Search Results - "Osei, Emmanuel Twumasi"

In vitro co-culture studies and the crucial role of fibroblast-immune cell crosstalk in IPF pathogenesis by Thiam, Fama, Phogat, Sakshi, Abokor, Filsan Ahmed, Osei, Emmanuel Twumasi

“…IPF is a fatal lung disease characterized by intensive remodeling of lung tissue leading to respiratory failure. The remodeling in IPF lungs is largely…”
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3D in vitro hydrogel models to study the human lung extracellular matrix and fibroblast function by Phogat, Sakshi, Thiam, Fama, Al Yazeedi, Safiya, Abokor, Filsan Ahmed, Osei, Emmanuel Twumasi

“…The pulmonary extracellular matrix (ECM) is a macromolecular structure that provides mechanical support, stability and elastic recoil for different pulmonary…”
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Modeling Extracellular Matrix-Cell Interactions in Lung Repair and Chronic Disease by Hackett, Tillie Louise, Osei, Emmanuel Twumasi

“…The lung extracellular matrix (ECM) is a complex and dynamic mixture of fibrous proteins (collagen, elastin), glycoproteins (fibronectin, laminin),…”
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What Have In Vitro Co-Culture Models Taught Us about the Contribution of Epithelial-Mesenchymal Interactions to Airway Inflammation and Remodeling in Asthma? by Osei, Emmanuel Twumasi, Booth, Steven, Hackett, Tillie-Louise

“…As the lung develops, epithelial-mesenchymal crosstalk is essential for the developmental processes that drive cell proliferation, differentiation, and…”
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The contribution of reticular basement membrane proteins to basal airway epithelial attachment, spreading and barrier formation: implications for airway remodeling in asthma by Hsieh, Aileen, Yang, Chen Xi, Al-Fouadi, May, Nwozor, Kingsley Okechukwu, Osei, Emmanuel Twumasi, Hackett, Tillie-Louise

“…RationaleIn the healthy lung, the pseudostratified conducting airway epithelium is anchored to the reticular basement membrane (RBM) via hemidesmosome junction…”
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Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma by Tam, Anthony, Osei, Emmanuel Twumasi, Cheung, Chung Y, Hughes, Michael, Yang, Chen X, McNagny, Kelly M, Dorscheid, Delbert R, Singhera, Gurpreet K, Hallstrand, Teal S, Warner, Stephanie, Hogg, James C, Hackett, Tillie L, Lim, Chinten J, Sin, Don D

“…Genome-wide association studies (GWAS) have shown that variants of patched homolog 1 (PTCH1) are associated with lung function abnormalities in the general…”
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Interleukin-1α inhibits transforming growth factor-β1 and β2-induced extracellular matrix production, remodeling and signaling in human lung fibroblasts: Master regulator in lung mucosal repair by Usman, Kauna, Fouadi, May, Nwozor, Kingsley Okechukwu, Aminazadeh, Fatemeh, Nair, Parameswaran, Luo, Honglin, Sin, Don D., Osei, Emmanuel Twumasi, Hackett, Tillie-Louise

“…•Interleukin (IL)−1α suppresses transforming growth factor (TGF)-β1/-β2-induced extracellular matrix production, remodeling and myofibroblast differentiation…”
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