Search Results - "Oshima, Kenzi"
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Characterization of human Ccser2 as a protein tracking the plus-ends of microtubules
Published in BMC research notes (08-09-2023)“…Microtubules, which are closely related to cell proliferation, have been the promising therapeutic target of cancer. Therefore, it is necessary to understand…”
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Hyaluronan degradation and release of a hyaluronan-aggrecan complex from perineuronal nets in the aged mouse brain
Published in Biochimica et biophysica acta. General subjects (01-02-2021)“…Perineuronal nets (PNNs) are insoluble aggregates of extracellular matrix molecules in the brain that consist of hyaluronan (HA) and chondroitin sulfate…”
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Apical-to-basolateral transepithelial transport of cow’s milk caseins by intestinal Caco-2 cell monolayers: MS-based quantitation of cellularly degraded α- and β-casein fragments
Published in Journal of biochemistry (Tokyo) (01-08-2018)“…Abstract Casein (CN) is the major milk protein to nourish infants but, in certain population, it causes cow’s milk allergy, indicating the uptake of antigenic…”
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A lactoferrin-receptor, intelectin 1, affects uptake, sub-cellular localization and release of immunochemically detectable lactoferrin by intestinal epithelial Caco-2 cells
Published in Journal of biochemistry (Tokyo) (01-11-2013)“…Intelectin 1 (IntL) is known as a lectin expressed in intestinal epithelia and also as a receptor for an iron-binding protein, lactoferrin (LF). Uptake of LF…”
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FcRY is a key molecule controlling maternal blood IgY transfer to yolks during egg development in avian species
Published in Frontiers in immunology (29-02-2024)“…Maternal immunoglobulin transfer plays a key role in conferring passive immunity to neonates. Maternal blood immunoglobulin Y (IgY) in avian species is…”
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Evaluation of allergenic potential for rice seed protein components utilizing a rice proteome database and an allergen database in combination with IgE-binding of recombinant proteins
Published in Bioscience, biotechnology, and biochemistry (03-03-2016)“…Among 131 rice endosperm proteins previously identified by MS-based proteomics, most of the proteins showed low or almost no sequence similarity to known…”
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Intracellular Retention and Subsequent Release of Bovine Milk Lactoferrin Taken Up by Human Enterocyte-Like Cell Lines, Caco-2, C2BBe1 and HT-29
Published in Bioscience, biotechnology, and biochemistry (2013)“…Lactoferrin (LF) is an iron-binding glycoprotein contained in milk and other exocrine fluids, and is believed to have multiple biological functions. We…”
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Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: Potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis
Published in Gene (25-05-2013)“…Recent studies have revealed heterogeneity in the structure of eukaryotic cytoplasmic ribosomes, including a difference in protein composition. It has been…”
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A protective effect of milk fat globule EGF factor VIII (MFG-E8) on the spontaneous fusion of milk fat globules in breast milk
Published in Journal of biochemistry (Tokyo) (01-07-2015)“…Lipid droplets synthesized in mammary epithelial cells are secreted into breast milk by the budding-off mechanism. The milk lipids, termed mik fat globules…”
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Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components
Published in Development (Cambridge) (15-07-2010)“…Cellular junction formation is an elaborate process that is dependent on the regulated synthesis, assembly and membrane targeting of constituting components…”
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Re-Evaluation of Milk-Fat Globule EGF-Factor VIII (MFG-E8) as an Intrinsic Component of the Mouse Milk-Fat Globule Membrane
Published in Bioscience, biotechnology, and biochemistry (2012)“…In lactating mammary glands, milk fat is secreted as fat globules surrounded by a cell plasma membrane containing characteristic membrane-associated proteins…”
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Dephosphorylation reduces passage of ovalbumin antigen through intestinal epithelial Caco-2 cell monolayers
Published in Journal of biochemistry (Tokyo) (01-04-2013)“…Allergenic potential of food proteins is associated with stability to gastric and pancreatic digestive enzymes. However, much attention has not been focused on…”
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The murine Gcap14 gene encodes a novel microtubule binding and bundling protein
Published in FEBS letters (21-05-2012)“…► Gcap14 is a newly found microtubule-associated protein in mammals. ► Gcap14 is shown to bind to microtubules directly. ► Gcap14 induces bundling of…”
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Post-weaning increases in the milk-fat globule EGF-factor VIII on fat globules in mouse milk and in the uptake of the fat globules by HC11 mammary epithelial cells
Published in Journal of biochemistry (Tokyo) (01-01-2013)“…Milk fat globules (MFGs) secreted by lactating mammary gland are unique lipid surrounded by a phospholipid bi-layer. We report here post-weaning changes in MFG…”
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Allergenic potential of rice-pollen proteins: expression, immuno-cross reactivity and IgE-binding
Published in Journal of biochemistry (Tokyo) (01-08-2013)Get full text
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Analysis of protein dynamics within the septate junction reveals a highly stable core protein complex that does not include the basolateral polarity protein Discs large
Published in Journal of cell science (15-08-2011)“…Barrier junctions prevent pathogen invasion and restrict paracellular leakage across epithelial sheets. To understand how one barrier junction, the septate…”
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Vitamin C deficiency alters the transcriptome of the rat brain in a glucocorticoid-dependent manner, leading to microglial activation and reduced neurogenesis
Published in The Journal of nutritional biochemistry (01-06-2024)“…Vitamin C (VitC) is maintained at high concentrations in the brain and is an essential micronutrient for brain function. VitC deficiency leads to…”
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A pericellular hyaluronan matrix is required for the morphological maturation of cortical neurons
Published in Biochimica et biophysica acta. General subjects (01-10-2020)“…Hyaluronan (HA) is a major component of the extracellular matrix (ECM) and is involved in many cellular functions. In the adult brain, HA forms macromolecular…”
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Extracellular vesicle‐mediated MFG‐E8 localization in the extracellular matrix is required for its integrin‐dependent function in mouse mammary epithelial cells
Published in Genes to cells : devoted to molecular & cellular mechanisms (01-10-2017)“…Milk fat globule‐EGF factor 8 (MFG‐E8) is a divalent‐binding secretory protein possessing an Arg‐Gly‐Asp (RGD) motif and a phosphatidylserine (PS)‐binding…”
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The mRNA‐binding protein Serbp1 as an auxiliary protein associated with mammalian cytoplasmic ribosomes
Published in Cell biochemistry and function (01-08-2018)“…While transcription plays an obviously important role in gene expression, translation has recently been emerged as a key step that defines the composition and…”
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