Search Results - "Osinski, Carla"
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A Glycopeptide in Complex with MHC Class I Uses the GalNAc Residue as an Anchor
Published in Proceedings of the National Academy of Sciences - PNAS (09-12-2003)“…Peptides bind MHC class I molecules by anchoring hydrophobic side chains into pockets in the peptide binding groove. Here, we report an immunogenic (in vitro…”
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MUC1 cross-reactive Galα(l,3)Gal antibodies in humans switch immune responses from cellular to humoral
Published in Nature medicine (01-03-1998)“…Successful tumor immunotherapy with peptides requires the induction of cytotoxic T lymphocytes (CTLs) rather than antibodies. Mice immunized with mannan…”
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Definition of MHC-restricted CTL epitopes from non-variable number of tandem repeat sequence of MUC1
Published in Vaccine (03-04-2000)“…Mucin1 (MUC1) is expressed ubiquitously on breast cancer cells and is a potential target for the generation of cytotoxic T cells for vaccination against breast…”
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Oxidised mannan antigen conjugates preferentially stimulate T1 type immune responses
Published in Veterinary immunology and immunopathology (15-05-1998)“…It is desirable to be able to produce either T1 or T2 responses and we have found that, in mice, mannose - coupled antigens stimulated T2 type responses…”
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