Search Results - "Osorno, Tomas"
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A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types
Published in Nature (London) (07-10-2021)“…The cerebellar cortex is a well-studied brain structure with diverse roles in motor learning, coordination, cognition and autonomic regulation. However, a…”
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2
Ephaptic Coupling Promotes Synchronous Firing of Cerebellar Purkinje Cells
Published in Neuron (Cambridge, Mass.) (07-11-2018)“…Correlated neuronal activity at various timescales plays an important role in information transfer and processing. We find that in awake-behaving mice, an…”
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Cerebellum-Specific Deletion of the GABAA Receptor δ Subunit Leads to Sex-Specific Disruption of Behavior
Published in Cell reports (Cambridge) (03-11-2020)“…Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABAA subunit-containing GABAA receptors (δGABAARs) that respond to ambient GABA…”
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4
Light control of G protein signaling pathways by a novel photopigment
Published in PloS one (01-10-2018)“…Channelopsins and photo-regulated ion channels make it possible to use light to control electrical activity of cells. This powerful approach has lead to a…”
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5
Molecular and functional identification of a novel photopigment in Pecten ciliary photoreceptors
Published in The Journal of general physiology (05-03-2018)“…The two basic animal photoreceptor types, ciliary and microvillar, use different light-transduction schemes: their photopigments couple to G versus G proteins,…”
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6
Calcium activates the light-dependent conductance in melanopsin-expressing photoreceptors of amphioxus
Published in Proceedings of the National Academy of Sciences - PNAS (23-06-2015)“…Significance âCircadianâ photoreceptors of the mammalian retina use melanopsin, a photopigment that resembles invertebrate opsins and has widespread…”
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Candelabrum cells are ubiquitous cerebellar cortex interneurons with specialized circuit properties
Published in Nature neuroscience (01-06-2022)“…To understand how the cerebellar cortex transforms mossy fiber (MF) inputs into Purkinje cell (PC) outputs, it is vital to delineate the elements of this…”
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Cerebellum-Specific Deletion of the GABA A Receptor δ Subunit Leads to Sex-Specific Disruption of Behavior
Published in Cell reports (Cambridge) (03-11-2020)“…Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABA subunit-containing GABA receptors (δGABA Rs) that respond to ambient GABA levels…”
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Author Correction: A transcriptomic atlas of mouse cerebellar cortex comprehensively defines cell types
Published in Nature (London) (10-02-2022)Get full text
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10
Specialized connectivity of molecular layer interneuron subtypes leads to disinhibition and synchronous inhibition of cerebellar Purkinje cells
Published in Neuron (Cambridge, Mass.) (17-07-2024)“…Molecular layer interneurons (MLIs) account for approximately 80% of the inhibitory interneurons in the cerebellar cortex and are vital to cerebellar…”
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Novel Inhibitory Interneurons of the Cerebellar Cortex
Published 01-01-2022“…The cerebellum is a brain structure important for motor, social and cognitive behaviors. Its main processing unit, the cerebellar cortex, has a simple circuit…”
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Dissertation