Search Results - "Oshima, Robert"

Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors by Islas, Jose Francisco, Liu, Yu, Weng, Kuo-Chan, Robertson, Matthew J, Zhang, Shuxing, Prejusa, Allan, Harger, John, Tikhomirova, Dariya, Chopra, Mani, Iyer, Dinakar, Mercola, Mark, Oshima, Robert G, Willerson, James T, Potaman, Vladimir N, Schwartz, Robert J

“…Unique insights for the reprograming of cell lineages have come from embryonic development in the ascidian Ciona , which is dependent upon the transcription…”
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Intermediate filaments: A historical perspective by Oshima, Robert G.

“…Intracellular protein filaments intermediate in size between actin microfilaments and microtubules are composed of a surprising variety of tissue specific…”
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Cell Cycle-Dependent Variation of a CD133 Epitope in Human Embryonic Stem Cell, Colon Cancer, and Melanoma Cell Lines by JAKSCH, Marie, MUNERA, Jorge, BAJPAI, Ruchi, TERSKIKH, Alexey, OSHIMA, Robert G

“…CD133 (Prominin1) is a pentaspan transmembrane glycoprotein expressed in several stem cell populations and cancers. Reactivity with an antibody (AC133) to a…”
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Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis by Wei, Guo, Srinivasan, Ruchika, Cantemir-Stone, Carmen Z., Sharma, Sudarshana M., Santhanam, Ramasamy, Weinstein, Michael, Muthusamy, Natarajan, Man, Albert K., Oshima, Robert G., Leone, Gustavo, Ostrowski, Michael C.

“…The ras/Raf/Mek/Erk pathway plays a central role in coordinating endothelial cell activities during angiogenesis. Transcription factors Ets1 and Ets2 are…”
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Postnatal Tissue-specific Disruption of Transcription Factor FoxN1 Triggers Acute Thymic Atrophy by Cheng, Lili, Guo, Jianfei, Sun, Liguang, Fu, Jian, Barnes, Peter F., Metzger, Daniel, Chambon, Pierre, Oshima, Robert G., Amagai, Takashi, Su, Dong-Ming

“…The transcription factor FoxN1 is essential for differentiation of thymic epithelial cell (TEC) progenitors during thymic organogenesis. However, limited…”
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ROCK1 Inhibition Promotes the Self‐Renewal of a Novel Mouse Mammary Cancer Stem Cell by Castro, David J., Maurer, Jochen, Hebbard, Lionel, Oshima, Robert G.

“…The differentiation of stem‐like tumor cells may contribute to the cellular heterogeneity of breast cancers. We report the propagation of highly enriched mouse…”
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Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo by HEBBARD, Lionel W, MAURER, Jochen, MILLER, Amber, LESPERANCE, Jacqueline, HASSELL, John, OSHIMA, Robert G, TERSKIKH, Alexey V

“…Maternal embryonic leucine zipper kinase (MELK) is expressed in several developing tissues, in the adult germ line, and in adult neural progenitors. MELK…”
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T-cadherin Supports Angiogenesis and Adiponectin Association with the Vasculature in a Mouse Mammary Tumor Model by HEBBARD, Lionel W, GARLATTI, Michèle, YOUNG, Lawrence J. T, CARDIFF, Robert D, OSHIMA, Robert G, RANSCHT, Barbara

“…T-cadherin delineates endothelial, myoepithelial, and ductal epithelial cells in the normal mouse mammary gland, and becomes progressively restricted to the…”
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Complementation of placental defects and embryonic lethality by trophoblast-specific lentiviral gene transfer by Ikawa, Masahito, Okada, Yuka, Ueshin, Yuko, Isotani, Ayako, Saito-Fujita, Tomoko, Nakashima, Hisako, Kimura, Kazushi, Mizoguchi, Akira, Oh-hora, Masatsugu, Mori, Yoshiko, Ogata, Masato, Oshima, Robert G, Okabe, Masaru

“…Placental dysfunction underlies many complications during pregnancy, and better understanding of gene function during placentation could have considerable…”
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Transcription Factor Ets1, but Not the Closely Related Factor Ets2, Inhibits Antibody-Secreting Cell Differentiation by John, Shinu, Russell, Lisa, Chin, Shu Shien, Luo, Wei, Oshima, Robert, Garrett-Sinha, Lee Ann

“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Ets2 is required for trophoblast stem cell self-renewal by Wen, Fang, Tynan, John A., Cecena, Grace, Williams, Roy, Múnera, Jorge, Mavrothalassitis, George, Oshima, Robert G.

