Search Results - "Osakunor, Derick"

Paediatric schistosomiasis: What we know and what we need to know by Osakunor, Derick N M, Woolhouse, Mark E J, Mutapi, Francisca

“…Schistosomiasis affects over 200 million people worldwide, most of whom are children. Research and control strategies directed at preschool-aged children…”
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Six rounds of annual praziquantel treatment during a national helminth control program significantly reduced schistosome infection and morbidity levels in a cohort of schoolchildren in Zimbabwe by Mduluza, Takafira, Jones, Caitlin, Osakunor, Derick N. M., Lim, Rivka, Kuebel, Julius K., Phiri, Isaac, Manangazira, Portia, Tagwireyi, Paradzayi, Mutapi, Francisca

“…Background The World Health Organization recommends that schistosomiasis be treated through Mass Drug Administration (MDA). In line with this recommendation,…”
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Schistosomiasis Control: Leave No Age Group Behind by Faust, Christina L., Osakunor, Derick N.M., Downs, Jennifer A., Kayuni, Sekeleghe, Stothard, J. Russell, Lamberton, Poppy H.L., Reinhard-Rupp, Jutta, Rollinson, David

“…Despite accelerating progress towards schistosomiasis control in sub-Saharan Africa, several age groups have been eclipsed by current treatment and monitoring…”
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Investigating a strategy for quantifying schistosome infection levels in preschool-aged children using prevalence data from school-aged children by Lim, Rivka M, Woolhouse, Mark E J, Mduluza, Takafira, Chase-Topping, Margo, Osakunor, Derick N M, Chitsulo, Lester, Mutapi, Francisca

“…In 2012, the World Health Organisation (WHO) set out a roadmap for eliminating schistosomiasis as a public health problem by 2025. To achieve this target,…”
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Host tissue proteomics reveal insights into the molecular basis of Schistosoma haematobium-induced bladder pathology by Osakunor, Derick N M, Ishida, Kenji, Lamanna, Olivia K, Rossi, Mario, Dwomoh, Louis, Hsieh, Michael H

“…Urogenital schistosomiasis remains a major public health concern worldwide. In response to egg deposition, the host bladder undergoes gross and molecular…”
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Schistosoma haematobium infection is associated with alterations in energy and purine-related metabolism in preschool-aged children by Osakunor, Derick N M, Mduluza, Takafira, Osei-Hyiaman, Douglas, Burgess, Karl, Woolhouse, Mark E J, Mutapi, Francisca

“…Helminths are parasitic worms that infect over a billion people worldwide. The pathological consequences from infection are due in part, to parasite-induced…”
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Elevation of C-reactive protein, P-selectin and Resistin as potential inflammatory biomarkers of urogenital Schistosomiasis exposure in preschool children by Chimponda, Theresa N, Mushayi, Caroline, Osakunor, Derick N M, Vengesai, Arthur, Enwono, Eyoh, Amanfo, Seth, Murray, Janice, Tshuma, Cremance, Mutapi, Francisca, Mduluza, Takafira

“…Schistosomiasis is known to induce inflammatory immune responses. C-reactive protein (CRP), resistin and P-selectin are serological inflammatory markers that…”
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The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children by Osakunor, Derick N. M., Munk, Patrick, Mduluza, Takafira, Petersen, Thomas N., Brinch, Christian, Ivens, Alasdair, Chimponda, Theresa, Amanfo, Seth A., Murray, Janice, Woolhouse, Mark E. J., Aarestrup, Frank M., Mutapi, Francisca

“…Helminth parasites have been shown to have systemic effects in the host. Using shotgun metagenomic sequencing, we characterise the gut microbiome and resistome…”
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Assessing early child development and its association with stunting and schistosome infections in rural Zimbabwean children using the Griffiths Scales of Child Development by Mutapi, Francisca, Pfavayi, Lorraine, Osakunor, Derick, Lim, Rivka, Kasambala, Maritha, Mutemeri, Arnold, Rusakaniko, Simbarashe, Chibanda, Dixon, Mduluza, Takafira

“…There is a paucity of reference early childhood development (ECD) data at community level in rural Africa. Our objective was to conduct a comprehensive…”
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Serum calcium and magnesium levels in women presenting with pre-eclampsia and pregnancy-induced hypertension: a case-control study in the Cape Coast metropolis, Ghana by Ephraim, Richard Kobina Dadzie, Osakunor, Derick Nii Mensah, Denkyira, Seth Wiredu, Eshun, Henrietta, Amoah, Samuel, Anto, Enoch Odame

