Search Results - "Osipov, Sergej N"

3-Trifluoromethyl- and 3-difluoromethyl-thalidomides by Osipov, Sergej N, Tsouker, Pavel, Hennig, Lothar, Burger, Klaus

“…Syntheses of racemic 3-trifluoromethyl- and 3-difluoromethyl-thalidomide starting from 2-( tert-butyloxycarbonylimino)-3,3,3-trifluoropropionate or…”
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Trifluoromethyl-substituted hydantoins, versatile building blocks for rational drug design by Wehner, Volkmar, Stilz, Hans-Ulrich, Osipov, Sergej N, Golubev, Alexander S, Sieler, Joachim, Burger, Klaus

“…Preparatively simple, one-pot syntheses of trifluoromethyl-substituted hydantoins starting from Boc-protected imines of hexafluoroacetone and trifluoropyruvate…”
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A radical pathway to α-difluoromethylene containing prolines and α-aminoadipic acids by Osipov, Sergej N, Burger, Klaus

“…A new approach to the synthesis of α-difluoromethylene containing prolinates and α-aminoadipates has been developed. The method is based on intra- and…”
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Synthesis of highly fluorinated dipeptide building blocks by Koksch, Beate, Mütze, Kerstin, Osipov, Sergej N, Golubev, Alexander S, Burger, Klaus

“…A new approach to the synthesis of dipeptides containing up to three trifluoromethyl groups has been developed. The method is based on a [4+1]-cycloaddition…”
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Hexafluoroacetone as protecting and activating reagent: reactions of hexafluoroacetone with α-keto acids by Spengler, Jan, Osipov, Sergej N., Heistracher, Elisabeth, Haas, Alois, Burger, Klaus

“…Graphic Hexafluoroacetone and α-keto acids react to give 5,5-bis(trifluoromethyl) substituted 2(5H)-furanones and/or…”
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Synthesis of trifluoromethyl-containing depsipeptides via OH insertion of rhodium carbenoid into the carboxylic group of N-protected α-amino acids by Vorob’eva, Daria V., Titanyuk, Igor D., Beletskaya, Irina P., Osipov, Sergej N.

“…A new approach to trifluoromethyl-depsipeptides involving the formation of a COO–CH(CF 3)CO link by a metal carbene insertion reaction into the COOH group of…”
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Unexpected Ring Transformations on Functionalization of 2-(ω-Alken-1-yl)-3,3,3-trifluoroalanine Derivatives by Burger, Klaus, Mütze, Kerstin, Osipov, Sergej N., Tsouker, Pavel, Schier, Annette

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