Search Results - "Osaki, Ayumu"

Artificially Created Reentry Circuit by Laser Irradiation Causes Atrial Tachycardia to Persist in Murine Atria by Horii, Shunpei, Yada, Hirotaka, Ito, Kei, Tsujita, Kazuhiro, Osaki, Ayumu, Kagami, Kazuki, Sato, Atsushi, Kimura, Toyokazu, Yasuda, Risako, Toya, Takumi, Namba, Takayuki, Nagatomo, Yuji, Ido, Yasuo, Miyazaki, Koji, Masaki, Nobuyuki, Ishihara, Miya, Takase, Bonpei, Adachi, Takeshi

“…Background:There is a gradual progression from paroxysmal to persistent atrial fibrillation (AF) in humans. To elucidate the mechanism involved, the creation…”
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Reactive Oxygen Species in the Aorta and Perivascular Adipose Tissue Precedes Endothelial Dysfunction in the Aorta of Mice with a High-Fat High-Sucrose Diet and Additional Factors by Osaki, Ayumu, Kagami, Kazuki, Ishinoda, Yuki, Sato, Atsushi, Kimura, Toyokazu, Horii, Shunpei, Ito, Kei, Toya, Takumi, Ido, Yasuo, Namba, Takayuki, Masaki, Nobuyuki, Nagatomo, Yuji, Adachi, Takeshi

“…Metabolic syndrome (Mets) is the major contributor to the onset of metabolic complications, such as hypertension, type 2 diabetes mellitus (DM), dyslipidemia,…”
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Endothelial Extracellular Signal-Regulated Kinase/Thromboxane A2/Prostanoid Receptor Pathway Aggravates Endothelial Dysfunction and Insulin Resistance in a Mouse Model of Metabolic Syndrome by Sato, Atsushi, Yumita, Yusuke, Kagami, Kazuki, Ishinoda, Yuki, Kimura, Toyokazu, Osaki, Ayumu, Toya, Takumi, Namba, Takayuki, Endo, Shogo, Ido, Yasuo, Nagatomo, Yuji, Satoh, Yasushi, Adachi, Takeshi

“…Background Metabolic syndrome is characterized by insulin resistance, which impairs intracellular signaling pathways and endothelial NO bioactivity, leading to…”
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Resistance to Obesity in SOD1 Deficient Mice with a High-Fat/High-Sucrose Diet by Sato, Atsushi, Shiraishi, Yasunaga, Kimura, Toyokazu, Osaki, Ayumu, Kagami, Kazuki, Ido, Yasuo, Adachi, Takeshi

“…Metabolic syndrome (Mets) is an important condition because it may cause stroke and heart disease in the future. Reactive oxygen species (ROSs) influence the…”
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A Rare Case of Rush Progression of Purulent Pericarditis by Escherichia coli in a Patient with Malignant Lymphoma by Horii, Shunpei, Yada, Hirotaka, Ito, Kei, Osaki, Ayumu, Sato, Atsushi, Kimura, Toyokazu, Yasuda, Risako, Toya, Takumi, Namba, Takayuki, Masaki, Nobuyuki, Adachi, Takeshi

“…Purulent pericarditis is a rare disease in the antibiotic era. The common pathogens of purulent pericarditis are gram-positive species such as Staphylococcus…”
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Sarco/Endoplasmic Reticulum Ca2+ ATPase 2 Activator Ameliorates Endothelial Dysfunction; Insulin Resistance in Diabetic Mice by Kimura, Toyokazu, Kagami, Kazuki, Sato, Atsushi, Osaki, Ayumu, Ito, Kei, Horii, Shunpei, Toya, Takumi, Masaki, Nobuyuki, Yasuda, Risako, Nagatomo, Yuji, Adachi, Takeshi

“…Background: Sarco/endoplasmic reticulum Ca2+-ATPase2 (SERCA2) is impaired in various organs in animal models of diabetes. The purpose of this study was to test…”
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Impact of oxidative posttranslational modifications of SERCA2 on heart failure exacerbation in young patients with non-ischemic cardiomyopathy: A pilot study by Toya, Takumi, Ito, Kei, Kagami, Kazuki, Osaki, Ayumu, Sato, Atsushi, Kimura, Toyokazu, Horii, Shunpei, Yasuda, Risako, Namba, Takayuki, Ido, Yasuo, Nagatomo, Yuji, Hayashi, Katsumi, Masaki, Nobuyuki, Yada, Hirotaka, Adachi, Takeshi

“…Oxidative posttranslational modifications (OPTM) impair the function of Sarcoplasmic/endoplasmic reticulum (SR) calcium (Ca2+) ATPase (SERCA) 2 and trigger…”
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1210-P: Subcutaneous-Depot Specific Adiposity Change Is Associated with the Ectopic Fat Depot and Tissue Damage in High-Fat High-Sucrose (HFHS) Fed Fabp4 Cre-ERK2 Knockout Mice by ISHINODA, YUKI, IDO, YASUO, NOGUCHI, MIDORI, YUMITA, YUSUKE, KAGAMI, KAZUKI, OSAKI, AYUMU, SATOH, YASUSHI, ENDO, SHOGO, KASUGA, AKIRA, ADACHI, TAKESHI, KUMAGAI, HIROO

