Search Results - "Ortiz de Solorzano, Carlos"

Phenotypic and metabolic features of mouse diaphragm and gastrocnemius muscles in chronic lung carcinogenesis: influence of underlying emphysema by Salazar-Degracia, Anna, Blanco, David, Vilà-Ubach, Mònica, de Biurrun, Gabriel, de Solórzano, Carlos Ortiz, Montuenga, Luis M, Barreiro, Esther

“…Muscle wasting negatively impacts the progress of chronic diseases such as lung cancer (LC) and emphysema, which are in turn interrelated. We hypothesized that…”
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Modulation of Haemophilus influenzae interaction with hydrophobic molecules by the VacJ/MlaA lipoprotein impacts strongly on its interplay with the airways by Fernández-Calvet, Ariadna, Rodríguez-Arce, Irene, Almagro, Goizeder, Moleres, Javier, Euba, Begoña, Caballero, Lucía, Martí, Sara, Ramos-Vivas, José, Bartholomew, Toby Leigh, Morales, Xabier, Ortíz-de-Solórzano, Carlos, Yuste, José Enrique, Bengoechea, José Antonio, Conde-Álvarez, Raquel, Garmendia, Junkal

“…Airway infection by nontypeable Haemophilus influenzae (NTHi) associates to chronic obstructive pulmonary disease (COPD) exacerbation and asthma neutrophilic…”
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Adiposoft: automated software for the analysis of white adipose tissue cellularity in histological sections by Galarraga, Miguel, Campión, Javier, Muñoz-Barrutia, Arrate, Boqué, Noemí, Moreno, Haritz, Martínez, José Alfredo, Milagro, Fermín, Ortiz-de-Solórzano, Carlos

“…The accurate estimation of the number and size of cells provides relevant information on the kinetics of growth and the physiological status of a given tissue…”
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3D reconstruction of histological sections: Application to mammary gland tissue by Arganda-Carreras, Ignacio, Fernández-González, Rodrigo, Muñoz-Barrutia, Arrate, Ortiz-De-Solorzano, Carlos

“…In this article, we present a novel method for the automatic 3D reconstruction of thick tissue blocks from 2D histological sections. The algorithm completes a…”
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Heterogenous presence of neutrophil extracellular traps in human solid tumours is partially dependent on IL‐8 by de Andrea, Carlos E, Ochoa, María Carmen, Villalba‐Esparza, María, Teijeira, Álvaro, Schalper, Kurt A, Abengozar‐Muela, Marta, Eguren‐Santamaría, Iñaki, Sainz, Cristina, Sánchez‐Gregorio, Sandra, Garasa, Saray, Ariz, Mikel, Ortiz‐de‐Solorzano, Carlos, Rodriguez‐Ruiz, María E, Perez‐Gracia, Jose L, Lozano, María D, Echeveste, José I, Sanmamed, Miguel F, Melero, Ignacio

“…Neutrophil extracellular traps (NETs) are webs of extracellular nuclear DNA extruded by dying neutrophils infiltrating tissue. NETs constitute a defence…”
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Automated Neuromelanin Imaging as a Diagnostic Biomarker for Parkinson's Disease by Castellanos, Gabriel, Fernández-Seara, María A., Lorenzo-Betancor, Oswaldo, Ortega-Cubero, Sara, Puigvert, Marc, Uranga, Javier, Vidorreta, Marta, Irigoyen, Jaione, Lorenzo, Elena, Muñoz-Barrutia, Arrate, Ortiz-de-Solorzano, Carlos, Pastor, Pau, Pastor, María A.

