Search Results - "Osman, Eman"

Modulatory effect of interleukin-2 loaded chitosan nano sphere on regulatory T cell activity in streptozotocin-induced diabetic mice by Aboelnazar, Salma, Ghoneim, Hossam, Shalaby, Thanaa, Sorour, Sally, Osman, Eman M.

“…•Experimental induction of T1D was performed in male inbred Balb/c mice using strptozotocin.•Free recombinant IL-2 decreased glucose levels in treated…”
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Design and synthesis of methoxyphenyl- and coumarin-based chalcone derivatives as anti-inflammatory agents by inhibition of NO production and down-regulation of NF-κB in LPS-induced RAW264.7 macrophage cells by Emam, Soha H., Sonousi, Amr, Osman, Eman O., Hwang, Dukhyun, Kim, Gun-Do, Hassan, Rasha A.

“…[Display omitted] •Methoxylated and coumarin-based chalcones were designed as anti-inflammatory agents..•2f inhibits NO production in LPS-induced RAW264.7…”
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Design and synthesis of novel quinazolinone-based derivatives as EGFR inhibitors with antitumor activity by Sonousi, Amr, Hassan, Rasha A., Osman, Eman O., Abdou, Amr M., Emam, Soha H.

“…Nineteen new quinazolin-4(3H)-one derivatives 3a-g and 6a-l were designed and synthesised to inhibit EGFR. The antiproliferative activity of the synthesised…”
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The involvement of cytokine gene polymorphism in determining the vulnerability to Blastocystis and Helicobacter pylori co-infection in the Egyptian population by Ibrahim, Asmaa, Kamel, Nancy O., Rageh, Fatma, Elgamal, Rasha, Mansour salama, Bassam, Sakr, Mohamed A., Elhoseeny, Mohamed Mahmoud, Osman, Eman M., Sayed, Samar, Ramadan, Manar Ezzelarab

“…•Blastocystis was detected in 93/314 stool samples (29.6 %); co-infection with H. pylori was verified in 54/93 (58.1 %).•TNF-α −1031 TT and IL-1β +3954 TT…”
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Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer by Halim, Peter A., Hassan, Rasha A., Mohamed, Khaled O., Hassanin, Soha O., Khalil, Mona G., Abdou, Amr M., Osman, Eman O.

“…Novel halogenated phenoxychalcones 2a-f and their corresponding N-acetylpyrazolines 3a-f were synthesised and evaluated for their anticancer activities against…”
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Different panel of toll-like receptors expression during chronic Schistosoma mansoni infection in experimental animals by Saad, Abeer E., Ashour, Dalia S., Osman, Eman M.

“…Many studies have reported the immunomodulatory effect of helminths to avoid the lethal immunopathology. During schistosomiasis, the immune response is…”
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Pyridazine and pyridazinone derivatives: Synthesis and in vitro investigation of their anti‐inflammatory potential in LPS‐induced RAW264.7 macrophages by Osman, Eman O., Khalil, Nadia A., Magdy, Alaa, El‐Dash, Yara

“…New pyridazine and pyridazinone derivatives 3a–g, 4a–f, 6a, and 6b were designed and synthesized. Cell viability of all compounds was established based on the…”
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Genetic polymorphisms of Endoplasmic reticulum amino peptidase 1 (ERAP1) and Interferon lambda 4 (IFN-λ4) in Egyptian patients with type 1 diabetes mellitus by Abo El Nazar, Salma, Ghazy, Amany A, Amer, Ibrahim, Tawfik, Salwa, Nassar, Marwa, Osman, Eman M

“…Different genetic and environmental factors are implicated in type I diabetes (T1DM) pathogenesis. About 50% of the genetic susceptibility for T1DM is related…”
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Design, synthesis, anticancer, and antibacterial evaluation of some quinazolinone‐based derivatives as DHFR inhibitors by Osman, Eman O., Emam, Soha H., Sonousi, Amr, Kandil, Mai M., Abdou, Amr M., Hassan, Rasha A.

“…Two series of quinazolinone derivatives were designed and synthesized as dihydrofolate reductase (DHFR) inhibitors. All compounds were evaluated for their…”
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Anti-IL-8 monoclonal antibodies inhibits the autophagic activity and cancer stem cells maintenance within breast cancer tumor microenvironment by Abou Shousha, Seham, Medhat, Eman, Baheeg, Suzan, Shahine, Yasmine

“…Breast cancer tumor microenvironment (TME) is a promising target for immunotherapy. Autophagy, and cancer stem cells (CSCs) maintenance are essential processes…”
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Coumarin derivatives with potential anticancer and antibacterial activity: Design, synthesis, VEGFR‐2 and DNA gyrase inhibition, and in silico studies by Emam, Soha H., Hassan, Rasha A., Osman, Eman O., Hamed, Mohammed I. A., Abdou, Amr M., Kandil, Mai M., Elbaz, Eman Maher, Mikhail, Demiana S.

