Search Results - "Oshinowo, Oluwamayokun"

Single-pericyte nanomechanics measured by contraction cytometry by Islam, Md. Mydul, Gaska, Ignas, Oshinowo, Oluwamayokun, Otumala, Adiya, Shekhar, Shashank, Au Yong, Nicholas, Myers, David R.

“…Pericytes line the microvasculature throughout the body and play a key role in regulating blood flow by constricting and dilating vessels. However, the…”
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Resolving the missing link between single platelet force and clot contractile force by Sun, Yueyi, Oshinowo, Oluwamayokun, Myers, David R., Lam, Wilbur A., Alexeev, Alexander

“…Blood clot contraction plays an important role in wound healing and hemostasis. Although clot contraction is known to be driven by platelets, how single…”
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Getting a good view: in vitro imaging of platelets under flow by Oshinowo, Oluwamayokun, Lambert, Tamara, Sakurai, Yumiko, Copeland, Renee, Hansen, Caroline E., Lam, Wilbur A., Myers, David R.

“…As the anucleate cells responsible for hemostasis and thrombosis, platelets are exposed to a myriad of biophysical and biochemical stimuli within vasculature…”
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Iclots: Open-Source, Artificial Intelligence-Enabled Software for Analyses of Microscopy-Based Data in Hematology by Fay, Meredith E., Oshinowo, Oluwamayokun, Lam, Wilbur A.

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Why platelet mechanotransduction matters for hemostasis and thrombosis by Oshinowo, Oluwamayokun, Azer, Sally S., Lin, Jessica, Lam, Wilbur A.

“…Mechanotransduction is the ability of cells to “feel” or sense their mechanical microenvironment and integrate and convert these physical stimuli into adaptive…”
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Effect of Epitope Specific Antibodies on Single Platelet Physiology with Implications for Immune Thrombocytopenia Purpura by Shaver, Nina, Oshinowo, Oluwamayokun, Fay, Meredith E., Myers, David R., Lam, Wilbur A

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Quantitative Platelet Adhesion and Platelet Geometry-Sensing Assays for Evaluating Mild Bleeding Disorders by Azer, Sally, Oshinowo, Oluwamayokun, Fay, Meredith E., Sakurai, Yumiko, Brown, Megan C., Bennett, Carolyn, Meeks, Shannon L., Lam, Wilbur A.

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STEM Education for Children with Sickle Cell Disease: Unique Educational Outreach Program Taught By Near-Peer Undergraduate Students by Hardy, Elaissa L., Williams, Brenda, Harden, Christopher, Oshinowo, Oluwamayokun, Copeland, Renee, Gee, Beatrice, Lam, Wilbur A.

“…One fifth of school aged children in the US have a chronic medical illness and represent an underserved and educationally disadvantaged population. In…”
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Introducing a Novel Biophysical Platelet Function Panel to Investigate Disorders of Primary Hemostasis and Bleeding of Unknown Cause by Azer, Sally, Oshinowo, Oluwamayokun, Fay, Meredith E., Sakurai, Yumiko, Qiu, Yongzhi, Bennett, Carolyn M., Meeks, Shannon, Brown, Megan C., Myers, David R., Lam, Wilbur A.

“…A subset of patients with chronic bleeding remain undiagnosed even after extensive diagnostic evaluation are labeled as “bleeding of unknown cause” (BUC). The…”
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Platelet Contraction Force As a Biophysical Biomarker for Bleeding Risk in Patients with Immune Thrombocytopenia by Oshinowo, Oluwamayokun T., Copeland, Renee, Bennett, Carolyn M., Lam, Wilbur A, Myers, David R.

“…Background: Immune Thrombocytopenia Purpura (ITP) is defined by a low platelet count in the absence of any known causes and affects over 4,000 US children and…”
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Opportunities and considerations for studying liver disease with microphysiological systems on a chip by Otumala, Adiya E, Hellen, Dominick J, Luna, C Alessandra, Delgado, Priscilla, Dissanayaka, Anjana, Ugwumadu, Chidozie, Oshinowo, Oluwamayokun, Islam, Md Mydul, Shen, Luyao, Karpen, Saul J, Myers, David R