“…ABSTRACT Background We aimed to analyze the diagnostic accuracy of an automated segmentation and quantification method of the SNc and locus coeruleus (LC)…”
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Development and multimodal characterization of an elastase-induced emphysema mouse disease model for the COPD frequent bacterial exacerbator phenotype by Rodríguez-Arce, Irene, Morales, Xabier, Ariz, Mikel, Euba, Begoña, López-López, Nahikari, Esparza, Maider, Hood, Derek W., Leiva, José, Ortíz-de-Solórzano, Carlos, Garmendia, Junkal

“…Chronic obstructive pulmonary disease (COPD) patients undergo infectious exacerbations whose frequency identifies a clinically meaningful phenotype. Mouse…”
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Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities by Lopez Janeiro, Alvaro, Miraval Wong, Eduardo, Jiménez-Sánchez, Daniel, Ortiz de Solorzano, Carlos, Lozano, Maria D, Teijeira, Alvaro, Schalper, Kurt A, Melero, Ignacio, De Andrea, Carlos E

“…IntroductionThe tissue immune microenvironment is associated with key aspects of tumor biology. The interaction between the immune system and cancer cells has…”
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Weakly supervised deep learning to predict recurrence in low-grade endometrial cancer from multiplexed immunofluorescence images by Jiménez-Sánchez, Daniel, López-Janeiro, Álvaro, Villalba-Esparza, María, Ariz, Mikel, Kadioglu, Ece, Masetto, Ivan, Goubert, Virginie, Lozano, Maria D., Melero, Ignacio, Hardisson, David, Ortiz-de-Solórzano, Carlos, de Andrea, Carlos E.

“…Predicting recurrence in low-grade, early-stage endometrial cancer (EC) is both challenging and clinically relevant. We present a weakly-supervised deep…”
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Muscular and Tendon Degeneration after Achilles Rupture: New Insights into Future Repair Strategies by Gil-Melgosa, Lara, Grasa, Jorge, Urbiola, Ainhoa, Llombart, Rafael, Susaeta Ruiz, Miguel, Montiel, Verónica, Ederra, Cristina, Calvo, Begoña, Ariz, Mikel, Ripalda-Cemborain, Purificación, Prosper, Felipe, Ortiz-de-Solórzano, Carlos, Pons-Villanueva, Juan, Pérez Ruiz, Ana

“…Achilles tendon rupture is a frequent injury with an increasing incidence. After clinical surgical repair, aimed at suturing the tendon stumps back into their…”
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An Image-Based Framework for the Analysis of the Murine Microvasculature: From Tissue Clarification to Computational Hemodynamics by Mañosas, Santiago, Sanz, Aritz, Ederra, Cristina, Urbiola, Ainhoa, Rojas-de-Miguel, Elvira, Ostiz, Ainhoa, Cortés-Domínguez, Iván, Ramírez, Natalia, Ortíz-de-Solórzano, Carlos, Villanueva, Arantxa, Malvè, Mauro

“…The blood–brain barrier is a unique physiological structure acting as a filter for every molecule reaching the brain through the blood. For this reason, an…”
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CRMP2 as a Candidate Target to Interfere with Lung Cancer Cell Migration by Morales, Xabier, Peláez, Rafael, Garasa, Saray, Ortiz de Solórzano, Carlos, Rouzaut, Ana

“…Collapsin response mediator protein 2 (CRMP2) is an adaptor protein that adds tubulin dimers to the growing tip of a microtubule. First described in neurons,…”
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Evaluation of bioluminescent imaging for noninvasive monitoring of colorectal cancer progression in the liver and its response to immunogene therapy by Zabala, Maider, Alzuguren, Pilar, Benavides, Carolina, Crettaz, Julien, Gonzalez-Aseguinolaza, Gloria, Ortiz de Solorzano, Carlos, Gonzalez-Aparicio, Manuela, Kramer, Maria Gabriela, Prieto, Jesus, Hernandez-Alcoceba, Ruben

“…Bioluminescent imaging (BLI) is based on the detection of light emitted by living cells expressing a luciferase gene. Stable transfection of luciferase in…”
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Objective comparison of particle tracking methods by Chenouard, Nicolas, Smal, Ihor, de Chaumont, Fabrice, Maška, Martin, Sbalzarini, Ivo F, Gong, Yuanhao, Cardinale, Janick, Carthel, Craig, Coraluppi, Stefano, Winter, Mark, Cohen, Andrew R, Godinez, William J, Rohr, Karl, Kalaidzidis, Yannis, Liang, Liang, Duncan, James, Shen, Hongying, Xu, Yingke, Magnusson, Klas E G, Jaldén, Joakim, Blau, Helen M, Paul-Gilloteaux, Perrine, Roudot, Philippe, Kervrann, Charles, Waharte, François, Tinevez, Jean-Yves, Shorte, Spencer L, Willemse, Joost, Celler, Katherine, van Wezel, Gilles P, Dan, Han-Wei, Tsai, Yuh-Show, de Solórzano, Carlos Ortiz, Olivo-Marin, Jean-Christophe, Meijering, Erik

