Search Results - "Osier, Michael"

Comparison of Short-Read Sequence Aligners Indicates Strengths and Weaknesses for Biologists to Consider by Musich, Ryan, Cadle-Davidson, Lance, Osier, Michael V

“…Aligning short-read sequences is the foundational step to most genomic and transcriptomic analyses, but not all tools perform equally, and choosing among the…”
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The epiphytic microbiota of sour rot-affected grapes differs minimally from that of healthy grapes, indicating causal organisms are already present on healthy berries by Hall, Megan E, O'Bryon, Isabelle, Wilcox, Wayne F, Osier, Michael V, Cadle-Davidson, Lance

“…Sour rot is a disease complex produced by an interaction between grape berries and various species of yeast and acetic acid bacteria in the presence of…”
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Transcriptomic Profiling of Acute Cold Stress-Induced Disease Resistance (SIDR) Genes and Pathways in the Grapevine Powdery Mildew Pathosystem by Weldon, William A, Palumbo, Cal D, Kovaleski, Alisson P, Tancos, Kiersten, Gadoury, David M, Osier, Michael V, Cadle-Davidson, Lance

“…Temperatures from 2 to 8°C transiently induce quantitative resistance to powdery mildew in several host species (cold stress-induced disease resistance…”
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Kidney Tumor Biomarkers Revealed by Simultaneous Multiple Matrix Metabolomics Analysis by GANTI, Sheila, TAYLOR, Sandra L, ABU ABOUD, Omran, YANG, Joy, EVANS, Christopher, OSIER, Michael V, ALEXANDER, Danny C, KIM, Kyoungmi, WEISS, Robert H

“…Metabolomics is increasingly being used in cancer biology for biomarker discovery and identification of potential novel therapeutic targets. However, a…”
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Global Proteomic Profiling of Salmonella Infection by a Giant Phage by Weintraub, Susan T, Mohd Redzuan, Nurul Humaira, Barton, Melissa K, Md Amin, Nur Amira, Desmond, Maxim I, Adams, Lily E, Ali, Bazla, Pardo, Sammy, Molleur, Dana, Wu, Weimin, Newcomb, William W, Osier, Michael V, Black, Lindsay W, Steven, Alasdair C, Thomas, Julie A

“…The 240-kb phage SPN3US genome encodes 264 gene products, many of which are functionally uncharacterized. We have previously used mass spectrometry to define…”
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Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer by Kim, Kyoungmi, Taylor, Sandra L, Ganti, Sheila, Guo, Lining, Osier, Michael V, Weiss, Robert H

“…Kidney cancer is the seventh most common cancer in the Western world, its incidence is increasing, and it is frequently metastatic at presentation, at which…”
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Whole-Genome Sequence, Assembly and Annotation of an Invasive Plant, Lonicera maackii (Amur Honeysuckle) by Kesel, Erin, Hudson, André O, Osier, Michael V

“…The invasive species (Amur Honeysuckle) is an increasing problem sweeping from the eastern United States toward the west, impacting normal forest development…”
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Identification of Essential Genes in the Salmonella Phage SPN3US Reveals Novel Insights into Giant Phage Head Structure and Assembly by Thomas, Julie A, Benítez Quintana, Andrea Denisse, Bosch, Martine A, Coll De Peña, Adriana, Aguilera, Elizabeth, Coulibaly, Assitan, Wu, Weimin, Osier, Michael V, Hudson, André O, Weintraub, Susan T, Black, Lindsay W

“…Giant tailed bacterial viruses, or phages, such as Pseudomonas aeruginosa phage ϕKZ, have long genomes packaged into large, atypical virions. Many aspects of…”
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Pedigree Go Fish by Osier, Michael V

“…A card game based upon the classic game Go Fish is presented for active practicing of segregation analysis, the determination of the most likely method of…”
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To Be or Not To Be T4: Evidence of a Complex Evolutionary Pathway of Head Structure and Assembly in Giant Salmonella Virus SPN3US by Ali, Bazla, Desmond, Maxim I, Mallory, Sara A, Benítez, Andrea D, Buckley, Larry J, Weintraub, Susan T, Osier, Michael V, Black, Lindsay W, Thomas, Julie A

“…Giant phage SPN3US has a 240-kb dsDNA genome and a large complex virion composed of many proteins for which the functions of most are undefined. We recently…”
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A board game for undergraduate genetics vocabulary and concept review: the pathway shuffle by Osier, Michael V

“…A board game for the review of fundamental genetics concepts is presented. The game is easily prepared and dropped into a classroom setting. Printable…”
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Evidence of Positive Selection on a Class I ADH Locus by Han, Yi, Gu, Sheng, Oota, Hiroki, Osier, Michael V., Pakstis, Andrew J., Speed, William C., Kidd, Judith R., Kidd, Kenneth K.

