Search Results - "Osborne, J.W."

The semen microbiome and its relationship with local immunology and viral load in HIV infection by Liu, Cindy M, Osborne, Brendan J W, Hungate, Bruce A, Shahabi, Kamnoosh, Huibner, Sanja, Lester, Richard, Dwan, Michael G, Kovacs, Colin, Contente-Cuomo, Tania L, Benko, Erika, Aziz, Maliha, Price, Lance B, Kaul, Rupert

“…Semen is a major vector for HIV transmission, but the semen HIV RNA viral load (VL) only correlates moderately with the blood VL. Viral shedding can be…”
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Antiretroviral therapy in HIV-infected elite controllers: impact on gut immunology, microbial translocation, and biomarkers of serious non-AIDS conditions by Kim, Connie J, Kovacs, Colin, Chun, Tae-Wook, Kandel, Gabor, Osborne, Brendan J W, Huibner, Sanja, Shahabi, Kamnoosh, Yue, Feng-Yun, Benko, Erika, Ostowski, Mario, Kaul, Rupert

“…Elite controllers (ECs) maintain undetectable HIV viral loads without antiretroviral therapy (ART) but are at increased risk of serious non-AIDS conditions…”
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Impact of Antiretroviral Therapy Duration and Intensification on Isolated Shedding of HIV-1 RNA in Semen by Osborne, Brendan J. W., Sheth, Prameet M., Yi, Tae Joon, Kovacs, Colin, Benko, Erika, la Porte, Charles, Huibner, Sanja, Le, Anh Q., Danroth, Ryan, Baraki, Bemuluyigza, Mazzulli, Tony, Brumme, Zabrina L., Kaul, Rupert

“…Background. Effective antiretroviral therapy (ART) dramatically reduces human immunodeficiency virus (HIV) transmission. However, isolated shedding of HIV type…”
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Schistosoma mansoni: Is acquired immunity induced by highly X-irradiated cercariae dependent on the size of the challenging dose? by Hsu, S.Y.L, Hsu, H.F, Osborne, J.W, Johnson, S.C

“…Schistosoma mansoni, mice immunized with highly X-irradiated cercariae, relationship of acquired immunity to size of challenging dose…”
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Latent TGF-β1 is Compartmentalized Between Blood and Seminal Plasma of HIV-Positive Men and Its Activation in Semen is Negatively Correlated with Viral Load and Immune Activation by Kafka, Jessica K., Osborne, Brendan J.W., Sheth, Prameet M., Nazli, Aisha, Dizzell, Sara, Huibner, Sanja, Kovacs, Colin, Verschoor, Chris P., Bowdish, Dawn M., Kaul, Rupert, Kaushic, Charu

“…Problem Semen is the primary medium for sexual transmission of HIV‐1 and contains high concentrations of TGF‐β1, but its role in regulating HIV‐mediated immune…”
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Clinical and Mucosal Immune Correlates of HIV-1 Semen Levels in Antiretroviral-Naive Men by Osborne, Brendan J W, Marsh, Angie K, Huibner, Sanja, Shahabi, Kamnoosh, Liu, Cindy, Contente, Tania, Nagelkerke, Nico J D, Kovacs, Colin, Benko, Erika, Price, Lance, MacDonald, Kelly S, Kaul, Rupert

“…This study was done to characterize parameters associated with semen human immunodeficiency virus (HIV)-1 ribonucleic acid (RNA) viral load (VL) variability in…”
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Impact of collection method on assessment of semen HIV RNA viral load by Osborne, Brendan J W, Sheth, Prameet M, Kovacs, Colin, Mazzulli, Tony, Kaul, Rupert

“…The blood HIV RNA viral load is the best-defined predictor of HIV transmission, in part due to ease of measurement and the correlation of blood and genital…”
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The performance of bonded vs. pin-retained complex amalgam restorations: a five-year clinical evaluation by Summitt, J B, Burgess, J O, Berry, T G, Robbins, J W, Osborne, J W, Haveman, C W

“…The authors compared the clinical performance of complex amalgam restorations, replacing at least one cusp--retained either mechanically with self-threading…”
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Drug development risk in HIV-1 clinical trials: the effect of drug class by Osborne, Brendan J.W., Kaul, Rupert, Parker, Jayson L.

“…Objectives  This study analysed the risk of clinical trial failure in drug development for Human Immunodeficiency Virus‐1 (HIV) between 1998 and 2008 in order…”
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Drug development risk in HIV-1 clinical trials: the effect of drug class: New drug development for HIV-1 by Osborne, Brendan J.W., Kaul, Rupert, Parker, Jayson L.

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Long-term corrosion of a Ga-containing restorative material by Sarkar, N.K., Moiseyeva, R., Berzins, D.W., Osborne, J.W.

“…Objective: The aim was to simulate and characterize the long-term corrosion of a Ga-containing alloy (Galloy, SDI). Methods: To induce corrosion, cylindrical…”
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Clinical evaluation and microstructural analysis of a direct placement gallium restorative alloy by Neo, J, Chew, C L, Osborne, J W, Mahler, D B

“…The objective of this study was to assess the clinical performance of a direct placement gallium alloy sealed with an established dentine adhesive system. In…”
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The effect of pentoxifylline on early and late radiation injury following fractionated irradiation in C3H mice by Dion, M W, Hussey, D H, Osborne, J W

“…An experiment was performed to test the effectiveness of pentoxifylline in reducing late radiation injury. One hundred and four C3H mice were randomized into…”
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Effects of accelerated fractionation on radiation injury of the small intestine: a new rat model by Hauer-Jensen, M, Poulakos, L, Osborne, J W

“…The present study assessed the influence of shortening the overall treatment time (accelerated fractionation) on radiation injury of the small intestine. A rat…”
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Dental amalgam and mercury vapor release by Osborne, J W

“…Dental diseases are among the most common ailments, and dentists in the United States spend over 50% of their time in dental practice rebuilding carious,…”
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Relationship of restoration width, tooth position, and alloy to fracture at the margins of 13- to 14-year-old amalgams by Osborne, J W, Gale, E N

“…The effect of width of the restoration, tooth position, and amalgam type on the fracture of the margins of 13- to 14-year-old, high-copper, amalgam…”
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Characterization of induced pulpal hypoxia using 3H-misonidazole by Baumgardner, K R, Osborne, J W, Walton, R E, Born, J L

“…Tritiated misonidazole (3H-MISO) is a bioreductively activated marker which preferentially binds to cells with decreased oxygen tension (hypoxia). Detection of…”
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Induced hypoxia in rat pulp and periapex demonstrated by 3H-misonidazole retention by Baumgardner, K R, Walton, R E, Osborne, J W, Born, J L

“…Cellular hypoxia may be a useful indication of tissue distress in the dental pulp that could be used to investigate the early stages of pulpal responses…”
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13-year clinical assessment of 10 amalgam alloys by Osborne, J W, Norman, R D

“…The first commercial high-copper amalgam was developed in the mid-1960's. In 1975, a study to evaluate in vivo/in vitro performance of nine of these new alloys…”
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Crypt fission in the small intestine of the rat by Clair, W.H. St, Osborne, J.W.

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