“…The first community competition designed to objectively compare the performance of particle tracking algorithms provides valuable practical information for…”
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Combination Strategies in Multi-Atlas Image Segmentation: Application to Brain MR Data by Artaechevarria, X., Munoz-Barrutia, A., Ortiz-de-Solorzano, C.

“…It has been shown that employing multiple atlas images improves segmentation accuracy in atlas-based medical image segmentation. Each atlas image is registered…”
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Characterization of three-dimensional cancer cell migration in mixed collagen-Matrigel scaffolds using microfluidics and image analysis by Anguiano, María, Castilla, Carlos, Maška, Martin, Ederra, Cristina, Peláez, Rafael, Morales, Xabier, Muñoz-Arrieta, Gorka, Mujika, Maite, Kozubek, Michal, Muñoz-Barrutia, Arrate, Rouzaut, Ana, Arana, Sergio, Garcia-Aznar, José Manuel, Ortiz-de-Solorzano, Carlos

“…Microfluidic devices are becoming mainstream tools to recapitulate in vitro the behavior of cells and tissues. In this study, we use microfluidic devices…”
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The use of mixed collagen-Matrigel matrices of increasing complexity recapitulates the biphasic role of cell adhesion in cancer cell migration: ECM sensing, remodeling and forces at the leading edge of cancer invasion by Anguiano, María, Morales, Xabier, Castilla, Carlos, Pena, Alejandro Rodríguez, Ederra, Cristina, Martínez, Martín, Ariz, Mikel, Esparza, Maider, Amaveda, Hippolyte, Mora, Mario, Movilla, Nieves, Aznar, José Manuel García, Cortés-Domínguez, Iván, Ortiz-de-Solorzano, Carlos

“…The migration of cancer cells is highly regulated by the biomechanical properties of their local microenvironment. Using 3D scaffolds of simple composition,…”
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Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood by Rodríguez‐Pena, Alejandro, Armendariz, Estibaliz, Oyarbide, Alvaro, Morales, Xabier, Ortiz‐Espinosa, Sergio, Ruiz‐Fernández de Córdoba, Borja, Cochonneau, Denis, Cornago, Iñaki, Heymann, Dominique, Argemi, Josepmaría, D'Avola, Delia, Sangro, Bruno, Lecanda, Fernando, Pio, Ruben, Cortés‐Domínguez, Iván, Ortiz‐de‐Solórzano, Carlos

“…The analysis of circulating tumor cells (CTCs) in blood is a powerful noninvasive alternative to conventional tumor biopsy. Inertial‐based separation is a…”
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Automatic Segmentation and Quantification of Nigrosome‐1 Neuromelanin and Iron in MRI: A Candidate Biomarker for Parkinson's Disease by Ariz, Mikel, Martínez, Martín, Alvarez, Ignacio, Fernández‐Seara, Maria A., Castellanos, Gabriel, Pastor, Pau, Pastor, Maria A., Ortiz de Solórzano, Carlos

“…Background There is a lack of automated tools for the segmentation and quantification of neuromelanin (NM) and iron in the nigrosome‐1 (N1). Existing tools…”
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Robust, Standardized Quantification of Pulmonary Emphysema in Low Dose CT Exams by Ceresa, Mario, MSc, Bastarrika, Gorka, MD, PhD, de Torres, Juan P., MD, PhD, Montuenga, Luis M., PhD, Zulueta, Javier J., MD, Ortiz-de-Solorzano, Carlos, PhD, Muñoz-Barrutia, Arrate, PhD

“…Rationale and Objectives The aim of this study was to present and evaluate a fully automated system for emphysema quantification on low-dose computed…”
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