“…Advances in microsystem engineering have enabled the development of highly controlled models of the liver that better recapitulate the unique biological…”
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Platelet heterogeneity enhances blood clot volumetric contraction: An example of asynchrono-mechanical amplification by Sun, Yueyi, Myers, David R., Nikolov, Svetoslav V., Oshinowo, Oluwamayokun, Baek, John, Bowie, Samuel M., Lambert, Tamara P., Woods, Eric, Sakurai, Yumiko, Lam, Wilbur A., Alexeev, Alexander

“…Physiological processes such as blood clotting and wound healing as well as pathologies such as fibroses and musculoskeletal contractures, all involve…”
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HTRS2023.O6A.1 Leveraging quantitative platelet adhesion and platelet geometry-sensing assays to evaluate platelet function in type 1 von Willebrand disease by Azer, Sally, Oshinowo, Oluwamayokun, Sakurai, Yumiko, Brown, Megan C., Fay, Meredith, Meeks, Shannon, Lam, Wilbur

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Increased Platelet Force Is Associated with Decreased Bleeding Severity in Pediatric Immune Thrombocytopenia by Oshinowo, Oluwamayokun T., Copeland, Renee, Caruso, Christina, Fay, Meredith E., Leong, Traci, Bennett, Carolyn M., Lam, Wilbur A., Myers, David R.

“…Background: Immune Thrombocytopenia Purpura (ITP) can result in severely low platelet counts and while most of the 4,000 new cases of pediatric ITP diagnosed…”
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Building the foundation of health‐related knowledge via near‐peer education for children with sickle cell disease by Hardy, Elaissa L. Trybus, Williams, Brenda, Harden, Christopher, Oshinowo, Oluwamayokun, Copeland, Renee, Carden, Marcus A., Gee, Beatrice E., Lam, Wilbur A.

“…Health education for children with chronic illnesses (i.e., sickle cell disease [SCD]) has focused on educating adult caregivers with minimal consideration to…”
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Platelet Contraction Cytometry: A Biophysical, High-Throughput Research-Enabling and Diagnostic Platform by Oshinowo, Oluwamayokun T., Lam, Aaron W., Brainard, Benjamin, Bennett, Carolyn M., Lam, Wilbur A., Myers, David R.

“…Background : During blood clot formation, platelets undergo muscle-like contraction with nascent fibrin polymers to mechanically stabilize the clot and stem…”
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A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species by Copeland, Renee, Oshinowo, Oluwamayokun T., Sakurai, Yumiko, Fay, Meredith Ellen, Petrich, Brian G., Brainard, Benjamin, Lam, Wilbur A, Myers, David R.

“…Background: Animal models of hemostasis play a crucial role in understanding hemostasis and developing novel therapeutic treatments. Hemostasis is a mechanical…”
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iCLOTS: open-source, artificial intelligence-enabled software for analyses of blood cells in microfluidic and microscopy-based assays by Fay, Meredith E., Oshinowo, Oluwamayokun, Iffrig, Elizabeth, Fibben, Kirby S., Caruso, Christina, Hansen, Scott, Musick, Jamie O., Valdez, José M., Azer, Sally S., Mannino, Robert G., Choi, Hyoann, Zhang, Dan Y., Williams, Evelyn K., Evans, Erica N., Kanne, Celeste K., Kemp, Melissa L., Sheehan, Vivien A., Carden, Marcus A., Bennett, Carolyn M., Wood, David K., Lam, Wilbur A.

“…While microscopy-based cellular assays, including microfluidics, have significantly advanced over the last several decades, there has not been concurrent…”
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Significant differences in single-platelet biophysics exist across species but attenuate during clot formation by Oshinowo, Oluwamayokun, Copeland, Renee, Sakurai, Yumiko, Fay, Meredith E., Petrich, Brian G., Leong, Traci, Brainard, Benjamin, Lam, Wilbur A.

“…•Human, canine, ovine, and porcine platelets exhibit disparate biophysical signatures, whereas human and murine platelets are similar.•Multiple biophysical…”
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Investigating the dissemination of STEM content on social media with computational tools by Oshinowo, Oluwamayokun, Delgado, Priscila, Fay, Meredith, Luna, C. Alessandra, Dissanayaka, Anjana, Jeltuhin, Rebecca, Myers, David R

“…Social media platforms can quickly disseminate STEM content to diverse audiences, but their operation can be mysterious. We used open-source machine learning…”
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