“…The Ets2 transcription factor is essential for the development of the mouse placenta and for generating signals for embryonic mesoderm and axis formation…”
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Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline by Elson, Daniel J., Nguyen, Bach D., Bernales, Sebastian, Chakravarty, Sarvajit, Jang, Hyo Sang, Korjeff, Nicholas A., Zhang, Yi, Wilferd, Sierra F., Castro, David J., Plaisier, Christopher L., Finlay, Darren, Oshima, Robert G., Kolluri, Siva K.

“…Triple-negative breast cancer (TNBC) remains a disease with a paucity of targeted treatment opportunities. The aryl hydrocarbon receptor (AhR) is a…”
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Contrasting expression of keratins in mouse and human embryonic stem cells by Maurer, Jochen, Nelson, Brandon, Ceceña, Grace, Bajpai, Ruchi, Mercola, Mark, Terskikh, Alexey, Oshima, Robert G

“…RNA expression data reveals that human embryonic stem (hES) cells differ from mouse ES (mES) cells in the expression of RNAs for keratin intermediate filament…”
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ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human breast cancer by Strietz, Juliane, Stepputtis, Stella S, Preca, Bogdan-Tiberius, Vannier, Corinne, Kim, Mihee M, Castro, David J, Au, Qingyan, Boerries, Melanie, Busch, Hauke, Aza-Blanc, Pedro, Heynen-Genel, Susanne, Bronsert, Peter, Kuster, Bernhard, Stickeler, Elmar, Brabletz, Thomas, Oshima, Robert G, Maurer, Jochen

“…Cancers are heterogeneous by nature. While traditional oncology screens commonly use a single endpoint of cell viability, altering the phenotype of…”
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Ets2 Regulates Colonic Stem Cells and Sensitivity to Tumorigenesis by Múnera, Jorge, Ceceña, Grace, Jedlicka, Paul, Wankell, Miriam, Oshima, Robert G.

“…Ets2 has both tumor repressive and supportive functions for different types of cancer. We have investigated the role of Ets2 within intestinal epithelial cells…”
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Caspase Cleavage of Keratin 18 and Reorganization of Intermediate Filaments during Epithelial Cell Apoptosis by Caulín, Carlos, Salvesen, Guy S., Oshima, Robert G.

“…Keratins 8 (K8) and 18 (K18) are major components of intermediate filaments (IFs) of simple epithelial cells and tumors derived from such cells. Structural…”
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Changes in the Expression of Many Ets Family Transcription Factors and of Potential Target Genes in Normal Mammary Tissue and Tumors by Galang, Christina K., Muller, William J., Foos, Gabriele, Oshima, Robert G., Hauser, Craig A.

“…Interfering with Ets transcription factor function reverses multiple aspects of the transformed phenotype of mouse or human tumor cells. However, the unknown…”
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Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer by MEI LIU, HOWES, Amy, LESPERANCE, Jacqueline, STALLCUP, William B, HAUSER, Craig A, KADOYA, Kuniko, OSHIMA, Robert G, ABRAHAM, Robert T

“…The ErbB2 (Neu) receptor tyrosine kinase is frequently overexpressed in human breast cancers, and this phenotype correlates with a poor clinical prognosis. We…”
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Oxidized analogs of Di(1 H -indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity by Sanchez, Marisa, Xia, Zebin, Rico-Bautista, Elizabeth, Cao, Xihua, Cuddy, Michael, Castro, David J, Correa, Ricardo G, Chen, Liqun, Yu, Jinghua, Bobkov, Andrey, Ruvolo, Vivian, Andreeff, Michael, Oshima, Robert G, Matsuzawa, Shu-Ichi, Reed, John C, Zhang, Xiao-Kun, Hansel, Donna, Wolf, Dieter A, Dawson, Marcia I

“…Di(1 -indol-3-yl)(4-trifluoromethylphenyl)methane (DIM-Ph-4-CF ) is an analog of orphan nuclear receptor 4A1 (NR4A1) ligand cytosporone B. We have synthesized…”
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Placenta-specific gene activation and inactivation using integrase-defective lentiviral vectors with the Cre/LoxP system by Morioka, Yuka, Isotani, Ayako, Oshima, Robert G., Okabe, Masaru, Ikawa, Masahito

“…Transgenic and knockout studies have advanced our understanding of the genetic control of embryonic development over the past decades. However, interpretation…”
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