“…A series of coumarin derivatives were designed, synthesized, and evaluated for their antiproliferative activity. Compound 3e exhibited significant…”
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Relation between microRNA‐21, transforming growth factor β and response to treatment among chronic hepatitis C patients by Ghazy, Amany A., Osman, Eman M., Rashwan, Eman A., Gaballah, Ahmed H., Mostafa, Hanan, Tawfik, Salwa

“…Background Persistence of hepatitis C virus (HCV) infection and response to antiviral therapy has been shown to be associated with inappropriate levels of…”
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In-vitro Modulation of mTOR-HIF-1α Axis by TLR7/8 Agonist (Resiquimod) in B-Chronic Lymphocytic Leukemia by Hanafy, Rana M., Demian, Soheir R., Abou-Shamaa, Lobna A., Ghallab, O., Osman, Eman M.

“…Targeting toll-like receptors (TLRs), via TLR agonists, has been implicated in the regulation of immunometabolism. B-chronic lymphocytic leukemia (B-CLL)…”
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A snapshot of Plasmodium falciparum malaria drug resistance markers in Sudan: a pilot study by Mohamed, Nouh S, Abdelbagi, Hanadi, Osman, Hussam A, Ahmed, Abdallah E, Yousif, Alaa M, Edris, Yusraa B, Osman, Eman Y, Elsadig, Aahd R, Siddig, Emmanuel E, Mustafa, Madinna, Mohammed, Ammar A, Ali, Yousif, Osman, Maha M, Ali, Mohamed S, Omer, Rihab A, Ahmed, Ayman, Sibley, Carol H

“…Malaria infection is still known to be a worldwide public health problem, especially in tropical and sub-tropical African countries like Sudan. A pilot study…”
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Assessment of vestibulo-spinal reflex function in Multiple sclerosis patients using Computerized Dynamic Posturography by Osman, Eman, Dabbous, Abeir, Shalaby, Nevin, Abousetta, Alaa El-Din, Hosni, Noha

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Fatal Nocardia paucivorans Lower Respiratory Tract Infection in a Tuberculosis Suspect Who Worked as Gold Miner by Nour, Eman Osman Mohamed, Alnour, Tarig M S, Ibrahim, Nuha Yousif, Abdelraheem, Mohamed H, Elhaj, Nihad M A, Elsony, Asma, Mostafa, Galal

“…Nocardiosis is an opportunistic infection that affects both immunocompromised as well as immunocompetent patients. The main infections occur as soft tissue and…”
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Relation between vitamin d level and cyclin-dependent kinase-1 gene expression in egyptian patients with lupus nephritis and their impact on disease activity by Osman, Eman, Abu El Nazar, Salma, Maharem, Dalia, Al-Jebouri, Dhargam, Naga, Iman

“…Introduction: Lupus nephritis (LN) is a common complication of systemic lupus erythematosus. Vitamin D and cycline-dependent kinase-1 (CDK1) have been…”
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Central corneal thickness measurement using ultrasonic pachymeter, optical coherence tomography, and TMS-5 topographer by Binnawi, Kamal, Elzubeir, Hanaa, Osman, Eman, Abdu, Malaz, Abdu, Mustafa

“…AIM: This study aimed to compare the central corneal thickness (CCT) measurements using Optical Coherence Tomography (OCT) and TMS-5 topographer with that…”
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Molecular characterization of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Khartoum, Sudan by Elegail, Asrar, Ibrahim Mohamed, Nuha, Mohamed Nour, Eman, Hoffner, Sven, Haile, Melles

“…Background: The aim of this study was to characterize the drug resistance profile, and the specific lineages of Mycobacterium tuberculosis (MTB) strains…”
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Role Of House Dust Mites In Allergic and Non Allergic Nasal Diseases by Refaat, Maged, Prof, Mansour, Tarek, Prof, Samny, Talaat, Prof, Zaki, Ahmed, Prof, Osman, Eman, Prof, Ezzat, Eman, Dr, Ahmed, Eman, Dr

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