Search Results - "Osman, Eiman A."

Quick Click: The DNA‐Templated Ligation of 3′‐O‐Propargyl‐ and 5′‐Azide‐Modified Strands Is as Rapid as and More Selective than Ligase by Osman, Eiman A., Gadzikwa, Tendai, Gibbs, Julianne M.

“…The copper(I)‐mediated azide–alkyne cycloaddition (CuAAC) of 3′‐propargyl ether and 5′‐azide oligonucleotides is a particularly promising ligation system…”
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Disrupting Protein Expression with Double-Clicked sgRNA–Cas9 Complexes: A Modular Approach to CRISPR Gene Editing by Tijaro-Bulla, Santiago, Osman, Eiman A., St Laurent, Chris D., McCord, Kelli A., Macauley, Matthew S., Gibbs, Julianne M.

“…CRISPR-Cas9 is currently the most versatile technique to perform gene editing in living organisms. In this approach, the Cas9 endonuclease is guided toward its…”
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Non-invasive single cell aptasensing in live cells and animals by Osman, Eiman A, Rynes, Thomas P, Wang, Y. Lucia, Mruk, Karen, McKeague, Maureen

“…We report a genetically encoded aptamer biosensor platform for non-invasive measurement of drug distribution in cells and animals. We combined the high…”
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CRISPR-Click Enables Dual-Gene Editing with Modular Synthetic sgRNAs by Park, Hansol, Osman, Eiman A., Cromwell, Christopher R., St Laurent, Chris D., Liu, Yuning, Kitova, Elena N., Klassen, John S., Hubbard, Basil P., Macauley, Matthew S., Gibbs, Julianne M.

“…Gene-editing systems such as CRISPR-Cas9 readily enable individual gene phenotypes to be studied through loss of function. However, in certain instances, gene…”
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Enhanced mismatch selectivity of T4 DNA ligase far above the probe: Target duplex dissociation temperature by Osman, Eiman A., Alladin‐Mustan, B. Safeenaz, Hales, Sarah C., Matharu, Gunwant K., Gibbs, Julianne M.

“…T4 DNA ligase is a widely used ligase in many applications; yet in single nucleotide polymorphism analysis, it has been found generally lacking owing to its…”
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Cover Feature: Quick Click: The DNA‐Templated Ligation of 3′‐O‐Propargyl‐ and 5′‐Azide‐Modified Strands Is as Rapid as and More Selective than Ligase (ChemBioChem 19/2018) by Osman, Eiman A., Gadzikwa, Tendai, Gibbs, Julianne M.

“…The cover feature picture shows how DNA‐templated, copper‐mediated azide–alkyne cycloaddition (CUAAC) with 3′‐O‐propargyl and 5′‐azide‐terminated…”
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Directed Assembly of Nanoparticle Threshold‐Selector Arrays by Speckbacher, Maximilian, Rinderle, Michael, Kaiser, Waldemar, Osman, Eiman A., Chryssikos, Domenikos, Cattani‐Scholz, Anna, Gibbs, Julianne M., Gagliardi, Alessio, Tornow, Marc

“…The directed assembly of ordered arrays of cubic silver nanoparticles featuring distinct electrical threshold‐switching characteristics is reported. Threshold…”
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