Search Results - "Oshi, Murtada A"
-
1
Colon-targeted delivery of cyclosporine A using dual-functional Eudragit ® FS30D/PLGA nanoparticles ameliorates murine experimental colitis
Published in International journal of nanomedicine (01-01-2018)“…Colon-targeted oral nanoparticles (NPs) have emerged as an ideal, safe, and effective therapy for ulcerative colitis (UC) owing to their ability to selectively…”
Get full text
Journal Article -
2
Colitis-targeted hybrid nanoparticles-in-microparticles system for the treatment of ulcerative colitis
Published in Acta biomaterialia (15-10-2020)“…Nanoparticle (NP)-based drug delivery systems accumulate in the disrupted epithelium of inflamed colon tissue in ulcerative colitis. However, premature early…”
Get full text
Journal Article -
3
Bacteria-Targeted Clindamycin Loaded Polymeric Nanoparticles: Effect of Surface Charge on Nanoparticle Adhesion to MRSA, Antibacterial Activity, and Wound Healing
Published in Pharmaceutics (15-05-2019)“…Adhesion of nanoparticles (NPs) to the bacterial cell wall by modifying their physicochemical properties can improve the antibacterial activity of antibiotic…”
Get full text
Journal Article -
4
pH-Responsive Alginate-Based Microparticles for Colon-Targeted Delivery of Pure Cyclosporine A Crystals to Treat Ulcerative Colitis
Published in Pharmaceutics (06-09-2021)“…Cyclosporine A (CsA) is a potent immunosuppressant for treating ulcerative colitis (UC). However, owing to severe systemic side effects, CsA application in UC…”
Get full text
Journal Article -
5
Development of PLGA micro- and nanorods with high capacity of surface ligand conjugation for enhanced targeted delivery
Published in Asian journal of pharmceutical sciences (01-01-2019)“…Particle shape has been recognized as one of the key properties of nanoparticles in biomedical applications including targeted drug delivery. Targeting ability…”
Get full text
Journal Article -
6
Curcumin Nanocrystal/pH-Responsive Polyelectrolyte Multilayer Core–Shell Nanoparticles for Inflammation-Targeted Alleviation of Ulcerative Colitis
Published in Biomacromolecules (14-09-2020)“…In this study, we developed oral core–shell nanoparticles composed of curcumin nanocrystals in the core and chitosan/alginate multilayers in the shell for…”
Get full text
Journal Article -
7
Colon-targeted dexamethasone microcrystals with pH-sensitive chitosan/alginate/Eudragit S multilayers for the treatment of inflammatory bowel disease
Published in Carbohydrate polymers (15-10-2018)“…•Dexamethasone microcrystals with colon-targeted chitosan/alginate/Eudragit S multilayers were fabricated.•Unwanted burst release of dexamethasone was…”
Get full text
Journal Article -
8
pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via selective accumulation in inflamed colon regions
Published in Nanomedicine (01-04-2018)“…In this study, we developed pH-triggered surface charge-reversal lipid nanoparticles (LNPs), loaded with budesonide, which could precisely deliver the drug to…”
Get full text
Journal Article -
9
A simple approach to enhance dissolution of commercial paracetamol tablets for fast relief of pain
Published in BrJP (2024)“…BACKGROUND AND OBJECTIVES: Pain is considered a major clinical problem worldwide. Faster pain relief was reportedly achieved using a fast-dissolving…”
Get full text
Journal Article -
10
Bioavailability and Antihyperglycemic Effect of Four Glibenclamide Tablets: A Comparative Study
Published in Borneo Journal of Pharmacy (30-11-2023)“…This study compared the bioavailability and antihyperglycemic effect of 5 mg glibenclamide tablets available in Sudan. Nine healthy subjects were given a 5 mg…”
Get full text
Journal Article -
11
Nanomaterials for chronic inflammatory diseases: the current status and future prospects
Published in Applied nanoscience (01-11-2022)“…Over the past decades, nanomedicine, the medical application of nanotechnology, has been extensively investigated as a promising approach in treating different…”
Get full text
Journal Article -
12
Market Survey and Assessment of the Real Demand of Amoxicillin 500mg Capsules in the Sudanese Pharmaceutical Markets
Published in Life and Science (02-02-2021)“…Objective: To determine the current supply and demand for Amoxicillin 500 mg capsules at the pharmaceutical market level based on readily available and…”
Get full text
Journal Article -
13
Uma abordagem simples para melhorar a dissolução de comprimidos comerciais de paracetamol para alívio rápido da dor
Published in BrJP (2024)Get full text
Journal Article