Search Results - "Ortmann, Olaf"

Endocrine Risk Factors of Endometrial Cancer: Polycystic Ovary Syndrome, Oral Contraceptives, Infertility, Tamoxifen by Ignatov, Atanas, Ortmann, Olaf

“…Endometrial cancer is the most common gynecologic cancer and is predominantly endocrine-related. The role of unopposed estrogen in the development of…”
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Chemerin and Cancer by Treeck, Oliver, Buechler, Christa, Ortmann, Olaf

“…Chemerin is a multifunctional adipokine with established roles in inflammation, adipogenesis and glucose homeostasis. Increasing evidence suggest an important…”
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Expression of estrogen-related receptors in ovarian cancer and impact on survival by Schüler-Toprak, Susanne, Weber, Florian, Skrzypczak, Maciej, Ortmann, Olaf, Treeck, Oliver

“…Purpose This study further approaches the role of estrogen-related receptors (ERRs) in ovarian cancer. Protein expression of ERRα, ERRβ and ERRγ in ovarian…”
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Sedentary behaviour in relation to ovarian cancer risk: a systematic review and meta-analysis by Biller, Veronika S., Leitzmann, Michael F., Sedlmeier, Anja M., Berger, Felix F., Ortmann, Olaf, Jochem, Carmen

“…Sedentary behaviour is an emerging risk factor for several site-specific cancers. Ovarian cancers are often detected at late disease stages and the role of…”
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Effects of Endocrine Interventions Targeting ERα or PR on Breast Cancer Risk in the General Population and Carriers of BRCA1/2 Pathogenic Variants by Huber, Deborah, Hatzipanagiotou, Maria, Schüler-Toprak, Susanne, Ortmann, Olaf, Treeck, Oliver

“…There is evidence suggesting that endocrine interventions such as hormone replacement therapy and hormonal contraception can increase breast cancer (BC) risk…”
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The 3D in vivo chorioallantoic membrane model and its role in breast cancer research by Kohl, Cynthia, Aung, Thiha, Haerteis, Silke, Ignatov, Atanas, Ortmann, Olaf, Papathemelis, Thomas

“…Purpose We aimed to evaluate the role of the chorioallantoic membrane model (CAM) in breast cancer research. Methods The following is an overview of the use of…”
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Effect of Luteinizing Hormone–Releasing Hormone Agonist on Ovarian Function After Modern Adjuvant Breast Cancer Chemotherapy: The GBG 37 ZORO Study by GERBER, Bernd, VON MINCKWITZ, Gunter, FEHM, Tanja, REZAI, Mahdi, MEHTA, Keyur, LOIBL, Sibylle, STEHLE, Heinrich, REIMER, Toralf, FELBERBAUM, Ricardo, MAASS, Nikolai, FISCHER, Dorothea, SOMMER, Harald L, CONRAD, Bettina, ORTMANN, Olaf

“…Observational studies suggested that luteinizing hormone-releasing hormone agonists (LHRHa) might prevent premature ovarian failure resulting from adjuvant…”
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Estrogen Actions in Triple-Negative Breast Cancer by Treeck, Oliver, Schüler-Toprak, Susanne, Ortmann, Olaf

“…Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of estrogen receptors ERβ and G protein-coupled estrogen receptor 1…”
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Compared DNA and RNA quality of breast cancer biobanking samples after long-term storage protocols in − 80 °C and liquid nitrogen by Babel, Maximilian, Mamilos, Andreas, Seitz, Stephan, Niedermair, Tanja, Weber, Florian, Anzeneder, Tobias, Ortmann, Olaf, Dietmaier, Wolfgang, Brochhausen, Christoph

“…Molecular investigations are crucial for further developments in precision medicine. RNA sequencing, alone or in combination with further omic-analyses,…”
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Human Chorionic Gonadotropin and Breast Cancer by Schüler-Toprak, Susanne, Treeck, Oliver, Ortmann, Olaf

“…Breast cancer is well known as a malignancy being strongly influenced by female steroids. Pregnancy is a protective factor against breast cancer. Human…”
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Estrogen receptor beta exerts growth-inhibitory effects on human mammary epithelial cells by Treeck, Oliver, Lattrich, Claus, Springwald, Anette, Ortmann, Olaf

