Search Results - "Osman, Rihab"
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Near IR responsive targeted integrated lipid polymer nanoconstruct for enhanced magnolol cytotoxicity in breast cancer
Published in Scientific reports (29-05-2020)“…Advances in cancer nanotechnology aim at improving specificity and effectiveness for tumor treatment. Amalgamation of different treatment modalities is…”
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Lecithin-based modified soft agglomerate composite microparticles for inhalable montelukast: Development, tolerability and pharmacodynamic activity
Published in Powder technology (15-01-2020)“…In this work, montelukast (MTK) was incorporated in inhalable soft agglomerates (SA) exhibiting inherent characteristics for deep lung deposition while…”
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3
Polymer-Based Novel Lung Targeted Delivery Systems
Published in Current pharmaceutical design (01-01-2017)“…Due to its unique features, the respiratory tract had received great attention as a promising non-invasive route for drug administration to achieve both local…”
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4
10-Hydroxy Decanoic Acid-Based Vesicles as a Novel Topical Delivery System: Would It Be a Better Platform Than Conventional Oleic Acid Ufasomes for Skin Cancer Treatment?
Published in Pharmaceutics (11-05-2023)“…10-hydroxy decanoic acid (HDA), a naturally derived fatty acid, was used for the preparation of novel fatty acid vesicles for comparison with oleic acid (OA)…”
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5
Lung targeted electrosprayed chitosan nanocomposite microparticles boost the cytotoxic activity of magnolol
Published in Carbohydrate polymer technologies and applications (25-12-2021)“…•PVA ability to improve the spinnability of chitosan (CS) was explored.•Tuned nanoparticles were prepared by electrospraying CS/PVA blended solutions.•The best…”
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Dextran-based Nanocarriers for Delivery of Bioactives
Published in Current pharmaceutical design (01-01-2016)“…Dextran (DX) is a natural polysaccharide produced in the laboratory by fermentation of sucrose under the effect of the enzyme DX sucrase (1,6-α-D-glucan-α-…”
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Polysaccharides-based nanocomplexes for the prolonged delivery of enoxaparin: In-vitro and in-vivo evaluation
Published in International journal of pharmaceutics (30-06-2017)“…[Display omitted] Thromboprophylaxis and anticoagulant therapy face serious medical challenges in terms of how crucial it is to maintain therapeutic activity…”
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Introducing a bionanocomposite (Ultrasound-assisted synthesis of Ag nanoparticles embedded Aloe vera gel) for the treatment of cervical carcinoma
Published in Journal of experimental nanoscience (31-12-2022)“…Regarding applied, facile, green chemical research, a bio-inspired approach is being reported for the sonochemical synthesis of Ag nanoparticles by Aloe vera…”
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A pan-cancer analysis reveals CHD1L as a prognostic and immunological biomarker in several human cancers
Published in Frontiers in molecular biosciences (23-03-2023)“…Several recent studies pointed out that chromodomain-helicase-DNA-binding protein 1-like (CHD1L) is a putative oncogene in many human tumors. However, up to…”
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10
Ex vivo permeation parameters and skin deposition of melatonin-loaded microemulsion for treatment of alopecia
Published in Future journal of pharmaceutical sciences (18-05-2022)“…Background Melatonin (MEL) is a powerful antioxidant molecule with anti-androgenic property. A microemulsion (ME) system loaded with MEL was designed for…”
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Passive targeting and lung tolerability of enoxaparin microspheres for a sustained antithrombotic activity in rats
Published in Drug delivery (01-01-2017)“…Pulmonary bed can retain microparticles (MP) larger than their capillaries' diameter, hence we offer a promising way for lung passive targeting following…”
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12
Exploiting gelatin nanocarriers in the pulmonary delivery of methotrexate for lung cancer therapy
Published in European journal of pharmaceutical sciences (15-05-2019)“…Gelatin has many merits that encourage its use in the pulmonary delivery of anticancer drugs. It is a biodegradable denatured protein which possesses several…”
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Wound healing potential of silver nanoparticles embedded in optimized bio-inspired hybridized chitosan soft and dry hydrogel
Published in Carbohydrate polymers (15-01-2024)“…Interactive wound dressings combining healing and antimicrobial potentials, besides ensuring patient compliance with a recognized wound care service gained…”
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Chitosan-coated nanodiamonds: Mucoadhesive platform for intravesical delivery of doxorubicin
Published in Carbohydrate polymers (01-10-2020)“…[Display omitted] •Chitosan adsorbed on nanodiamonds and reversed their surface charge from negative to positive side.•Further dextran sulphate coating…”
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Towards more efficient inhalable chemotherapy: Fabrication of nanodiamonds-releasing microspheres
Published in International journal of pharmaceutics (15-10-2022)“…[Display omitted] •Nanospray drying minimally impacted the particle size of nanodiamonds.•Powder aerosol deposition suggested excellent potential of reaching…”
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Exploring the potential of oleic acid in nanotechnology-mediated dermal drug delivery: An up-to-date review
Published in Journal of drug delivery science and technology (01-01-2022)“…Oleic acid (OA), the naturally occurring fatty acid, is a multifunctional pharmaceutical excipient with penetration enhancing property for effective skin…”
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Nanodiamonds: Minuscule gems that ferry antineoplastic drugs to resistant tumors
Published in International journal of pharmaceutics (10-03-2019)“…[Display omitted] Remarkable efforts are currently devoted to the area of nanodiamonds (NDs) research due to their superior properties viz: biocompatibility,…”
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Engineering a Novel Water-in-Oil Biocompatible Microemulsion System for the Ocular Delivery of Dexamethasone Sodium Phosphate in the Treatment of Acute Uveitis
Published in International journal of pharmaceutics (25-01-2024)“…Due to their unique characteristics, microemulsions (ME) represent one of the most promising delivery systems which can conquer poor ocular drug…”
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Novel composite fatty acid vesicles-in-Pluronic lecithin organogels for enhanced magnolol delivery in skin cancer treatment
Published in European journal of pharmaceutics and biopharmaceutics (01-08-2024)“…[Display omitted] A novel composite carrier composed of Pluronic lecithin organogels and fatty acid vesicles was used to enhance the stability and facilitate…”
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Polypeptide and glycosaminoglycan polysaccharide as stabilizing polymers in nanocrystals for a safe ocular hypotensive effect
Published in International journal of biological macromolecules (01-11-2020)“…Improved ocular delivery of a poorly soluble anti-glaucoma drug, acetazolamide (ACZ), in a stable nanosuspension (NS) was the main target of the study. The…”
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