“…Previous reports suggested that low subcutaneous adiposity increases the risk of cardiovascular events and diabetes. Mechanisms of depot-specific differences…”
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Abstract 11833: Prognostic Value of Diffusion-Weighted Cardiac Magnetic Resonance Imaging in Hospitalized Heart Failure Patients by Kagami, Kazuki, Toya, Takumi, Kuwaki, Shunpei, Sato, Atsushi, Yumita, Yusuke, Osaki, Ayumu, Iwashita, Midori, Yasuda, Risako, Ikegami, Yukinori, Namba, Takayuki, Masaki, Nobuyuki, Nagatomo, Yuji, Steiner, John, Adachi, Takeshi K

“…IntroductionDiffusion-weighted imaging (DWI) has been recognized as the golden standard to detect acute phase cerebral infarction; however, there is a paucity…”
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Artificially Created Reentry Circuit by Laser Irradiation Causes Atrial Tachycardia to Persist in Murine Atria by Horii, Shunpei, Yada, Hirotaka, Ito, Kei, Tsujita, Kazuhiro, Osaki, Ayumu, Kagami, Kazuki, Sato, Atsushi, Kimura, Toyokazu, Yasuda, Risako, Toya, Takumi, Namba, Takayuki, Nagatomo, Yuji, Ido, Yasuo, Miyazaki, Koji, Masaki, Nobuyuki, Ishihara, Miya, Takase, Bonpei, Adachi, Takeshi

“…Background:There is a gradual progression from paroxysmal to persistent atrial fibrillation (AF) in humans. To elucidate the mechanism involved, the creation…”
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Sarco/Endoplasmic Reticulum Ca 2+ ATPase 2 Activator Ameliorates Endothelial Dysfunction; Insulin Resistance in Diabetic Mice by Kimura, Toyokazu, Kagami, Kazuki, Sato, Atsushi, Osaki, Ayumu, Ito, Kei, Horii, Shunpei, Toya, Takumi, Masaki, Nobuyuki, Yasuda, Risako, Nagatomo, Yuji, Adachi, Takeshi

“…Sarco/endoplasmic reticulum Ca -ATPase2 (SERCA2) is impaired in various organs in animal models of diabetes. The purpose of this study was to test the effects…”
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Abstract 12235: Additional Factor With High Fat and High Sucrose Diet is Required for Endothelial Dysfunction in Aorta From Obese Mice by Osaki, Ayumu, Sato, Atsushi, Kimura, Toyokazu, Horii, Shunpei, Ito, Kei, Toya, Takumi, Ido, Yasuo, Namba, Takayuki, Masaki, Nobuyuki, Adachi, Takeshi

“…IntroductionHigh fat and high sucrose diet (HFHSD) induces obesity and insulin resistance. Thus mice with HFHSD is widely used as the model of metabolic…”
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Abstract 12229: Adipose Extracellular Signal-Regulated Kinase 2 Protect From Ectopic Fat Depositions and Endothelial Dysfunction in Obesity by Osaki, Ayumu, Satoh, Yasushi, Endo, Shogo, Sato, Atsushi, Kimura, Toyokazu, Ito, Kei, Toya, Takumi, Ido, Yasuo, Namba, Takayuki, Adachi, Takeshi

“…IntroductionExtracellular signal-regulated kinase (ERK) modulates differentiation and maturation of adipocyte. Adipose tissue plays a critical role in the…”
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Abstract 12233: Extracellular Signal-Regulated Kinase 2 in Perivascular Adipose Tissue Modulates Vascular Tone in Mice by Osaki, Ayumu, Satoh, Yasushi, Endo, Shogo, Sato, Atsushi, Kimura, Toyokazu, Ito, Kei, Toya, Takumi, Ido, Yasuo, Namba, Takayuki, Adachi, Takeshi

“…IntroductionPerivascular adipose tissue (PVAT) was known to modulate vascular tone, however, the mechanism has not been completely clarified yet. The function…”
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Abstract 12458: SERCA2 C674S Heterozygote Knock-In Mice Leads to QT Prolongation and Lethal Ventricular Arrhythmia by Catecholamine Injection and Hypertrophy With AngiotensinII by Ito, Kei, Yada, Hirotaka, Horii, Shunpei, Toya, Takumi, Shiraishi, Yasunaga, Kimura, Toyokazu, Osaki, Ayumu, Sato, Atsushi, Yasuda, Risako, Namba, Takayuki, Nagatomo, Yuji, Masaki, Nobuyuki, Ido, Yasuo, Takase, Bonpei, Adachi, Takeshi

“…IntroductionWe have found that Cys674 on sarcoplasmic reticulum Ca2+-ATPase2 (SERCA2) was oxidized in the heart from patients with cardiomyopathy. However, it…”
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