“…Estrogen receptor β (ERβ) is widely expressed in mammary epithelium. ERβ expression is reported to decline during carcinogenesis of the breast and other…”
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Regulation of Programmed Death Ligand 1 (PD-L1) Expression in Breast Cancer Cell Lines In Vitro and in Immunodeficient and Humanized Tumor Mice by Rom-Jurek, Eva-Maria, Kirchhammer, Nicole, Ugocsai, Peter, Ortmann, Olaf, Wege, Anja K, Brockhoff, Gero

“…Programmed death ligand 1 (PD-L1) expression is an efficient strategy of tumor cells to escape immunological eradiation. However, only little is known about…”
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Effect of estrogen receptor β agonists on proliferation and gene expression of ovarian cancer cells by Schüler-Toprak, Susanne, Moehle, Christoph, Skrzypczak, Maciej, Ortmann, Olaf, Treeck, Oliver

“…Estrogen receptor (ER) β has been suggested to affect ovarian carcinogenesis. We examined the effects of four ERβ agonists on proliferation and gene expression…”
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GPER-1 expression is associated with a decreased response rate to primary tamoxifen therapy of breast cancer patients by Ignatov, Tanja, Treeck, Oliver, Kalinski, Thomas, Ortmann, Olaf, Ignatov, Atanas

“…Purpose Endocrine therapies using tamoxifen and/or aromatase inhibitors are important therapeutic options for the targeted treatment of hormone-responsive…”
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Estrogen receptor β is associated with expression of cancer associated genes and survival in ovarian cancer by Schüler-Toprak, Susanne, Weber, Florian, Skrzypczak, Maciej, Ortmann, Olaf, Treeck, Oliver

“…In ovarian cancer, the role of estrogen receptors (ERs), particularly of ERβ, being suggested as tumor suppressor in breast and prostate cancer, remains…”
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Knockdown of estrogen receptor β increases proliferation and affects the transcriptome of endometrial adenocarcinoma cells by Treeck, Oliver, Diepolder, Elisabeth, Skrzypczak, Maciej, Schüler-Toprak, Susanne, Ortmann, Olaf

“…Estrogen receptor β (ERβ) has been repeatedly suggested to play important roles in hormone-dependent cancer like in tumors of the breast, ovary or prostate. In…”
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G protein-coupled estrogen receptor 1 (GPER-1) and agonist G-1 inhibit growth of ovarian cancer cells by activation of anti-tumoral transcriptome responses: impact of GPER-1 mRNA on survival by Schüler-Toprak, Susanne, Skrzypczak, Maciej, Ignatov, Tanja, Ignatov, Atanas, Ortmann, Olaf, Treeck, Oliver

“…Purpose The present study intended to further elucidate the role of G protein-coupled estrogen receptor 1 (GPER-1) in ovarian cancer by comparing the effects…”
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Ovarian epithelial tumors and reproductive factors: a systematic review by Schüler, Susanne, Ponnath, Marvin, Engel, Jörg, Ortmann, Olaf

“…Purpose The aim of this systematic review is to summarize the current knowledge about the etiology and pathogenesis of borderline tumors ovarian cancer with…”
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Peri- and postmenopause—diagnosis and interventions interdisciplinary S3 guideline of the association of the scientific medical societies in Germany (AWMF 015/062): short version by Ortmann, Olaf, Beckermann, Maria J., Inwald, Elisabeth C., Strowitzki, Thomas, Windler, Eberhard, Tempfer, Clemens

“…This short version of the interdisciplinary S3 guideline “Peri- and Postmenopause—Diagnosis and Interventions” is intended as a decision-making instrument for…”
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Minimal-invasive or open approach for surgery of early cervical cancer: the treatment center matters by Gennari, Paolo, Gerken, Michael, Mészáros, József, Klinkhammer-Schalke, Monika, Ortmann, Olaf, Eggemann, Holm, Ignatov, Atanas

“…Purpose The aim of the study was to compare recurrence-free survival (RFS) and overall survival (OS) of patients with early stage cervical cancer in dependence…”
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