Search Results - "Osiecka, R"
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Induction of chromosome aberrations in cultured human lymphocytes treated with ethoxyquin
Published in Mutation research (09-12-2003)“…The chromosomal aberration test was employed to investigate the effect in vitro of a known antioxidant and food preservative, ethoxyquin (EQ,…”
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Analysis of aclarubicin-induced cell death in human fibroblasts
Published in Cell biology international (01-09-2007)“…In the present study we investigated the mode of cell death induced by aclarubicin (ACL) in trisomic (BB) and normal (S-2) human fibroblasts. Cells were…”
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Comparison between the genotoxicity of cis-Pt(II) complex of 3-aminoflavone and cis-DDP in lymphocytes evaluated by the comet assay
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-01-2005)“…cis-bis(3-aminoflavone)dichloroplatinum(II) [cis-Pt(II) complex of 3-aminoflavone] is an analog of cis-DDP characterized by low cytotoxicity and anticancer…”
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Vicia faba chromosomal aberration assay
Published in Mutation research (16-10-1994)“…A collaborative study involving laboratories in six countries was initiated under the sponsorship of the International Programme on Chemical Safety (IPCS) to…”
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Growth-retarding effect of 2-aminoindan-2-phosphonic acid on Spirodela punctata
Published in Journal of plant growth regulation (01-09-1998)“…2-Aminoindan-2-phosphonic acid (AIP) retarded the growth of duckweed, Spirodela punctata, and increased its dry mass. The accumulation of starch was observed…”
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Flavonoid compounds: a review of anticancer properties and interactions with cis-diamminedichloroplatinum(II)
Published in Drug development research (01-12-2004)“…Flavonoid compounds, especially quercetin and genistein, have antitumor activity. These compounds are cytotoxic to cancer cells but have no or insignificant…”
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Induction of apoptosis and necrosis in A549 cells by the cis-Pt(II) complex of 3-aminoflavone in comparison with cis-DDP
Published in Mutation research (12-09-2004)“…Non-small cell lung cancer (NSCLC) includes a group of tumors that respond poorly to drugs. cis-Diamminedichloroplatinum(II) ( cis-DDP) toxicity still remains…”
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Electrochemical genosensing of the interaction between the potential chemotherapeutic agent, cis-bis(3-aminoflavone)dichloroplatinum(II) and DNA in comparison with cis-DDP
Published in Journal of pharmaceutical and biomedical analysis (15-07-2005)“…The interaction of cis-diamminedichloroplatinum(II) ( cis-DDP) and the potential novel chemotherapeutic agent, cis-bis(3-aminoflavone)dichloroplatinum(II) (…”
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The effect of herbicide "Chwastox płynny 30" on the cell cycle parameters in root meristem of Vicia faba L. subsp. minor
Published in Folia histochemica et cytobiologica (1991)“…The duration of the cell cycle and its phases after the treatment with herbicide "Chwastox płynny 30" was calculated using 3H-thymidine labelling method…”
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Synthesis, spectroscopy and antiproliferative activity of cis- and trans-platinum(II) complexes with diethyl (pyridin-4-ylmethyl)phosphate. X-ray crystal structure of trans-Pt(II) complex
Published in Journal of inorganic biochemistry (01-10-2005)“…Preparations of cis- and trans-platinum(II) complexes of diethyl (pyridin-4-ylmethyl)phosphate (4-pmOpe) have been described. These complexes were identified…”
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Genotoxicity of novel trans-platinum(II) complex with diethyl (pyridin-4-ylmethyl)phosphate in human non-small cell lung cancer cells A549
Published in Chemico-biological interactions (30-06-2007)“…The dynamic development of metal-containing anticancer drugs has started since the discovery of cis-diamminedichloroplatinum(II). For many years it was…”
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Induction of apoptosis and necrosis in lymphocytes by the cis-Pt(II) complex of 3-aminoflavone in comparison with cis-DDP
Published in Mutation research (14-03-2004)“…cis-Diamminedichloroplatinum(II) ( cis-DDP) is one of the most widely administrated antitumor drugs. However, the use of cis-DDP is severely limited because of…”
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13
Clastogenic and mitodepressive effects of the insecticide dichlorvos on root meristems of Vicia faba
Published in Journal of applied genetics (2007)“…Plant bioassays are an important and integral part of the test battery used in detecting genotoxic/carcinogenic contamination in the environment. Highly…”
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Relation between nuclear DNA content and rate of cell growth during interphase in four species of Angiospermae
Published in Acta Societatis Botanicorum Poloniae (1978)“…Among four species of Angiospermae with known nuclear DNA content (Cucurbita pepo - 2.6 pg, Helianthus annuus - 12.0 pg, Vicia faba — 38.0 pg, and Tulipa…”
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Evaluation of the genotoxicity of cis-bis(3-aminoflavone)dichloroplatinum(II) in comparison with cis-DDP
Published in Mutation research (14-03-2004)“…Short-term tests that detect genetic damage have provided information needed for evaluating carcinogenic risks of chemicals to man. The mutagenicity of…”
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Novel Analogues of 5-Fluorouracil - Synthesis, X-ray Crystallography, and Cytotoxic Effects in Normal Human Peripheral Blood Lymphocytes and Colon Adenocarcinoma HT 29
Published in European Journal of Inorganic Chemistry (01-08-2005)“…The aim of many studies is to discover new chemicals as potential antitumor agents. We have prepared novel analogues of 5‐fluorouracil (5‐Fu):…”
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Enhanced P53 and BAX gene expression and apoptosis in A549 cells by cis-Pt(II) complex of 3-aminoflavone in comparison with cis-DDP
Published in Investigational new drugs (01-08-2005)“…Lung cancer remains one of the most common causes of cancer-related death worldwide. Approximately 80% is histologically non-small cell lung carcinoma (NSCLC)…”
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Evaluation of P53 and BAX gene expression and induction of apoptosis and necrosis by the cis-Pt(II) complex of 3-aminoflavone in comparison with cis-diamminedichloroplatinum(II) ( cis-DDP) in human lymphocytes
Published in Mutation research (30-04-2006)“…Currently cis-diamminedichloroplatinum(II) ( cis-DDP) is one of the most commonly applied compounds in chemotherapy of many types of cancer. However, a…”
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Comparison Between the Genotoxicity of cis-Pt(II) Complex of 3-Aminoflavone and cis-DDP in Lymphocytes Evaluated by the Comet Assay
Published in Drug and chemical toxicology (New York, N.Y. 1978) (2005)“…cis-bis(3-aminoflavone)dichloroplatinum(II) [cis-Pt(II) complex of 3-aminoflavone] is an analog of cis-DDP characterized by low cytotoxicity and anticancer…”
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