Search Results - "Osmond, Daniel H."
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Angiotensin converting enzyme-regulated, noncholinergic sympathoadrenal catecholamine release mediates the cardiovascular actions of human ‘new pressor protein’ related to coagulation beta-factor XIIa
Published in Canadian journal of cardiology (01-04-2009)“…Background Human ‘new pressor protein’ (NPP), related to coagulation beta-factor XIIa (β-FXIIa), potently releases sympathoadrenal catecholamines in bioassay…”
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Characterization of Apelin, the Ligand for the APJ Receptor
Published in Journal of neurochemistry (01-01-2000)“…: The apelin peptide was recently discovered and demonstrated to be the endogenous ligand for the G protein‐coupled receptor, APJ. A search of the GenBank…”
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Role of bradykinin B2-receptor in the sympathoadrenal effects of ‘new pressor protein’ related to human blood coagulation factor XII fragment
Published in Journal of hypertension (01-06-2004)“…Background Human plasma new pressor protein (NPP) increases blood pressure, heart rate and plasma adrenal medullary catecholamines in bioassay rats – all…”
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Are cardiovascular and sympathoadrenal effects of human "new pressor protein" preparations attributable to human coagulation beta-FXIIa?
Published in American journal of physiology. Heart and circulatory physiology (01-03-2004)“…"New pressor protein" (NPP) derived from normal human plasma is an extra renal enzyme that shares strong sequence homology with human coagulation beta-FXIIa…”
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Human coagulation factor XII-related "new pressor protein": role of PACAP in its cardiovascular and sympathoadrenal effects
Published in Canadian journal of cardiology (01-10-2002)“…To investigate the role of pituitary adenylate cyclase-activating polypeptide (PACAP)-38 and -27 as possible mediators of the actions of "new pressor protein"…”
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The sympathoadrenal system mediates the blood pressure and cardiac effects of human coagulation factor XII-related "new pressor protein"
Published in Canadian journal of cardiology (01-10-2002)“…To investigate the major cardiovascular effects of human plasma "new pressor protein" (NPP) and how the adrenal medulla contributes to these effects. NPP was…”
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Possible role of new pressor protein in hypertensive anephric hemodialysis patients
Published in Pediatric nephrology (Berlin, West) (01-10-2003)“…Unexplained hypertension was observed in three anephric children on hemodialysis. We investigated the possible involvement of a novel hypertensive extra-renal…”
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P-552: Elevated plasma coagulation FXIIA levels and high ‘new pressor protein’ (npp) activity in pediatric hemodialysis patients with unexplained renoprival hypertension
Published in American journal of hypertension (01-05-2003)“…Unexplained hypertension was observed in three anephric children on hemodialysis. We therefore investigated possible involvement by the novel extra-renal…”
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Possible role of new pressor protein in hypertensive anephric hemodialysis patients
Published in Pediatric nephrology (Berlin, West) (01-12-2003)Get full text
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Plasma prorenin as an early marker of nephropathy in diabetic (IDDM) adolescents
Published in Kidney international (01-10-1994)“…Plasma prorenin as an early marker of nephropathy in diabetic (IDDM) adolescents. We studied a group of 50 adolescents, average age 16 years, with diagnosed…”
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Potent ʼnew pressor proteinʼ related to coagulation factor XII is potentiated by inhibition of angiotensin converting enzyme
Published in Journal of hypertension (01-03-1998)“…BACKGROUNDʼNew pressor proteinʼ was observed after tryptic activation of human and rat plasma in vitro, which is done conventionally for prorenin measurements…”
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Potent blood pressure raising effects of activated coagulation factor XII
Published in Canadian journal of physiology and pharmacology (01-12-1997)“…A new pressor protein (NPP) in trypsin-activated human plasma was recently reported, whose blood pressure raising effects in bioassay rats are potentiated 300%…”
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Regulated Systemic Activation of Rat Plasma Prorenin
Published in Hypertension (Dallas, Tex. 1979) (01-07-1987)“…Nephrectomized rats have above-normal plasma prorenin levels, presumably of extrarenal origin, but essentially no renin, suggesting a lack of “convertase” for…”
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Extrarenal Prorenin in Plasma Requires an Activator of Renal Origin
Published in Hypertension (Dallas, Tex. 1979) (01-06-1986)“…Plasma prorenin may be of renal or extrarenal origin, and its conversion to renin may be catalyzed by renal or extrarenal enzymes. We tested the effect of…”
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Plasma Prorenin in Humans and Dogs: Species Differences and Further Evidence of a Systemic Activation Cascade
Published in Hypertension (Dallas, Tex. 1979) (01-05-1983)“…We have studied the dog as a potential model for the human plasma prorenin-renin system. On a regular sodium intake, healthy conscious dogs apparently have a…”
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Can total prorenin in human plasma be determined by current activation methods?
Published in Journal of hypertension (01-12-1986)“…A proper evaluation of the physiological significance of plasma prorenin depends on its accurate determination. However, current activation methods do not…”
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Extrarenal production and activation of human plasma prorenin: the evidence after venous occlusion
Published in Canadian journal of physiology and pharmacology (01-01-1989)“…Venous occlusion of the left arm in consenting men was induced for 10 or 20 min to stimulate local fibrinolytic and other proteases, thereby favouring the…”
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Renin substrate (angiotensinogen) preparations in the determination of prorenin and renin: evidence for extrarenal plasma prorenin and its renal "convertase"
Published in Canadian journal of physiology and pharmacology (01-11-1987)“…Standard methods for determining prorenin-renin concentrations in plasma (PRC) and other tissues require the addition of exogenous renin substrate…”
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P-165: Cardiovascular effects of human ‘new pressor protein’ (NPP) and coagulation β-FXIIa: its potentiation by the ace inhibitor captopril and by 24hr nephrectomy
Published in American journal of hypertension (01-05-2003)“…Enzymic ‘New Pressor Protein’ (NPP), related to coagulation β-FXIIa (β-FXIIa), exerts potent cardiovascular effects when injected into bioassay rats, raising…”
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