Search Results - "Osorio, Jhon Carlos Castaño"

Antiviral Activity of an Indole-Type Compound Derived from Natural Products, Identified by Virtual Screening by Interaction on Dengue Virus NS5 Protein by García-Ariza, Leidy Lorena, González-Rivillas, Natalia, Díaz-Aguirre, Cindy Johanna, Rocha-Roa, Cristian, Padilla-Sanabria, Leonardo, Castaño-Osorio, Jhon Carlos

“…Dengue is an acute febrile illness caused by the Dengue virus (DENV), with a high number of cases worldwide. There is no available treatment that directly…”
Get full text

Assessment of Antimicrobial and Cytotoxic Activities of Liposomes Loaded with Curcumin and Lippia origanoides Essential Oil by Bedoya-Agudelo, Juan Pablo, López-Carvajal, Jhon Esteban, Quiguanás-Guarín, Edwin Stiven, Cardona, Nestor, Padilla-Sanabria, Leonardo, Castaño-Osorio, Jhon Carlos

“…(1) Introduction: Curcumin and essential oils have a broad spectrum of biological activities; however, their physicochemical instability, low solubility, and…”
Get full text

In Vitro Inhibition of Replication of Dengue Virus Serotypes 1-4 by siRNAs Bound to Non-Toxic Liposomes by Rodriguez-Salazar, Carlos Andrés, Recalde-Reyes, Delia Piedad, Bedoya, Juan Pablo, Padilla-Sanabria, Leonardo, Castaño-Osorio, Jhon Carlos, Giraldo, Maria Isabel

“…Dengue virus is a ssRNA+ flavivirus, which produces the dengue disease in humans. Currently, no specific treatment exists. siRNAs regulate gene expression and…”
Get full text

Characterization of six Shiga toxin-producing Escherichia coli (STEC) strains carrying Stx2-phages from Colombia by Arango, Brayan Stiven, Peña Buitrago, Sebastián, Castaño Osorio, Jhon Carlos, Granobles Velandia, Claudia Viviana

“…Shiga toxin producing Escherichia coli (STEC) is a bacterial pathogen that causes diarrhea and severe human diseases like HUS; its main virulence factor are…”
Get full text

PD1 CD44 antiviral peptide as an inhibitor of the protein-protein interaction in dengue virus invasion by Recalde-Reyes, Delia Piedad, Rodríguez-Salazar, Carlos Andrés, Castaño-Osorio, Jhon Carlos, Giraldo, María Isabel

“…Dengue virus (DENV) infection is mediated by the interaction between the virus envelope protein and cellular receptors of the host cells. In this study, we…”
Get full text

K48-linked polyubiquitination of dengue virus NS1 protein inhibits its interaction with the viral partner NS4B by Giraldo, Maria Isabel, Vargas-Cuartas, Oscar, Gallego-Gomez, Juan Carlos, Shi, Pei-Yong, Padilla-Sanabria, Leonardo, Castaño-Osorio, Jhon Carlos, Rajsbaum, Ricardo

“…•Bioinformatics and mass spectrometry analysis identified ubiquitination of multiple lysine residues on DENV-NS1.•Dengue NS1 undergoes modification by…”
Get full text

Novel antimicrobial cecropins derived from O. curvicornis and D. satanas dung beetles by Henao Arias, Diana Carolina, Toro, Lily Johana, Téllez Ramirez, Germán Alberto, Osorio-Méndez, Juan Felipe, Rodríguez-Carlos, Adrián, Valle, Javier, Marín-Luevano, Sara Paulina, Rivas-Santiago, Bruno, Andreu, David, Castaño Osorio, Jhon Carlos

“…•The peptides satanin 1, 2, and curvicin are new Scarabaeidae cecropin from O. curvicornis and D. satanas.•Satanin 1, 2, and curvicin are cationic alpha…”
Get full text

Antiparasitic phytotherapy perspectives, scope and current development by Castaño Osorio, Jhon Carlos, Giraldo García, Alejandra María

“…Abstract Tropical protozoan diseases are currently a major public health problem throughout the world and are strongly linked with poverty, this combined with…”
Get full text

Identification and characterization of novel cecropins from the Oxysternon conspicillatum neotropic dung beetle by Toro Segovia, Lily Johanna, Téllez Ramírez, Germán Alberto, Henao Arias, Diana Carolina, Rivera Duran, Juan David, Bedoya, Juan Pablo, Castaño Osorio, Jhon Carlos

“…Dung beetles are exposed to a complex microbiological ecosystem during their life cycle. Characterization of novel host-defense peptides (HDP) is essential to…”
Get full text

Development of a Dengue Vaccine and Its Use in Pregnant Women by Giraldo-García, Alejandra María, Castaño-Osorio, Jhon Carlos

