production of N-terminal methionine-free interferons
Published in Molecular biology (New York) (01-06-2011)“…We developed a technique for production of human interferon-α2a (IFN-α2a) and IFN-α2b lacking the N-terminal methionine. First of all, we constructed plasmids…”
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Detection of the interferon deficiency in inflammatory gynecological diseases and its correction with interferon inducers
Published in Georgian medical news (01-11-2012)“…Interferons deficiency has a negative influence on the development of infection and inflammation in general. The use in the complex of anti-inflammatory…”
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Comparative assessment of interferon activity in influenza and COVID-19
Published in Infekt͡s︡ii͡a︡ i immunitet (28-07-2024)“…Among respiratory viruses, the most serious complications are caused by influenza A and B viruses, as well as coronaviruses. Most studies determined the…”
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THE INFLUENCE OF NEUTRALIZING ANTIBODIES TO INTERFERON-BETA ON PROGRESSION OF MULTIPLE SCLEROSIS
Published in Alʹmanakh klinicheskoĭ medit͡s︡iny (01-07-2016)“…Background: Neutralizing antibodies (NAbs) affect the effectiveness of interferon therapy in patients with multiple sclerosis; however, this influence cannot…”
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Interferon system in patients with rheumatoid arthritis infected with hepatitis В and С viruses
Published in Nauchno-prakticheskai͡a︡ revmatologii͡a (15-08-2003)“…Interferon system in patients with rheumatoid arthritis infected with hepatitis В and С viruses. R.M. Balabanova, E. V. Vratskih, T.P. Ospelnikova, V.l…”
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THERAPEUTIC POTENTIAL OF ALPHA-INTERFERON PREPARATIONS DUR- ING SOCIALLY-SIGNIFICANT HUMAN DISEASES OF VIRAL ETIOLOGY
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-09-2016)“…Interferons (IFN) belong to key cytokines of innate and adaptive immune response and play an important role in anti-viral and anti-tumor protection. At the…”
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19
Dynamics of interferon status in patients with atopic dermatitis during standard therapy combined with cycloferon
Published in Klinicheskaia meditsina (2011)“…Interferon status at different stages of atopic dermatitis was evaluated in 28 patients. Its dynamics and disturbances during standard therapy combined with…”
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Designing of hybrid human interferon alfa-2 strain-producers and the use of enteropeptidase for obtaining N-terminal methionine-free interferons
Published in Molekuliarnaia biologiia (01-05-2011)“…A system for production of human interferon-alpha2a (IFN-alpha2a) and IFN-alpha2b lacking N-terminal methionine has been developed. Plasmids containing genes…”
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