Search Results - "Osborne, M."

A Gaussian process framework for modelling stellar activity signals in radial velocity data by Rajpaul, V., Aigrain, S., Osborne, M. A., Reece, S., Roberts, S.

“…To date, the radial velocity (RV) method has been one of the most productive techniques for detecting and confirming extrasolar planetary candidates…”
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Chaste: an open source C++ library for computational physiology and biology by Mirams, Gary R, Arthurs, Christopher J, Bernabeu, Miguel O, Bordas, Rafel, Cooper, Jonathan, Corrias, Alberto, Davit, Yohan, Dunn, Sara-Jane, Fletcher, Alexander G, Harvey, Daniel G, Marsh, Megan E, Osborne, James M, Pathmanathan, Pras, Pitt-Francis, Joe, Southern, James, Zemzemi, Nejib, Gavaghan, David J

“…Chaste - Cancer, Heart And Soft Tissue Environment - is an open source C++ library for the computational simulation of mathematical models developed for…”
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Gaussian processes for time-series modelling by Roberts, S., Osborne, M., Ebden, M., Reece, S., Gibson, N., Aigrain, S.

“…In this paper, we offer a gentle introduction to Gaussian processes for time-series data analysis. The conceptual framework of Bayesian modelling for…”
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Flare kernels may be smaller than you think: modelling the radiative response of chromospheric plasma adjacent to a solar flare by Osborne, Christopher M J, Fletcher, Lyndsay

“…ABSTRACT Numerical models of solar flares typically focus on the behaviour of directly heated flare models, adopting magnetic-field-aligned, plane-parallel…”
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Multiscale modelling of desquamation in the interfollicular epidermis by Miller, Claire, Crampin, Edmund, Osborne, James M

“…Maintenance of epidermal thickness is critical to the barrier function of the skin. Decreased tissue thickness, specifically in the stratum corneum (the…”
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Machine learning enables completely automatic tuning of a quantum device faster than human experts by Moon, H., Lennon, D. T., Kirkpatrick, J., van Esbroeck, N. M., Camenzind, L. C., Yu, Liuqi, Vigneau, F., Zumbühl, D. M., Briggs, G. A. D., Osborne, M. A., Sejdinovic, D., Laird, E. A., Ares, N.

“…Variability is a problem for the scalability of semiconductor quantum devices. The parameter space is large, and the operating range is small. Our statistical…”
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Comparing individual-based approaches to modelling the self-organization of multicellular tissues by Osborne, James M, Fletcher, Alexander G, Pitt-Francis, Joe M, Maini, Philip K, Gavaghan, David J

“…The coordinated behaviour of populations of cells plays a central role in tissue growth and renewal. Cells react to their microenvironment by modulating…”
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A Gaussian process framework for modelling instrumental systematics: application to transmission spectroscopy by Gibson, N. P., Aigrain, S., Roberts, S., Evans, T. M., Osborne, M., Pont, F.

“…Transmission spectroscopy, which consists of measuring the wavelength-dependent absorption of starlight by a planet's atmosphere during a transit, is a…”
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Spatial information allows inference of the prevalence of direct cell-to-cell viral infection by Williams, Thomas, McCaw, James M, Osborne, James M

“…The role of direct cell-to-cell spread in viral infections-where virions spread between host and susceptible cells without needing to be secreted into the…”
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Cooperation, competition and antibiotic resistance in bacterial colonies by Frost, Isabel, Smith, William P. J., Mitri, Sara, Millan, Alvaro San, Davit, Yohan, Osborne, James M., Pitt-Francis, Joe M., MacLean, R. Craig, Foster, Kevin R.

“…Bacteria commonly live in dense and genetically diverse communities associated with surfaces. In these communities, competition for resources and space is…”
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Maintaining the proliferative cell niche in multicellular models of epithelia by Miller, Claire, Crampin, Edmund, Osborne, James M.

“…•Current in silico multicellular models of the epithelia potentially cause erroneous loss of stem cells from the stem cell niche.•Niche populations can be…”
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The role of Th17 cells in the pathophysiology of pregnancy and perinatal mood and anxiety disorders by Osborne, Lauren M., Brar, Amitoj, Klein, Sabra L.

“…•T-cell dysregulation in pregnancy is related to pregnancy morbidities.•There is evidence of TH17 cell dysregulation in non-pregnant depression & anxiety.•TH17…”
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Paneth Cell-Rich Regions Separated by a Cluster of Lgr5+ Cells Initiate Crypt Fission in the Intestinal Stem Cell Niche by Langlands, Alistair J, Almet, Axel A, Appleton, Paul L, Newton, Ian P, Osborne, James M, Näthke, Inke S

“…The crypts of the intestinal epithelium house the stem cells that ensure the continual renewal of the epithelial cells that line the intestinal tract. Crypt…”
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RADYNVERSION: Learning to Invert a Solar Flare Atmosphere with Invertible Neural Networks by Osborne, Christopher M. J., Armstrong, John A., Fletcher, Lyndsay

“…During a solar flare, it is believed that reconnection takes place in the corona followed by fast energy transport to the chromosphere. The resulting intense…”
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Uncertainty in simulating wheat yields under climate change by Asseng, S, Ewert, F, Rosenzweig, C, Jones, J. W, Hatfield, J. L, Ruane, A. C, Boote, K. J, Thorburn, P. J, Rötter, R. P, Cammarano, D

“…Projections of climate change impacts on crop yields are inherently uncertain1. Uncertainty is often quantified when projecting future greenhouse gas emissions…”
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Sex differences in response to obesity and caloric restriction on cognition and hippocampal measures of autophagic-lysosomal transcripts and signaling pathways by Baer, Sadie B, Dorn, Adrianah D, Osborne, Danielle M

“…Obesity rates in the U.S. continue to increase, with nearly 50% of the population being either obese or morbidly obese. Obesity, along with female sex, are…”
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Microvessel isolation protocol for RNA visualization and profiling by Naranjo, Oandy, Osborne, Olivia M, Torices, Silvia, Schmidlin, Sarah, Tiburcio, Destiny, Park, Minseon, Toborek, Michal

“…Disruptions in pericyte and endothelial cell communication can compromise the integrity of the blood-brain barrier (BBB), leading to neurovascular dysfunction…”
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Increasing influence of heat stress on French maize yields from the 1960s to the 2030s by Hawkins, Ed, Fricker, Thomas E., Challinor, Andrew J., Ferro, Christopher A. T., Ho, Chun Kit, Osborne, Tom M.

“…Improved crop yield forecasts could enable more effective adaptation to climate variability and change. Here, we explore how to combine historical observations…”
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The role of the Hes1 crosstalk hub in Notch-Wnt interactions of the intestinal crypt by Kay, Sophie K, Harrington, Heather A, Shepherd, Sarah, Brennan, Keith, Dale, Trevor, Osborne, James M, Gavaghan, David J, Byrne, Helen M

“…The Notch pathway plays a vital role in determining whether cells in the intestinal epithelium adopt a secretory or an absorptive phenotype. Cell fate…”
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Evidence for a climate signal in trends of global crop yield variability over the past 50 years by Osborne, T M, Wheeler, T R

“…Low variability of crop production from year to year is desirable for many reasons, including reduced income risk and stability of supplies. Therefore, it is…”
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