“…Purpose of Review This article discusses dengue virus infection, its effects on mothers and their infants during pregnancy, and the significant issues…”
Get full text

Determination of pyrrolizidine alkaloids in comfrey by liquid chromatography–electrospray ionization mass spectrometry by Liu, Feng, Wan, Sow Yin, Jiang, Zhangjian, Li, Sam Fong Yau, Ong, Eng Shi, Osorio, Jhon Carlos Castaño

“…Symphytum officinale L. (comfrey) is a medicinal plant commonly used in decoctions and aliments. Besides therapeutic bioactive compounds present in the herb,…”
Get full text

New Insect Host Defense Peptides (HDP) From Dung Beetle (Coleoptera: Scarabaeidae) Transcriptomes by Téllez Ramirez, Germán Alberto, Osorio-Méndez, Juan Felipe, Henao Arias, Diana Carolina, Toro S., Lily Johanna, Franco Castrillón, Juliana, Rojas-Montoya, Maribel, Castaño Osorio, Jhon Carlos

“…Abstract The Coleoptera Scarabaeidae family is one of the most diverse groups of insects on the planet, which live in complex microbiological environments…”
Get full text

Expression and purification of an active cecropin-like recombinant protein against multidrug resistance Escherichia coli by Téllez, Germán Alberto, Castaño-Osorio, Jhon Carlos

“…•An antimicrobial protein derived from the cecropin Lucilin was expressed in E. coli.•The purified recombinant protein is active against E. coli with ESBL.•The…”
Get full text

CONTRIBUCIÓN AL ESTUDIO FITOQUÍMICO DE LA ESPECIE “Sansevieria trifasciata Prain” Y SU COMPORTAMIENTO FRENTE A ENSAYOS BIOLOGICOS by Molina-Fajardo, Ludy, Gómez-Barreraa, Milton, Castaño-Osorio, Jhon Carlos

“…Se evaluaron  las  diferentes propiedades biológicas de los  extracto total , etanólico y la fracción alcaloidal de hojas de Sansevieria trifasciata, como la…”
Get full text

VIRUS Y ENFERMEDADES CRÓNICAS by Castaño Osorio, Jhon Carlos

“…Los virus como agentes infecciosos cada día se implican en la fisiopatogenesis de un sin número de enfermedades crónicas, de diversos espectros clínicos que…”
Get full text

Effects of Flavivirus Cross-Reactivity (Zika and Dengue) on the Development of Vaccines for Use in Pregnancy by Giraldo-García, Alejandra María, Castaño-Osorio, Jhon Carlos

“…Purpose of Review The aim of this article is to discuss the implications of immunological cross-reactivity with other prevalent flaviviruses, such as DENV, for…”
Get full text

Manifestaciones clínicas y hallazgos de laboratorio de una serie de casos febriles agudos con diagnóstico presuntivo de infección por el virus dengue. Quindío (Colombia) by Rodríguez-Salazar, Carlos Andrés, Recalde-Reyes, Delia Piedad, González, María Mercedes, Padilla Sanabria, Leonardo, Quintero-Álvarez, Liliana, Gallego-Gómez, Juan Carlos, Castaño-Osorio, Jhon Carlos

“…Describir las manifestaciones clínicas y hallazgos de laboratorio de una serie de casos febriles agudos con diagnóstico presuntivo de infección por el virus…”
Get full text

Presentación de un caso de queratitis por Acanthamoeba, su aislamiento clínico y tratamiento exitoso con antisépticos en el departamento del Quindío, y revisión de la literatura by Jhon Carlos Castaño-Osorio

“…La queratitis por Acanthamoeba es una entidad clínica cuya incidencia se ha venido incrementando recientemente, debido al uso de lentes de contacto blandos. En…”
Get full text

Inmunización intranasal de ratones con la proteína SAG2 de Toxoplasma gondii asociada con la toxina colérica by Jhon Carlos Castaño Osorio, Jorge Sarracent Pérez

“…Se estudió la capacidad como inmunógeno de la proteína SAG2 nativa del taquizoíto de T. gondii administrada por vía intranasal asociada con toxina colérica en…”
Get full text

Prevalencia de Fasciola hepatica, en humanos y bovinos en el departamento del Quindío-Colombia 2012-2013 by Recalde-Reyes, Delia Piedad, Padilla Sanabria, Leonardo, Giraldo Giraldo, María Isabel, Toro Segovia, Lily Johana, Gonzalez, María Mercedes, Castaño Osorio, Jhon Carlos

“…La fasciolosis es una parasitosis causada por Fasciola hepatica (F. hepatica). En el departamento del Quindío se desconoce su prevalencia tanto en humanos como…”
Get full text