“…Hypertensive disorders of pregnancy are important causes of morbidity and mortality. The levels of calcium (Ca2+) and magnesium (Mg2+) in pregnancy may…”
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Laboratory prediction of primary postpartum haemorrhage: a comparative cohort study by Owiredu, William K B A, Osakunor, Derick N M, Turpin, Cornelius A, Owusu-Afriyie, Osei

“…Postpartum haemorrhage (PPH) is the leading cause of maternal deaths, the world over. The aim of this study was to determine laboratory parameters that could…”
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Cytopathology practice in Kumasi: A 2-year retrospective audit by Duduyemi, Babatunde, Owusu-Afriyie, Osei, Danquah, Kwabena, Osakunor, Derick

“…Aim: Surgical pathology service is generally unavailable in most developing countries and comes with challenges. Cytopathology is a reliable, inexpensive…”
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Coinfections and comorbidities in African health systems: At the interface of infectious and noninfectious diseases by Osakunor, Derick Nii Mensah, Sengeh, David Moinina, Mutapi, Francisca

“…There is a disease epidemiological transition occurring in Africa, with increasing incidence of noninfectious diseases, superimposed on a health system…”
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Obesity and Cardio-Metabolic Risk Factors in an Urban and Rural Population in the Ashanti Region-Ghana: A Comparative Cross-Sectional Study by Obirikorang, Christian, Osakunor, Derick Nii Mensah, Anto, Enoch Odame, Amponsah, Samuel Opoku, Adarkwa, Opei Kwafo

“…There is a surge in chronic diseases in the developing world, driven by a high prevalence of cardio-metabolic risk factors. This study described differences in…”
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Hepatic Enzyme Alterations in HIV Patients on Antiretroviral Therapy: A Case-Control Study in a Hospital Setting in Ghana by Osakunor, Derick Nii Mensah, Obirikorang, Christian, Fianu, Vincent, Asare, Isaac, Dakorah, Mavis

“…Diagnosing hepatic injury in HIV infection can be a herculean task for clinicians as several factors may be involved. In this study, we sought to determine the…”
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Determinants of crystalluria among type 2 diabetes patients; A case-control study of the Agona West Municipality, Ghana by Ephraim, Richard, Anoff, Kwaku, Brenyah, Ruth, Osakunor, Derick, Sakyi, Samuel, Osei-Yeboah, James, Anto, Enoch

“…Background/Aim: Type 2 diabetes mellitus (T2DM) has been implicated as a risk factor for nephrolithiasis. The aim of this study was to determine the prevalence…”
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Renal function in Ghanaian HIV-infected patients on highly active antiretroviral therapy: a case-control study by Obirikorang, Christian, Osakunor, Derick Nii Mensah, Ntaadu, Benedict, Adarkwa, Opei Kwafo

“…HAART is anticipated to result in an increase in long-term survival, but may present with the development of associated complications. The aim of this study…”
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Crystalluria in HIV/AIDS patients on highly active anti-retroviral therapy in the Kumasi metropolis; a cross sectional study by Ephraim, Richard K D, Brenyah, Ruth C, Osei, Richmond, Bossipe, Bright D, Adoba, Prince, Osakunor, Derick N M, Agbodzakey, Hope

“…Crystalluria is associated with some highly active anti-retroviral therapies (HAART's) used in the management of HIV/AIDS. This study used light microscopy to…”
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Anaemia and Iron Homeostasis in a Cohort of HIV-Infected Patients: A Cross-Sectional Study in Ghana by Obirikorang, Christian, Issahaku, Razak Gyesi, Osakunor, Derick Nii Mensah, Osei-Yeboah, James

“…Aim. We determined the prevalence of anaemia and evaluated markers of iron homeostasis in a cohort of HIV patients. Methods. A comparative cross-sectional…”
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Dynamics of paediatric urogenital schistosome infection, morbidity and treatment: a longitudinal study among preschool children in Zimbabwe by Osakunor, Derick Nii Mensah, Mduluza, Takafira, Midzi, Nicholas, Chase-Topping, Margo, Mutsaka-Makuvaza, Masceline Jenipher, Chimponda, Theresa, Eyoh, Enwono, Mduluza, Tariro, Pfavayi, Lorraine Tsitsi, Wami, Welcome Mkululi, Amanfo, Seth Appiah, Murray, Janice, Tshuma, Clement, Woolhouse, Mark Edward John, Mutapi, Francisca

“…BackgroundRecent research has shown that in schistosome-endemic areas preschool-aged children (PSAC), that is, ≤5 years, are at risk of infection. However,…”
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