“…The alcohol dehydrogenase (ADH) family of enzymes catalyzes the reversible oxidation of alcohol to acetaldehyde. Seven ADH genes exist in a segment of ∼370 kb…”
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A Global Perspective on Genetic Variation at the ADH Genes Reveals Unusual Patterns of Linkage Disequilibrium and Diversity by Osier, Michael V., Pakstis, Andrew J., Soodyall, Himla, Comas, David, Goldman, David, Odunsi, Adekunle, Okonofua, Friday, Parnas, Josef, Schulz, Leslie O., Bertranpetit, Jaume, Bonne-Tamir, Batsheva, Lu, Ru-Band, Kidd, Judith R., Kidd, Kenneth K.

“…Variants of different Class I alcohol dehydrogenase (ADH) genes have been shown to be associated with an effect that is protective against alcoholism. Previous…”
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Genes and biochemical pathways in human skeletal muscle affecting resting energy expenditure and fuel partitioning by XUXIA WU, PATKI, Amit, GARVEY, W. Timothy, LARA-CASTRO, Cristina, XIANGQIN CUI, KUI ZHANG, WALTON, R. Grace, OSIER, Michael V, GADBURY, Gary L, ALLISON, David B, MARTIN, Mitchell

“…Genes influencing resting energy expenditure (REE) and respiratory quotient (RQ) represent candidate genes for obesity and the metabolic syndrome because of…”
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Allelic variation at alcohol metabolism genes (ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population by MULLIGAN, Connie J, ROBIN, Robert W, OSIER, Michael V, SAMBUUGHIN, Nyamkhishig, GOLDFARB, Lev G, KITTLES, Rick A, HESSELBROCK, Diane, GOLDMAN, David, LONG, Jeffrey C

“…Enzymes encoded by two gene families, alcohol dehydrogenase ( ADH) and aldehyde dehydrogenase ( ALDH), mediate alcohol metabolism in humans. Allelic variants…”
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The effect of insulin on expression of genes and biochemical pathways in human skeletal muscle by Wu, Xuxia, Wang, Jelai, Cui, Xiangqin, Maianu, Lidia, Rhees, Brian, Rosinski, James, So, W Venus, Willi, Steven M, Osier, Michael V, Hill, Helliner S, Page, Grier P, Allison, David B, Martin, Mitchell, Garvey, W Timothy

“…To study the insulin effects on gene expression in skeletal muscle, muscle biopsies were obtained from 20 insulin sensitive individuals before and after…”
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Handling multiple testing while interpreting microarrays with the Gene Ontology Database by Osier, Michael V, Zhao, Hongyu, Cheung, Kei-Hoi

“…The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using…”
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Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism by Osier, Michael, Pakstis, Andrew J., Kidd, Judith R., Lee, Jia-Fu, Yin, Shih-Jiun, Ko, Huei-Chen, Edenberg, Howard J., Lu, Ru-Band, Kidd, Kenneth K.

“…Two of the three class I alcohol dehydrogenase (ADH) genes ( ADH2 and ADH3) encode known functional variants that act on alcohol with different efficiencies…”
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ALFRED: An allele frequency database for anthropology by Osier, Michael V., Cheung, Kei-Hoi, Kidd, Judith R., Pakstis, Andrew J., Miller, Perry L., Kidd, Kenneth K.

“…The deluge of data from the human genome project (HGP) presents new opportunities for molecular anthropologists to study human variation through the promise of…”
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A Proline-Threonine Substitution in Codon 351 of ADH1C Is Common in Native Americans by Osier, Michael V., Pakstis, Andrew J., Goldman, David, Edenberg, Howard J., Kidd, Judith R., Kidd, Kenneth K.

“…Background The alcohol dehydrogenase (ADH) genes have been repeatedly associated with protection against alcoholism. Until now, only four protein coding…”
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