Search Results - "Osipyants, A. I."

Effect of Circulation Parameters on Functional Status of HepaRG Spheroids Cultured in Microbioreactor by Semenova, O. V., Petrov, V. A., Gerasimenko, T. N., Aleksandrova, A. V., Burmistrova, O. A., Khutornenko, A. A., Osipyants, A. I., Poloznikov, A. A., Sakharov, D. A.

“…We studied the relationship between microcirculation parameters and functional status of HepaRG cells in spheroids and chose an optimal regimen within the…”
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Loop-Mediated Isothermal Amplification as a Promising Method for Mass COVID-19 Diagnostics by Makarova, J. A., Fomicheva, K. A., Osipyants, A. I., Shkurnikov, M. Yu, Pokryshchenko, A. A., Tonevitsky, E. A., Vechorko, V. I.

“…Real-time reverse-transcription polymerase chain reaction (RT-PCR) is currently the most popular method for early COVID-19 diagnostics. However, loop-mediated…”
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Enzyme–substrate reporters for evaluation of substrate specificity of HIF prolyl hydroxylase isoforms by Osipyants, A. I., Smirnova, N. A., Khristichenko, A. Yu, Hushpulian, D. M., Nikulin, S. V., Chubar, T. A., Zakhariants, A. A., Tishkov, V. I., Gazaryan, I. G., Poloznikov, A. A.

“…An organism naturally responds to hypoxia via stabilization of hypoxia-inducible factor (HIF). There are three isoforms of HIFα subunits whose stability is…”
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Structural optimization of adaptaquin, a HIF prolyl hydroxylase inhibitor by Poloznikov, A. A., Khristichenko, A. Yu, Smirnova, N. A., Hushpulian, D. M., Gaisina, I. N., Osipyants, A. I., Tishkov, V. I., Gazaryan, I. G.

“…The structural optimization of adaptaquin, viz. , 7-(4-chlorophenyl)[(3-hydroxypyridin-2-yl)amino]methylquinolin-8-ol, a HIF (hypoxia inducible factor) prolyl…”
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Changes in the Level of Circulating hsa-miR-297 and hsa-miR-19b-3p miRNA Are Associated with Generalization of Prostate Cancer by Osip’yants, A. I., Knyazev, E. N., Galatenko, A. V., Nyushko, K. M., Galatenko, V. V., Shkurnikov, M. Yu, Alekseev, B. Ya

“…We performed diagnostic classification of plasma specimens from patients with non-metastatic and metastatic prostate cancer based on pairs of miRNA that have…”
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HIF2 ODD-luciferase reporter: the most sensitive assay for HIF prolyl hydroxylase inhibitors by Smirnova, N. A., Osipyants, A. I., Khristichenko, A. Yu, Hushpulian, D. M., Nikulin, S. V., Chubar, T. A., Zakhariants, A. A., Tishkov, V. I., Gazaryan, I. G., Poloznikov, A. A.

“…Reporters expressing fusion proteins of HIF2 and HIF3 C-terminal oxygen degradable domain (ODD) with the firefly luciferase, HIF2 ODD-luc and HIF3 ODD-luc,…”
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Detection of Potential Metastatic Prostate Cancer Circulating Biomarkers by Comparison of miRNA Profiles in DU145 Cells and Culture Medium by Fomicheva, K. A., Osip’yants, A. I., Knyazev, E. N., Samatov, T. R., Shkurnikov, M. Yu

“…We studied the profile of miRNA secreted into culture medium by DU145 prostate cancer cells and identified a subset of miRNAs characterized by the absence of…”
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Metal Ions as Activators of Hypoxia Inducible Factor by Osipyants, A. I., Smirnova, N. A., Khristichenko, A. Yu, Nikulin, S. V., Zakhariants, A. A., Tishkov, V. I., Gazaryan, I. G., Poloznikov, A. A.

“…Activation of antihypoxic program under the action of a number of transition and heavy metals has been studied using cell-based HIF1 ODD-luc and HRE-luc…”
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Role of ACE2/TMPRSS2 genes regulation by intestinal microRNA isoforms in the COVID-19 pathogenesis by Nersisyan, SA, Shkurnikov, MYu, Osipyants, AI, Vechorko, VI

“…Coronavirus SARS-CoV-2, the cause of the COVID-19 pandemic, enters the cell by binding the cell surface proteins: angiotensin-converting enzyme 2 (ACE2) and…”
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Submerged cultivation of Stephania glabra (Roxb.) Miers cells in different systems: Specific features of growth and accumulation of alkaloid stepharine by Titova, M. V, Reshetnyak, O. V, Osipova, E. A, Osip’yants, A. I, Shumilo, N. A, Oreshnikov, A. V, Nosov, A. M

“…Strains of a Stephania glabra suspension culture grown in flasks and two types of bioreactors (laboratory-scale bubble and pilot-scale stirred reactors) have…”
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Hypoxia enhances transcytosis in intestinal enterocytes by Maltseva, DV, Shkurnikov, MYu, Nersisyan, SA, Nikulin, SV, Kurnosov, AA, Raigorodskaya, MP, Osipyants, AI, Tonevitsky, EA

“…The integrity of the intestinal epithelial cell lining is crucial for the normal intestinal function. As a rule, intestinal inflammation is associated with…”
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Correcting for the barrier effect of protection when using photon buildup factors by Zvantsev, A. A., Ktitrov, S. V., Kudryavtsev, O. G., Mogilenets, N. N., Sakharov, V. K., Bakin, R. I., Krasnoperov, S. N., Osipyants, I. A., Shikin, A. V.

“…Simple, approximate, engineering methods of computation are often used for real-time evaluation of radiation conditions due to sources of photon radiation. The…”
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